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UGID:221112     UniGene Hs.408614     Homo sapiens (human)   ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (ST8SIA1)

Human protein-coding gene ST8SIA1. Represented by 86 ESTs from 48 cDNA libraries. Corresponds to reference sequence NM_003034.3. [UniGene 221112 - Hs.408614]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001099511.1 PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform 1 M. mulatta 100.0 355
XP_003906151.1 PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase P. anubis 100.0 355
NP_001032380.1 ST8SIA1 gene product P. troglodytes 100.0 355
NP_003025.1 ST8SIA1 gene product H. sapiens 100.0 355
NP_035504.2 St8sia1 gene product M. musculus 94.7 354
NP_001083088.1 alpha-N-acetylneuraminide alpha-2,8-sialyltransferase X. laevis 74.6 323
XP_002661434.1 PREDICTED: alpha-2,8-sialyltransferase ST8Sia I-like D. rerio 69.9 316
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_534865.2 PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform 1 C. lupus familiaris 99.4 355
XP_003355598.1 PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase-like S. scrofa 99.4 157

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; parathyroid; muscle; lung; mammary gland; testis; embryonic tissue; placenta; ovary; skin; pancreas; kidney; ear; stomach; trachea; mixed; prostate; vascular; heart; salivary gland; mouth; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p12.1-p11.2
UniSTS entry: Chr 12 STS-X77922
UniSTS entry: Chr 12 RH69610 [Map Viewer]
UniSTS entry: Chr 12 SHGC-12597 [Map Viewer]
UniSTS entry: Chr 12 SHGC-132098
UniSTS entry: Chr 1 D17S610
UniSTS entry: Chr 12 D12S1688 [Map Viewer]
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 12 SHGC-151275
UniSTS entry: Chr 12 SHGC-152564
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BC046158.1 Homo sapiens ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1, mRNA (cDNA clone IMAGE:5557348), complete cds PA
NM_003034.3 Homo sapiens ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (ST8SIA1), mRNA PA
AY569975.1 Homo sapiens Sat-2 short mRNA, complete cds; alternatively spliced P
L43494.1 Human ganglioside-specific alpha-2,8-polysialyltransferase (GD3/GT3ST) mRNA, complete cds P
BC117285.1 Homo sapiens ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1, mRNA (cDNA clone MGC:150894 IMAGE:40125836), complete cds P
BC126162.1 Homo sapiens ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1, mRNA (cDNA clone MGC:161440 IMAGE:8991878), complete cds P
L32867.1 Homo sapiens alpha 2,8-sialyltransferase mRNA, complete cds P
EU041716.1 Homo sapiens ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 variant (ST8SIA1) mRNA, complete cds, alternatively spliced PA
AK290941.1 Homo sapiens cDNA FLJ77944 complete cds, highly similar to H.sapiens GD3 synthase mRNA P
AK315340.1 Homo sapiens cDNA, FLJ96382, Homo sapiens sialyltransferase 8A (alpha-N-acetylneuraminate:alpha-2,8-sialyltransferase, GD3 synthase) (SIAT8A), mRNA P
AK297310.1 Homo sapiens cDNA FLJ51992 complete cds, highly similar to Alpha-N-acetylneuraminidealpha-2,8-sialyltransferase (EC 2.4.99.8) P
X77922.1 H.sapiens GD3 synthase mRNA PA
BC031081.1 Homo sapiens ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1, mRNA (cDNA clone IMAGE:5275961), containing frame-shift errors PA
AF088002.1 Homo sapiens full length insert cDNA clone YY47A07 A
D26360.1 Homo sapiens mRNA for alpha 2,8-sialyltransferase, complete cds P

EST sequences (10 of 86) [Show all sequences]

AI028044.1 Clone IMAGE:1649550 parathyroid 3' read A
AI051537.1 Clone IMAGE:1659117 embryonic tissue 3' read A
CB068363.1 Clone IMAGE:6365227 pancreas 3' read
BX104473.1 Clone IMAGp998N19728_;_IMAGE:322002 parathyroid P
CB177261.1 Clone IMAGE:6365227 pancreas 5' read
AI291051.1 Clone IMAGE:1881844 lung 3' read A
AI765214.1 Clone IMAGE:2398883 kidney 3' read P
CB410969.1 ear
Z19468.1 Clone 31B08 muscle
BX340093.2 Clone CS0DI081YP04 placenta 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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