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UGID:223647     UniGene Hs.418497     Homo sapiens (human)   GC
Group-specific component (vitamin D binding protein) (GC)

Human protein-coding gene GC. Represented by 425 ESTs from 58 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 223647 - Hs.418497]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001191236.1 GC gene product H. sapiens 100.0 492
XP_003310390.1 PREDICTED: vitamin D-binding protein isoform 2 P. troglodytes 100.0 473
NP_032122.1 Gc gene product M. musculus 84.0 474
NP_001088335.1 group-specific component (vitamin D binding protein) precursor X. laevis 51.7 325
NP_001002568.1 gc gene product D. rerio 47.3 167
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001104833.2 PREDICTED: vitamin D-binding protein M. mulatta 96.5 489
XP_003898836.1 PREDICTED: vitamin D-binding protein isoform 1 P. anubis 96.4 473

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; mixed; pancreas; mammary gland; blood; kidney; heart; intestine; connective tissue; embryonic tissue; ovary; uncharacterized tissue; muscle; spleen; lung
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q12-q13
UniSTS entry: Chr 4 SHGC-59541
UniSTS entry: Chr 4 RH68432
UniSTS entry: G34524
UniSTS entry: Chr 4 SHGC-24721 [Map Viewer]
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC057228.1 Homo sapiens group-specific component (vitamin D binding protein), mRNA (cDNA clone MGC:61910 IMAGE:4767205), complete cds PA
NM_000583.3 Homo sapiens group-specific component (vitamin D binding protein) (GC), transcript variant 1, mRNA PA
AK223458.1 Homo sapiens mRNA for vitamin D-binding protein precursor variant, clone: FCC115E11 PA
X03178.1 Human mRNA for group-specific component (GC) P
AK290827.1 Homo sapiens cDNA FLJ78164 complete cds, highly similar to Homo sapiens group-specific component (vitamin D binding protein), mRNA PA
AK312971.1 Homo sapiens cDNA, FLJ93431 P
AK315853.1 Homo sapiens cDNA, FLJ79502 complete cds, highly similar to Vitamin D-binding protein precursor PA
AK309595.1 Homo sapiens cDNA, FLJ99636 PA
BC022310.1 Homo sapiens cDNA clone IMAGE:4767884, containing frame-shift errors PA
NM_001204307.1 Homo sapiens group-specific component (vitamin D binding protein) (GC), transcript variant 3, mRNA PA
NM_001204306.1 Homo sapiens group-specific component (vitamin D binding protein) (GC), transcript variant 2, mRNA PA

EST sequences (10 of 425) [Show all sequences]

AA968433.1 Clone IMAGE:1580160 mixed 3' read PA
AA974692.1 Clone IMAGE:1578256 mixed 3' read A
AI032548.1 Clone IMAGE:1654799 mixed 3' read A
AI034363.1 Clone IMAGE:1656899 mixed 3' read PA
AI034365.1 Clone IMAGE:1656903 mixed 3' read PA
AI076291.1 Clone IMAGE:1673554 mixed 3' read PA
AI092243.1 Clone IMAGE:1691161 heart 3' read A
AI097273.1 Clone IMAGE:1707206 heart 3' read PA
CB068836.1 Clone IMAGE:6554539 pancreas 3' read PA
CB069002.1 Clone IMAGE:6554539 pancreas 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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