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UGID:231442     UniGene Hs.436405     Homo sapiens (human)   IDH3B
Isocitrate dehydrogenase 3 (NAD+) beta (IDH3B)

Human protein-coding gene IDH3B. Represented by 947 ESTs from 329 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 231442 - Hs.436405]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001114288.1 PREDICTED: isocitrate dehydrogenase [NAD] subunit beta, mitochondrial-like isoform 3 M. mulatta 100.0 384
XP_003905027.1 PREDICTED: isocitrate dehydrogenase [NAD] subunit beta, mitochondrial P. anubis 100.0 384
XP_001157460.1 PREDICTED: isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform 10 P. troglodytes 100.0 384
NP_008830.2 IDH3B gene product H. sapiens 100.0 384
NP_570954.1 isocitrate dehydrogenase 3, beta subunit M. musculus 97.9 383
NP_001085395.1 isocitrate dehydrogenase 3 (NAD+) beta X. laevis 92.3 375
NP_001002157.1 idh3b gene product D. rerio 92.2 381
NP_510362.1 Protein IDHB-1 C. elegans 73.3 370
NP_651000.1 CG6439, isoform A D. melanogaster 71.2 357
XP_001694857.1 isocitrate dehydrogenase, NAD-dependent C. reinhardtii 62.2 348
NP_568113.1 Isocitrate dehydrogenase [NAD] catalytic subunit 5 A. thaliana 58.8 370
XP_964931.2 isocitrate dehydrogenase subunit 1, mitochondrial precursor N. crassa 56.6 376
NP_014361.1 isocitrate dehydrogenase (NAD(+)) IDH1 S. cerevisiae 53.9 356
Other hits (2 of 67) [Show all]SpeciesId(%)Len(aa)
NP_001038040.1 IDH3B gene product S. scrofa 99.2 384
XP_001497117.1 PREDICTED: isocitrate dehydrogenase [NAD] subunit beta, mitochondrial-like isoform 1 E. caballus 99.0 384

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; lung; ascites; liver; skin; intestine; tonsil; eye; testis; blood; uncharacterized tissue; embryonic tissue; mixed; uterus; kidney; adipose tissue; thymus; prostate; spleen; ovary; cervix; muscle; larynx; lymph node; heart; mammary gland; stomach; thyroid; pancreas; lymph; adrenal gland; nerve; connective tissue; bone; mouth; bladder; pharynx; epididymis; salivary gland; bone marrow; vascular; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20p13
UniSTS entry: Chr 20 D20S1022 [Map Viewer]
UniSTS entry: Chr 20 MARC_26128-26129:1030370563:1
UniSTS entry: Chr 20 RH74
UniSTS entry: Chr 20 SGC32750 [Map Viewer]
UniSTS entry: Chr 20 RH78746 [Map Viewer]
UniSTS entry: Chr 20 RH78034 [Map Viewer]
UniSTS entry: Chr 20 WI-16193 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_174855.2 Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA PA
AL050094.1 Homo sapiens mRNA; cDNA DKFZp586P0718 (from clone DKFZp586P0718); partial cds PA
BX647393.1 Homo sapiens mRNA; cDNA DKFZp686K18144 (from clone DKFZp686K18144) PA
NM_006899.3 Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
BC001960.1 Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta, mRNA (cDNA clone MGC:903 IMAGE:3536921), complete cds PA
AK315641.1 Homo sapiens cDNA, FLJ96729, Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B),nuclear gene encoding mitochondrial protein, transcript variant 1,mRNA P
AK309488.1 Homo sapiens cDNA, FLJ99529 P
AK300485.1 Homo sapiens cDNA FLJ57795 complete cds, highly similar to Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor (EC 1.1.1.41) P
BC019037.2 Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta, mRNA (cDNA clone IMAGE:4591114) PA
U87972.1 Human NAD+-isocitrate dehydrogenase mRNA, partial cds P
NM_001258384.1 Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), nuclear gene encoding mitochondrial protein, transcript variant 4, mRNA P

EST sequences (10 of 947) [Show all sequences]

AA976445.1 Clone IMAGE:1589890 kidney 3' read A
R15323.1 Clone IMAGE:29794 brain 5' read
AA993092.1 Clone IMAGE:1625060 embryonic tissue 3' read A
AA994485.1 Clone IMAGE:1626567 mixed 3' read PA
AI001963.1 Clone IMAGE:1613442 uncharacterized tissue 3' read A
AI005192.1 Clone IMAGE:1632189 mammary gland 3' read PA
AI018456.1 Clone IMAGE:1641983 testis 3' read A
AI024081.1 Clone IMAGE:1642890 testis 3' read A
AI054195.1 Clone IMAGE:1862318 ovary 3' read A
AI126744.1 Clone IMAGE:1706915 heart 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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