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UGID:219875     UniGene Hs.406013     Homo sapiens (human)   KRT18
Keratin 18 (KRT18)

Human protein-coding gene KRT18. Represented by 3922 ESTs from 443 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 219875 - Hs.406013]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_509083.2 PREDICTED: keratin, type I cytoskeletal 18 P. troglodytes 100.0 429
NP_954657.1 KRT18 gene product H. sapiens 100.0 429
XP_001100009.1 PREDICTED: keratin, type I cytoskeletal 18 isoform 1 M. mulatta 99.8 429
XP_003906487.1 PREDICTED: keratin, type I cytoskeletal 18 P. anubis 99.8 429
NP_034794.2 Krt18 gene product M. musculus 93.4 422
NP_001091276.1 uncharacterized protein LOC100037084 X. laevis 93.4 422
NP_848524.1 krt18 gene product D. rerio 65.0 426
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003126228.3 PREDICTED: keratin, type I cytoskeletal 18 S. scrofa 93.8 389
XP_002711493.1 PREDICTED: keratin 18-like O. cuniculus 93.7 430

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; pancreas; placenta; embryonic tissue; mammary gland; liver; lung; uterus; prostate; ovary; eye; mixed; stomach; esophagus; skin; kidney; ascites; cervix; uncharacterized tissue; amniotic fluid; thyroid; brain; bone marrow; testis; bone; pituitary gland; bladder; larynx; salivary gland; spleen; tonsil; lymph node; heart; mouth; blood; adipose tissue; epididymis; lymph; umbilical cord; connective tissue; vascular; muscle; peritoneum; parathyroid; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13
UniSTS entry: Chr 11 SHGC-11808
UniSTS entry: Chr 12 PMC17321P1
UniSTS entry: Chr 12 G66248
UniSTS entry: Chr 3 STS-N95819
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK129587.1 Homo sapiens cDNA FLJ26076 fis, clone RCT02495, highly similar to Keratin, type I cytoskeletal 18 P
NM_000224.2 Homo sapiens keratin 18 (KRT18), transcript variant 1, mRNA PA
NM_199187.1 Homo sapiens keratin 18 (KRT18), transcript variant 2, mRNA PA
BC072017.1 Homo sapiens keratin 18, mRNA (cDNA clone MGC:88728 IMAGE:6251574), complete cds PA
BT019412.1 Homo sapiens keratin 18 mRNA, complete cds P
AK223093.1 Homo sapiens mRNA for keratin 18 variant, clone: KAT03780 PA
AY762101.1 Homo sapiens cell proliferation-inducing protein 46 mRNA, complete cds P
BC000698.2 Homo sapiens keratin 18, mRNA (cDNA clone MGC:1549 IMAGE:3349315), complete cds PA
BC000180.2 Homo sapiens keratin 18, mRNA (cDNA clone MGC:5055 IMAGE:2984862), complete cds PA
BC004253.1 Homo sapiens keratin 18, mRNA (cDNA clone MGC:10564 IMAGE:3631540), complete cds PA
BC008636.1 Homo sapiens keratin 18, mRNA (cDNA clone MGC:9348 IMAGE:3463780), complete cds PA
BC009754.2 Homo sapiens keratin 18, mRNA (cDNA clone IMAGE:3835032), partial cds PA
BC020982.1 Homo sapiens keratin 18, mRNA (cDNA clone MGC:9716 IMAGE:3850724), complete cds PA
AK313988.1 Homo sapiens cDNA, FLJ94640, highly similar to Homo sapiens keratin 18 (KRT18), mRNA P
AK308506.1 Homo sapiens cDNA, FLJ98547 P
L32537.1 Homo sapiens (clone XP6G6B) mRNA, partial EST
X12881.1 Human mRNA for cytokeratin 18 P
X12883.1 Human mRNA for cytokeratin 18 P
X12876.1 Human mRNA fragment for cytokeratin 18 P

EST sequences (10 of 3922) [Show all sequences]

AA954854.1 Clone IMAGE:1576218 intestine 3' read P
AA960815.1 Clone IMAGE:1552220 uncharacterized tissue 3' read P
AA962695.1 Clone IMAGE:1575457 intestine 3' read A
AA970753.1 Clone IMAGE:1576456 intestine 3' read PA
AA976426.1 Clone IMAGE:1589862 kidney 3' read PA
AA978070.1 Clone IMAGE:1590858 kidney 3' read P
AA989458.1 Clone IMAGE:1607743 mammary gland 3' read PA
AA994309.1 Clone IMAGE:1631270 mammary gland 3' read PA
AA902819.1 Clone IMAGE:1519155 uncharacterized tissue 3' read PA
AA946716.1 Clone IMAGE:1421039 intestine 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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