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UGID:232497     UniGene Hs.437460     Homo sapiens (human)   TP53
Tumor protein p53 (TP53)

Human protein-coding gene TP53. Represented by 569 ESTs from 247 cDNA libraries. Corresponds to 15 reference sequences (different isoforms). [UniGene 232497 - Hs.437460]

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mammary gland; mouth; uncharacterized tissue; prostate; spleen; intestine; uterus; stomach; testis; eye; lung; amniotic fluid; connective tissue; vascular; ovary; embryonic tissue; thymus; blood; skin; pharynx; liver; pancreas; placenta; lymph node; mixed; heart; kidney; bladder; thyroid; muscle; adrenal gland; lymph; trachea; bone; epididymis; ascites; cervix; esophagus; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13.1
UniSTS entry: Chr 17 GDB:177814
UniSTS entry: Chr 17 GDB:177797
UniSTS entry: Chr 17 PMC310707P2
UniSTS entry: Chr 17 D17S1678 [Map Viewer]
UniSTS entry: Chr 17 D17S1506E
UniSTS entry: Chr 17 GDB:177724
UniSTS entry: Chr 17 GDB:178567
UniSTS entry: Chr 17 GDB:363689
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (64)

AF052180.1 Homo sapiens clone 24564 mRNA sequence A
NM_000546.5 Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA PA
AY429684.1 Homo sapiens tumor suppressor p53 (TP53) mRNA, partial cds P
BT019622.1 Homo sapiens tumor protein p53 (Li-Fraumeni syndrome) mRNA, complete cds P
AK223026.1 Homo sapiens mRNA for tumor protein p53 variant, clone: JTH07296 PA
DQ186652.1 Homo sapiens del133 p53 gamma isoform (TP53) mRNA, complete cds P
DQ186651.1 Homo sapiens del133 p53 beta isoform (TP53) mRNA, complete cds P
DQ186650.1 Homo sapiens del133 p53 isoform (TP53) mRNA, complete cds P
DQ186649.1 Homo sapiens p53 gamma isoform (TP53) mRNA, complete cds P
DQ186648.1 Homo sapiens p53 beta isoform (TP53) mRNA, complete cds P
DQ263704.1 Homo sapiens tumor protein p53 (TP53) mRNA, complete cds P
DQ286964.1 Homo sapiens p53 protein (TP53) mRNA, complete cds, alternatively spliced P
DQ191317.1 Homo sapiens p53 protein (TP53) mRNA, complete cds, alternatively spliced P
DQ401704.1 Homo sapiens p53deltaEx4 mRNA, partial cds P
AF307851.1 Homo sapiens p53 protein mRNA, complete cds PA
AM076972.1 Homo sapiens partial mRNA for tumor protein p53 mutant form (TP53 gene), classical Hodgkin Lymphoma cell line L1236 P
AM076971.1 Homo sapiens partial mRNA for tumor protein p53 mutant form (TP53 gene), classical Hodgkin Lymphoma cell line HDLM-2 P
AM076970.1 Homo sapiens partial mRNA for tumor protein p53 mutant form (TP53 gene), classical Hodgkin Lymphoma cell line L428 P
DQ485152.1 Homo sapiens cell-line Hec50co truncated p53 splice variant (TP53) mRNA, partial cds, aberrantly spliced
BC003596.1 Homo sapiens tumor protein p53, mRNA (cDNA clone MGC:646 IMAGE:3544714), complete cds PA
DQ648887.1 Homo sapiens p53-Ex10 isoform (TP53) mRNA, partial cds, alternatively spliced
DQ648886.1 Homo sapiens p53+ins9a (TP53) mRNA, 3' UTR, alternatively spliced
DQ648885.1 Homo sapiens p53-Ex(2-4) isoform (TP53) mRNA, partial cds, alternatively spliced P
DQ648884.1 Homo sapiens p53-Ex4 isoform (TP53) mRNA, partial cds, alternatively spliced P
AK225838.1 Homo sapiens mRNA for Cellular tumor antigen p53 variant, clone: FCC127A11 P
M14694.1 Human p53 cellular tumor antigen mRNA, complete cds P
M14695.1 Human p53 cellular tumor antigen mRNA, complete cds P
EF101869.1 Homo sapiens cell-line HDLM2 nonfunctional tumor suppressor p53 (TP53) mRNA, complete cds P
