NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:136630     UniGene Hs.38449     Homo sapiens (human)   SERPINE2
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2)

Human protein-coding gene SERPINE2. Represented by 1231 ESTs from 282 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 136630 - Hs.38449]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001167141.2 PREDICTED: glia-derived nexin isoform 3 P. troglodytes 100.0 408
NP_001130002.1 SERPINE2 gene product H. sapiens 100.0 408
NP_033281.1 Serpine2 gene product M. musculus 88.9 396
NP_001086989.1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 precursor X. laevis 80.6 391
NP_956478.1 serpine2 gene product D. rerio 60.6 385
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_001109037.2 PREDICTED: glia-derived nexin isoform 3 M. mulatta 98.5 408
XP_003908059.1 PREDICTED: glia-derived nexin isoform 1 P. anubis 98.2 396

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; connective tissue; skin; testis; uncharacterized tissue; vascular; embryonic tissue; kidney; bone; lung; intestine; uterus; mixed; ear; esophagus; thyroid; heart; bone marrow; muscle; mammary gland; liver; ovary; prostate; spleen; thymus; eye; blood; epididymis; larynx; bladder; pancreas; mouth; adrenal gland; cervix; stomach; lymph node; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q36.1
UniSTS entry: Chr 2 D2S2574 [Map Viewer]
UniSTS entry: Chr 2 G31099
UniSTS entry: Chr 16 PMC18810P1
UniSTS entry: Chr 16 PMC350564P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC042628.1 Homo sapiens serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2, mRNA (cDNA clone MGC:42573 IMAGE:4824856), complete cds PA
AK225823.1 Homo sapiens mRNA for plasminogen activator inhibitor type 1, member 2 variant, clone: FCC128D03 PA
BC015663.2 Homo sapiens serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2, mRNA (cDNA clone MGC:23129 IMAGE:4578406), complete cds PA
AK312499.1 Homo sapiens cDNA, FLJ92861, highly similar to Homo sapiens serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2), mRNA P
AK297588.1 Homo sapiens cDNA FLJ51896 complete cds, highly similar to Glia-derived nexin precursor P
AK295564.1 Homo sapiens cDNA FLJ55211 complete cds, highly similar to Glia-derived nexin precursor P
NM_001136530.1 Homo sapiens serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2), transcript variant 4, mRNA PA
NM_001136528.1 Homo sapiens serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2), transcript variant 2, mRNA PA
M17783.1 Human glia-derived nexin (GDN) mRNA, 5' end P
NM_006216.3 Homo sapiens serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2), transcript variant 1, mRNA PA
NR_073116.1 Homo sapiens serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2), transcript variant 3, non-coding RNA PA

EST sequences (10 of 1231) [Show all sequences]

R14835.1 Clone IMAGE:30206 brain 5' read A
AI039889.1 Clone IMAGE:1664273 skin 3' read A
AI079435.1 Clone IMAGE:1680494 skin 3' read
AI129907.1 Clone IMAGE:1712159 uterus 3' read
AI151283.1 Clone IMAGE:1721283 uterus 3' read P
BX099798.1 Clone IMAGp998B191161_;_IMAGE:487986 uterus P
AI189318.1 Clone IMAGE:1722413 uterus 3' read
AI207392.1 Clone IMAGE:1759355 placenta 3' read P
CB155858.1 Clone B2N807043-12-B05 brain 5' read P
CB131588.1 Clone L13SNU387-9-F10 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help