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UGID:230808     UniGene Hs.435771     Homo sapiens (human)   API5
Apoptosis inhibitor 5 (API5)

Human protein-coding gene API5. Represented by 1090 ESTs from 293 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 230808 - Hs.435771]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001114497.2 PREDICTED: apoptosis inhibitor 5 isoform 5 M. mulatta 100.0 523
XP_001156398.2 PREDICTED: apoptosis inhibitor 5 isoform 4 P. troglodytes 100.0 523
NP_001136402.1 API5 gene product H. sapiens 100.0 523
XP_003910060.1 PREDICTED: apoptosis inhibitor 5-like P. anubis 100.0 449
XP_001488315.2 PREDICTED: apoptosis inhibitor 5 isoform 1 E. caballus 99.8 523
NP_001120851.1 Api5 gene product R. norvegicus 99.8 503
XP_856598.1 PREDICTED: apoptosis inhibitor 5 isoform 2 C. lupus familiaris 99.6 523
XP_003122904.1 PREDICTED: apoptosis inhibitor 5 isoform 1 S. scrofa 99.6 523
NP_031492.2 Api5 gene product M. musculus 99.6 503
XP_002709107.1 PREDICTED: apoptosis inhibitor 5 isoform 1 O. cuniculus 99.6 503
NP_001080226.1 apoptosis inhibitor 5-B X. laevis 89.5 522
NP_955834.2 apoptosis inhibitor 5 D. rerio 88.2 525
NP_509585.1 Protein TBB-4 C. elegans 88.0 83
NP_477454.1 Aac11 D. melanogaster 51.3 532
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_004016465.1 PREDICTED: apoptosis inhibitor 5 isoform 1 O. aries 99.4 523
NP_001137555.1 apoptosis inhibitor 5 B. taurus 99.4 503

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; trachea; uterus; embryonic tissue; kidney; heart; esophagus; thymus; mixed; mouth; nerve; pituitary gland; ear; stomach; placenta; lung; bladder; blood; adrenal gland; skin; intestine; liver; prostate; connective tissue; uncharacterized tissue; pancreas; lymph node; ovary; salivary gland; eye; spleen; bone; mammary gland; vascular; pharynx; cervix; muscle; thyroid; parathyroid; bone marrow; lymph; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p11.2
UniSTS entry: Chr 11 RH11873
UniSTS entry: Chr X RH65627
UniSTS entry: Chr 11 SHGC-110333
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BT007093.1 Homo sapiens apoptosis inhibitor 5 mRNA, complete cds P
Y15906.1 Homo sapiens mRNA for XAGL protein PA
NM_006595.3 Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 2, mRNA PA
AY311389.1 Homo sapiens migration-inducing protein MIG8 mRNA, complete cds PA
AF229254.1 Homo sapiens clone FIF 504 fibroblast growth factor 2-interacting factor (API5) mRNA, complete cds P
AF229253.1 Homo sapiens clone FIF N1 fibroblast growth factor 2-interacting factor (API5) mRNA, partial cds.; alternatively spliced PA
BC017709.1 Homo sapiens apoptosis inhibitor 5, mRNA (cDNA clone MGC:21216 IMAGE:4419401), complete cds PA
AK294724.1 Homo sapiens cDNA FLJ53886 complete cds, highly similar to Apoptosis inhibitor 5 PA
AK293303.1 Homo sapiens cDNA FLJ52148 complete cds, highly similar to Apoptosis inhibitor 5 P
AK299288.1 Homo sapiens cDNA FLJ61353 complete cds, highly similar to Apoptosis inhibitor 5 P
AK304157.1 Homo sapiens cDNA FLJ51754 complete cds, highly similar to Apoptosis inhibitor 5 PA
NM_001142931.1 Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 3, mRNA PA
NM_001142930.1 Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 1, mRNA PA
NM_001243747.1 Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 5, mRNA PA
NR_024625.1 Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 4, non-coding RNA PA

EST sequences (10 of 1090) [Show all sequences]

R14048.1 Clone IMAGE:26995 brain 5' read
R14210.1 Clone IMAGE:28609 brain 5' read P
R14315.1 Clone IMAGE:28682 brain 5' read
AA962363.1 Clone IMAGE:1580079 mixed 3' read A
AA972513.1 Clone IMAGE:1575745 intestine 3' read A
AA971731.1 Clone IMAGE:1584614 lung 3' read A
R15915.1 Clone IMAGE:53234 brain 5' read P
R14649.1 Clone IMAGE:35616 brain 5' read P
AA991911.1 Clone IMAGE:1611326 uncharacterized tissue 3' read A
AI002228.1 Clone IMAGE:1601382 lung 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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