EF101868.1 Homo sapiens cell-line L1236 nonfunctional tumor suppressor p53 (TP53) mRNA, complete cds P
EF101867.1 Homo sapiens cell-line L428 nonfunctional tumor suppressor p53 (TP53) mRNA, complete cds P
X01405.1 Human mRNA fragment for phosphoprotein p53 P
AK312568.1 Homo sapiens cDNA, FLJ92943, Homo sapiens tumor protein p53 (Li-Fraumeni syndrome) (TP53), mRNA P
NM_001126117.1 Homo sapiens tumor protein p53 (TP53), transcript variant 7, mRNA PA
NM_001126116.1 Homo sapiens tumor protein p53 (TP53), transcript variant 6, mRNA PA
NM_001126115.1 Homo sapiens tumor protein p53 (TP53), transcript variant 5, mRNA PA
NM_001126114.2 Homo sapiens tumor protein p53 (TP53), transcript variant 3, mRNA PA
NM_001126113.2 Homo sapiens tumor protein p53 (TP53), transcript variant 4, mRNA PA
NM_001126112.2 Homo sapiens tumor protein p53 (TP53), transcript variant 2, mRNA PA
AK297927.1 Homo sapiens cDNA FLJ54299 complete cds, highly similar to Cellular tumor antigen p53 P
AK297462.1 Homo sapiens cDNA FLJ54297 complete cds, highly similar to Cellular tumor antigen p53 P
FJ207420.1 Homo sapiens mutant p53 mRNA, complete cds PA
X60020.1 Human mRNA for mutated p53 transformation suppressor gene P
X60019.1 Human mRNA for mutated p53 transformation suppressor gene P
X60018.1 Human mRNA for mutated p53 transformation suppressor gene P
X60017.1 Human mRNA for mutated p53 transformation suppressor gene P
X60016.1 Human mRNA for mutated p53 transformation suppressor gene P
X60015.1 Human mRNA for mutated p53 transformation suppressor gene P
X60014.1 Human mRNA for mutated p53 transformation suppressor gene P
X60013.1 Human mRNA for mutated p53 transformation suppressor gene P
X60011.1 Human mRNA for mutated p53 transformation suppressor gene P
X60012.1 Human mRNA for mutated p53 transformation suppressor gene P
X60010.1 Human mRNA for mutated p53 transformation suppressor gene P
X02469.1 Human mRNA for p53 cellular tumor antigen P
S66666.1 p53=tumor suppressor {alternatively spliced, exon 9-10} [human, Molt-4, T-lymphoblastic leukemia cell line, mRNA PartialMutant, 160 nt]
AB082923.1 Homo sapiens mRNA for P53, complete cds PA
NM_001126118.1 Homo sapiens tumor protein p53 (TP53), transcript variant 8, mRNA PA
JN900492.1 Homo sapiens tumor suppressor TP53 (TP53) mRNA, complete cds, alternatively spliced PA
NM_001276699.1 Homo sapiens tumor protein p53 (TP53), transcript variant 7, mRNA A
NM_001276698.1 Homo sapiens tumor protein p53 (TP53), transcript variant 6, mRNA A
NM_001276697.1 Homo sapiens tumor protein p53 (TP53), transcript variant 5, mRNA A
NM_001276761.1 Homo sapiens tumor protein p53 (TP53), transcript variant 2, mRNA A
NM_001276760.1 Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA A
NM_001276696.1 Homo sapiens tumor protein p53 (TP53), transcript variant 3, mRNA A
NM_001276695.1 Homo sapiens tumor protein p53 (TP53), transcript variant 4, mRNA A

EST sequences (10 of 569) [Show all sequences]

BX111932.1 Clone IMAGp998C0576_;_IMAGE:24415 brain A
CB134750.1 Clone L5HLK1-31-F08 liver 5' read P
CB116410.1 Clone L6ChoCK0-14-C04 liver 5' read
CB138393.1 Clone L15CKK1-29-B07 liver 5' read P
AA947588.1 Clone IMAGE:1508462 mixed 3' read
AI243172.1 Clone IMAGE:1847162 mixed 3' read P
AI335640.1 Clone IMAGE:1948557 uncharacterized tissue 3' read A
AI380242.1 Clone IMAGE:2106918 uncharacterized tissue 3' read A
AI539544.1 Clone IMAGE:2189478 uterus 3' read A
AU280602.1 Clone N1ESE2002780 uncharacterized tissue 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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