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UGID:219579     UniGene Hs.405610     Homo sapiens (human)   MBD1
Methyl-CpG binding domain protein 1 (MBD1)

Human protein-coding gene MBD1. Represented by 594 ESTs from 252 cDNA libraries. Corresponds to 14 reference sequences (different isoforms). [UniGene 219579 - Hs.405610]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003315957.1 PREDICTED: methyl-CpG-binding domain protein 1 isoform 8 P. troglodytes 100.0 655
NP_001191065.1 MBD1 gene product H. sapiens 100.0 654
XP_003914425.1 PREDICTED: methyl-CpG-binding domain protein 1 isoform 1 P. anubis 99.8 629
XP_001098362.2 PREDICTED: methyl-CpG-binding domain protein 1-like isoform 1 M. mulatta 99.7 629
NP_038622.2 Mbd1 gene product M. musculus 75.9 569
Other hits (2 of 9) [Show all]SpeciesId(%)Len(aa)
XP_003121489.2 PREDICTED: methyl-CpG-binding domain protein 1 S. scrofa 92.3 535
XP_537343.3 PREDICTED: methyl-CpG-binding domain protein 1 C. lupus familiaris 92.0 633

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; uncharacterized tissue; eye; mouth; vascular; placenta; lung; thymus; uterus; embryonic tissue; muscle; intestine; prostate; mixed; liver; pancreas; skin; bone marrow; trachea; bladder; thyroid; cervix; heart; kidney; ovary; bone; blood; stomach; adrenal gland; lymph node; connective tissue; spleen; mammary gland; ascites; pineal gland; pharynx; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21
UniSTS entry: Chr 18 A005R33 [Map Viewer]
UniSTS entry: Chr 18 G20447
UniSTS entry: Chr 18 WI-19692 [Map Viewer]
UniSTS entry: Chr 18 D18S942E
UniSTS entry: Chr 18 SHGC-57822
UniSTS entry: Chr 18 RH94118
UniSTS entry: Chr 18 A009I40 [Map Viewer]
UniSTS entry: Chr 18 G32567
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (31)

BC047353.1 Homo sapiens methyl-CpG binding domain protein 1, mRNA (cDNA clone IMAGE:4510451) PA
AJ564845.1 Homo sapiens mRNA for methyl-CpG binding domain protein 1, splice form 6 (MBD1 gene) P
NM_015844.2 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 3, mRNA PA
NM_015845.3 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 2, mRNA PA
NM_015846.3 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 1, mRNA PA
NM_015847.3 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 5, mRNA PA
NM_002384.2 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 4, mRNA PA
AF078830.1 Homo sapiens methyl-CpG binding protein splice variant 1 (MBD1) mRNA, complete cds P
AF078831.1 Homo sapiens methyl-CpG binding protein splice variant 2 (MBD1) mRNA, complete cds P
AF078832.1 Homo sapiens methyl-CpG binding protein splice variant 3 (MBD1) mRNA, complete cds P
AF078833.1 Homo sapiens methyl-CpG binding protein splice variant 4 (MBD1) mRNA, complete cds P
AB209765.1 Homo sapiens mRNA for methyl-CpG binding domain protein 1 isoform PCM1 variant protein P
AK225948.1 Homo sapiens mRNA for Splice isoform 6 of Q9UIS9 variant, clone: FCC115E03 PA
AK225889.1 Homo sapiens mRNA for methyl-CpG binding domain protein 1 isoform 1 variant, clone: FCC121D05 PA
EF488685.1 Homo sapiens methyl-CpG binding domain protein 1 variant 8 (MBD1) mRNA, complete cds, alternatively spliced P
AK291519.1 Homo sapiens cDNA FLJ75178 complete cds, highly similar to Homo sapiens methyl-CpG binding protein splice variant 1 (MBD1) mRNA P
BC033242.1 Homo sapiens methyl-CpG binding domain protein 1, mRNA (cDNA clone MGC:45928 IMAGE:5432943), complete cds PA
AK300759.1 Homo sapiens cDNA FLJ55386 complete cds, highly similar to Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 4, mRNA P
AK295401.1 Homo sapiens cDNA FLJ55972 complete cds, highly similar to Methyl-CpG-binding domain protein 1 P
AK302004.1 Homo sapiens cDNA FLJ60940 complete cds, highly similar to Methyl-CpG-binding domain protein 1 PA
AF072241.1 Homo sapiens methyl-CpG binding protein MBD1 (MBD1) mRNA, partial cds
NM_001204151.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 13, mRNA P
NM_001204143.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 12, mRNA PA
NM_001204142.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 11, mRNA PA
NM_001204141.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 10, mRNA PA
NM_001204140.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 9, mRNA PA
NM_001204139.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 14, mRNA PA
NM_001204138.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 8, mRNA PA
NM_001204137.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 7, mRNA PA
NM_001204136.1 Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 6, mRNA PA
Y10746.1 H.sapiens mRNA for protein containing MBD 1 P

EST sequences (10 of 594) [Show all sequences]

AA976837.1 Clone IMAGE:1588340 uncharacterized tissue 3' read A
AA984466.1 Clone IMAGE:1630070 brain 3' read P
AI004653.1 Clone IMAGE:1626069 mixed 3' read
T05798.1 Clone HFBDG56 brain
R19532.1 Clone IMAGE:33399 brain 5' read
AI052268.1 Clone IMAGE:1670052 brain 3' read
R21141.1 Clone IMAGE:36731 brain 5' read
BX097056.1 Clone IMAGp998C166077_;_IMAGE:2444103 uterus A
BX114301.1 Clone IMAGp998P02189_;_IMAGE:134257 placenta
AI205309.1 Clone IMAGE:1952943 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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