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UGID:201413     UniGene Hs.376206     Homo sapiens (human)   KLF4
Kruppel-like factor 4 (gut) (KLF4)

Human protein-coding gene KLF4. Represented by 228 ESTs from 121 cDNA libraries. Corresponds to reference sequence NM_004235.4. [UniGene 201413 - Hs.376206]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001141754.1 PREDICTED: Krueppel-like factor 4 isoform 2 P. troglodytes 100.0 478
NP_004226.3 KLF4 gene product H. sapiens 100.0 478
NP_001136265.1 KLF4 gene product M. mulatta 99.8 478
XP_003911448.1 PREDICTED: Krueppel-like factor 4 isoform 1 P. anubis 99.8 478
NP_034767.2 Klf4 gene product M. musculus 93.8 482
NP_001080430.1 Kruppel-like factor 2 (lung) X. laevis 81.2 181
NP_611747.2 CG42741 D. melanogaster 75.2 100
NP_507995.2 Protein KLF-2 C. elegans 69.6 125
NP_001106955.1 klf4a gene product D. rerio 63.5 395
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
NP_001098855.1 KLF4 gene product B. taurus 96.9 476
NP_001157691.1 KLF4 gene product O. aries 96.7 476

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: spleen; uterus; connective tissue; placenta; testis; eye; mixed; brain; heart; prostate; mouth; intestine; mammary gland; thyroid; pancreas; lung; vascular; skin; larynx; uncharacterized tissue; adipose tissue; stomach; ear; liver; ascites; trachea; embryonic tissue; cervix; kidney; lymph node; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q31
UniSTS entry: Chr 9 Klf4
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_004235.4 Homo sapiens Kruppel-like factor 4 (gut) (KLF4), mRNA PA
AF105036.1 Homo sapiens zinc finger transcription factor GKLF mRNA, complete cds P
AK313489.1 Homo sapiens cDNA, FLJ94042, highly similar to Homo sapiens Kruppel-like factor 4 (gut) (KLF4), mRNA P
BC029923.1 Homo sapiens Kruppel-like factor 4 (gut), mRNA (cDNA clone MGC:34918 IMAGE:5111134), complete cds PA
BC030811.1 Homo sapiens Kruppel-like factor 4 (gut), mRNA (cDNA clone MGC:22411 IMAGE:4703002), complete cds PA
HM026463.1 Homo sapiens Kruppel-like factor 4 short isoform (KLF4) mRNA, complete cds, alternatively spliced P
U70663.1 Human zinc finger transcription factor hEZF (EZF) mRNA, complete cds P
HF546202.1 Homo sapiens mRNA for Kruppel-like factor 4 (gut), splice variant 2 (KLF4 gene)
HF546213.1 Homo sapiens mRNA for Kruppel-like factor 4 (gut), splice variant 1b (KLF4 gene)
HF546201.1 Homo sapiens mRNA for Kruppel-like factor 4 (gut), splice variant 1a (KLF4 gene)
AF022184.1 Homo sapiens Kruppel-like zinc finger protein (EZF) mRNA, complete cds P

EST sequences (10 of 228) [Show all sequences]

AA904960.1 Clone IMAGE:1504705 mixed 3' read
AI014784.1 Clone IMAGE:1623022 embryonic tissue 3' read A
AI024576.1 Clone IMAGE:1642445 testis 3' read A
AI127241.1 Clone IMAGE:1708571 heart 3' read A
CB067315.1 Clone IMAGE: pancreas 3' read A
CB067619.1 Clone IMAGE: pancreas 5' read
BX090290.1 Clone IMAGp998N12235_;_IMAGE:151883 placenta
AI266211.1 Clone IMAGE:1932344 mixed 3' read A
AI290876.1 Clone IMAGE:1881771 lung 3' read
AI338031.1 Clone IMAGE:1950000 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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