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UGID:220500     UniGene Hs.407122     Homo sapiens (human)   TMPRSS11B
Transmembrane protease, serine 11B (TMPRSS11B)

Human protein-coding gene TMPRSS11B. Represented by 23 ESTs from 9 cDNA libraries. EST representation biased toward esophagus; esophageal tumor. Corresponds to reference sequence NM_182502.3. [UniGene 220500 - Hs.407122]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_872308.2 transmembrane protease serine 11B H. sapiens 100.0 415
NP_795998.2 Tmprss11bnl gene product M. musculus 51.9 415
Other hits (2 of 12) [Show all]SpeciesId(%)Len(aa)
XP_517263.2 PREDICTED: transmembrane protease serine 11B P. troglodytes 98.8 415
XP_003898880.1 PREDICTED: transmembrane protease serine 11B P. anubis 95.0 415

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: esophagus [show more like this]
esophageal tumor [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: esophagus; pharynx; mouth; larynx; cervix; bronchus; muscle
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q13.2
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

BX537945.1 Homo sapiens mRNA; cDNA DKFZp686A2412 (from clone DKFZp686A2412); complete cds PA
NM_182502.3 Homo sapiens transmembrane protease, serine 11B (TMPRSS11B), mRNA PA
BC126195.1 Homo sapiens transmembrane protease, serine 11B, mRNA (cDNA clone MGC:161473 IMAGE:8991911), complete cds P
AK290904.1 Homo sapiens cDNA FLJ75359 complete cds P
AK310210.1 Homo sapiens cDNA, FLJ17252 P
AL833167.1 Homo sapiens mRNA; cDNA DKFZp686L1818 (from clone DKFZp686L1818); complete cds PA

EST sequences (10 of 23) [Show all sequences]

AW238624.1 Clone IMAGE:2741770 mouth 3' read A
AW263856.1 Clone IMAGE:2741940 mouth 3' read A
BF188818.1 Clone HBEC-71 bronchus
BF354411.1 pharynx P
BF354474.1 pharynx P
BF355951.1 larynx
DA669435.1 Clone NESOP2002398 esophagus 5' read P
DA422237.1 Clone CERVX2002127 cervix 5' read P
DA422442.1 Clone CERVX2002367 cervix 5' read P
DB012553.1 Clone TESOP2000924 esophagus 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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