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UGID:136588     UniGene Hs.38032     Homo sapiens (human)   ATG7
Autophagy related 7 (ATG7)

Human protein-coding gene ATG7. Represented by 494 ESTs from 237 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 136588 - Hs.38032]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006386.1 ATG7 gene product H. sapiens 100.0 702
NP_083111.1 Atg7 gene product M. musculus 96.3 696
XP_001703365.1 autophagy protein C. reinhardtii 55.9 387
NP_568652.1 ubiquitin-like modifier-activating enzyme atg7 A. thaliana 54.4 686
XP_960919.1 hypothetical protein NCU06672 N. crassa 53.7 449
NP_012041.1 Atg7p S. cerevisiae 53.3 368
NP_725809.1 Autophagy-specific gene 7, isoform B D. melanogaster 53.1 392
NP_502064.1 Protein ATG-7 C. elegans 51.7 360
Other hits (2 of 57) [Show all]SpeciesId(%)Len(aa)
XP_001088170.1 PREDICTED: autophagy-related protein 7 isoform 4 M. mulatta 99.4 702
XP_003894146.1 PREDICTED: ubiquitin-like modifier-activating enzyme ATG7 isoform 2 P. anubis 99.3 702

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; intestine; placenta; mixed; lung; skin; liver; mammary gland; embryonic tissue; bone marrow; mouth; thyroid; ovary; kidney; prostate; connective tissue; muscle; blood; cervix; parathyroid; spleen; thymus; trachea; eye; heart; uterus; stomach; pharynx; pancreas; adrenal gland; ear; umbilical cord; bladder; lymph node; ascites; vascular; salivary gland; bone
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p25.3
UniSTS entry: Chr 3 SHGC-76706 [Map Viewer]
UniSTS entry: Chr 3 RH25345
UniSTS entry: Chr 3 RH15949 [Map Viewer]
UniSTS entry: Chr 3 D3S3828
UniSTS entry: Chr 3 SHGC-76717 [Map Viewer]
UniSTS entry: Chr 3 RH98571
UniSTS entry: Chr 3 D3S3454
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF094516.1 Homo sapiens E1-like protein mRNA, complete cds PA
NM_006395.2 Homo sapiens autophagy related 7 (ATG7), transcript variant 1, mRNA PA
AL122075.1 Homo sapiens mRNA; cDNA DKFZp434N0735 (from clone DKFZp434N0735); partial cds PA
BC000091.2 Homo sapiens ATG7 autophagy related 7 homolog (S. cerevisiae), mRNA (cDNA clone MGC:1334 IMAGE:3504204), complete cds PA
AK314504.1 Homo sapiens cDNA, FLJ95321, highly similar to Homo sapiens ATG7 autophagy related 7 homolog (S. cerevisiae) (ATG7), mRNA P
AK298833.1 Homo sapiens cDNA FLJ53475 complete cds, highly similar to Autophagy-related protein 7 P
AK303694.1 Homo sapiens cDNA FLJ53485 complete cds, highly similar to Autophagy-related protein 7 P
NM_001136031.2 Homo sapiens autophagy related 7 (ATG7), transcript variant 2, mRNA PA
AK075221.1 Homo sapiens cDNA FLJ90740 fis, clone PLACE1011045, highly similar to Autophagy-related protein 7 P
BC014319.1 Homo sapiens, clone IMAGE:3685928, mRNA A
NM_001144912.1 Homo sapiens autophagy related 7 (ATG7), transcript variant 3, mRNA PA

EST sequences (10 of 494) [Show all sequences]

AA975772.1 Clone IMAGE:1589453 kidney 3' read
AA988107.1 Clone IMAGE:1604630 lung 3' read
AA988350.1 Clone IMAGE:1605549 kidney 3' read
AI005008.1 Clone IMAGE:1625575 mixed 3' read
AI032781.1 Clone IMAGE:1647068 parathyroid 3' read
AI080104.1 Clone IMAGE:1677387 mixed 3' read
AI183490.1 Clone IMAGE:1732141 heart 3' read
AI216553.1 Clone IMAGE:1883971 lung 3' read
AI217905.1 Clone IMAGE:1753325 testis 3' read A
CB161297.1 Clone L17N670205n1-20-H11 liver 5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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