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UGID:220727     UniGene Hs.407604     Homo sapiens (human)   MED14
Mediator complex subunit 14 (MED14)

Human protein-coding gene MED14. Represented by 447 ESTs from 191 cDNA libraries. Corresponds to reference sequence NM_004229.3. [UniGene 220727 - Hs.407604]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003917641.1 PREDICTED: mediator of RNA polymerase II transcription subunit 14 P. anubis 100.0 1453
NP_004220.2 MED14 gene product H. sapiens 100.0 1453
XP_001085867.1 PREDICTED: mediator of RNA polymerase II transcription subunit 14 M. mulatta 99.9 1453
XP_003317475.2 PREDICTED: LOW QUALITY PROTEIN: mediator of RNA polymerase II transcription subunit 14 P. troglodytes 99.9 1450
XP_538001.2 PREDICTED: mediator of RNA polymerase II transcription subunit 14 isoform 1 C. lupus familiaris 99.8 1453
XP_003135073.1 PREDICTED: mediator of RNA polymerase II transcription subunit 14 S. scrofa 99.6 1453
NP_001041673.1 Med14 gene product M. musculus 98.6 1458
NP_997930.2 mediator of RNA polymerase II transcription subunit 14 D. rerio 87.1 1421
NP_612041.2 mediator complex subunit 14, isoform A D. melanogaster 55.0 1397
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
NP_001193960.1 mediator of RNA polymerase II transcription subunit 14 B. taurus 99.5 1451
XP_002719882.1 PREDICTED: mediator complex subunit 14 O. cuniculus 99.4 1332

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; brain; embryonic tissue; placenta; testis; bone; esophagus; heart; lung; mammary gland; mouth; prostate; blood; pancreas; uterus; lymph node; intestine; kidney; muscle; thymus; liver; vascular; thyroid; stomach; trachea; bladder; epididymis; adrenal gland; eye; mixed; ovary; skin; cervix; bone marrow; lymph; ascites; connective tissue; larynx; spleen; spinal cord; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp11.4
UniSTS entry: Chr X STS-H16735
UniSTS entry: Chr X WI-15558 [Map Viewer]
UniSTS entry: Chr X DXS7582 [Map Viewer]
UniSTS entry: Chr X G06191
UniSTS entry: Chr X STS-AA011019 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AB006651.1 Homo sapiens EXLM1 mRNA, complete cds P
AF070563.1 Homo sapiens clone 24555 mRNA sequence P
AJ012077.1 Homo sapiens mRNA for EXLM1 protein, 3' end P
AF104256.1 Homo sapiens transcriptional co-activator CRSP150 (CRSP150) mRNA, complete cds P
NM_004229.3 Homo sapiens mediator complex subunit 14 (MED14), mRNA PA
AF135802.1 Homo sapiens thyroid hormone receptor-associated protein complex component TRAP170 mRNA, complete cds P
BC098377.1 Homo sapiens mediator complex subunit 14, mRNA (cDNA clone MGC:104513 IMAGE:30527948), complete cds PA
AF304448.1 Homo sapiens vitamin D receptor-interacting protein complex component DRIP150 (DRIP150) mRNA, complete cds P
BC132672.1 Homo sapiens mediator complex subunit 14, mRNA (cDNA clone MGC:164303 IMAGE:40146694), complete cds P
BC132674.1 Homo sapiens mediator complex subunit 14, mRNA (cDNA clone MGC:164305 IMAGE:40146696), complete cds P
AK293070.1 Homo sapiens cDNA FLJ77399 complete cds, highly similar to Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa (CRSP2), mRNA P
AK308871.1 Homo sapiens cDNA, FLJ98912 P
BC144231.1 Homo sapiens cDNA clone IMAGE:9052751, containing frame-shift errors P

EST sequences (10 of 447) [Show all sequences]

R14275.1 Clone IMAGE:28444 brain 5' read
R18948.1 Clone IMAGE:33194 brain 5' read
AI096334.1 Clone IMAGE:1697890 uterus 3' read
AI147882.1 Clone IMAGE:1698141 uterus 3' read
AI168429.1 Clone IMAGE:1509351 mixed 3' read A
AI263090.1 Clone IMAGE:2028860 kidney 3' read A
CB141633.1 Clone L15CKK1-31-C10 liver 5' read P
CB142407.1 Clone L15CKK1-23-A09 liver 5' read P
CB140914.1 Clone L15CKK1-27-F04 liver 5' read P
AI282836.1 Clone IMAGE:1960723 esophagus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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