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UGID:231466     UniGene Hs.436429     Homo sapiens (human)   PTPN3
Protein tyrosine phosphatase, non-receptor type 3 (PTPN3)

Human protein-coding gene PTPN3. Represented by 316 ESTs from 136 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 231466 - Hs.436429]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002820.3 PTPN3 gene product H. sapiens 100.0 912
XP_520179.2 PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform 3 P. troglodytes 99.8 912
NP_035337.2 Ptpn3 gene product M. musculus 94.3 912
NP_001085662.1 protein tyrosine phosphatase, non-receptor type 3 X. laevis 76.5 919
XP_687930.4 PREDICTED: protein tyrosine phosphatase, non-receptor type 3 D. rerio 63.0 844
NP_741112.1 Protein PTP-1, isoform c C. elegans 57.3 410
NP_612031.3 ptpmeg, isoform G D. melanogaster 49.2 331
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_001107076.2 PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform 1 M. mulatta 98.9 927
XP_003911436.1 PREDICTED: tyrosine-protein phosphatase non-receptor type 3 P. anubis 98.7 927

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; mixed; uncharacterized tissue; kidney; heart; thyroid; trachea; lung; placenta; uterus; testis; prostate; mammary gland; larynx; skin; muscle; vascular; thymus; pancreas; bladder; adrenal gland; liver; cervix; parathyroid; bone; nerve; connective tissue; ascites; mouth; eye; blood; embryonic tissue; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q31
UniSTS entry: Chr 9 RH78381
UniSTS entry: Chr 9 G32870
UniSTS entry: Chr 9 STS-W15441
UniSTS entry: Chr 9 A009V09
UniSTS entry: Chr 9 D9S1760 [Map Viewer]
UniSTS entry: Chr 9 RH91146
UniSTS entry: Chr 9 D9S1693
UniSTS entry: Chr 9 PTPN3_2445
UniSTS entry: Chr 10 D9S58
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

BX648735.1 Homo sapiens mRNA; cDNA DKFZp686N1128 (from clone DKFZp686N1128) PA
BX648253.1 Homo sapiens mRNA; cDNA DKFZp686B07115 (from clone DKFZp686B07115) PA
NM_002829.3 Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1, mRNA P
CR749204.1 Homo sapiens mRNA; cDNA DKFZp686N0569 (from clone DKFZp686N0569) PA
BC126117.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3, mRNA (cDNA clone MGC:161395 IMAGE:8991833), complete cds P
AK308349.1 Homo sapiens cDNA, FLJ98297 P
BC033716.1 Homo sapiens, clone IMAGE:4452690, mRNA, partial cds PA
AK096975.1 Homo sapiens cDNA FLJ39656 fis, clone SMINT2005956
S39392.1 Homo sapiens protein tyrosine phosphatase mRNA, partial cds P
BC143848.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3, mRNA (cDNA clone MGC:177380 IMAGE:9052363), complete cds P
AK316118.1 Homo sapiens cDNA, FLJ79017 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type3 (EC 3.1.3.48) P
AK316066.1 Homo sapiens cDNA, FLJ78965 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) P
AK304434.1 Homo sapiens cDNA FLJ53589 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type3 (EC 3.1.3.48) P
AK303608.1 Homo sapiens cDNA FLJ52384 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) P
AK296388.1 Homo sapiens cDNA FLJ59556 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type3 (EC 3.1.3.48) P
AK296265.1 Homo sapiens cDNA FLJ50413 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type3 (EC 3.1.3.48) P
NM_001145372.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 6, mRNA P
NM_001145371.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 5, mRNA P
NM_001145370.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 4, mRNA P
NM_001145369.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 3, mRNA P
NM_001145368.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 2, mRNA P
NR_026918.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 7, non-coding RNA P
M64572.1 Human protein tyrosine phosphatase mRNA, complete cds P

EST sequences (10 of 316) [Show all sequences]

AA970010.1 Clone IMAGE:1581356 mixed 3' read
AA897751.1 Clone IMAGE:1504307 mixed 3' read
AI001902.1 Clone IMAGE:1619405 testis 3' read
AI025939.1 Clone IMAGE:1645885 parathyroid 3' read A
AI040327.1 Clone IMAGE:1667597 parathyroid 3' read A
AI074453.1 Clone IMAGE:1673704 mixed 3' read A
AI078025.1 Clone IMAGE:1674425 mixed 3' read
AI091104.1 Clone IMAGE:1689786 mixed 3' read
AI128676.1 Clone IMAGE:1691191 heart 3' read
BX099980.1 Clone IMAGp998A02402_;_IMAGE:206857 mixed


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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