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UGID:201298     UniGene Hs.375836     Homo sapiens (human)   KSR2
Kinase suppressor of ras 2 (KSR2)

Human protein-coding gene KSR2. Represented by 48 ESTs from 26 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_173598.4. [UniGene 201298 - Hs.375836]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001145739.3 PREDICTED: kinase suppressor of Ras 2 isoform 1 P. troglodytes 100.0 937
NP_775869.3 KSR2 gene product H. sapiens 100.0 920
XP_003907272.1 PREDICTED: LOW QUALITY PROTEIN: kinase suppressor of Ras 2 P. anubis 99.8 937
XP_001083311.2 PREDICTED: kinase suppressor of Ras 2 M. mulatta 99.6 900
NP_001108017.2 Ksr2 gene product M. musculus 95.8 948
NP_001137513.1 kinase suppressor of Ras 2 D. rerio 84.7 926
NP_524236.2 kinase suppressor of ras D. melanogaster 50.3 300
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
NP_001193791.1 kinase suppressor of Ras 2 B. taurus 98.8 937
XP_003132939.3 PREDICTED: kinase suppressor of Ras 2, partial S. scrofa 98.7 790

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; muscle; mixed; uncharacterized tissue; lymph node; pancreas; pituitary gland; kidney; eye
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24.22-q24.23
UniSTS entry: Chr 12 D12S1780 [Map Viewer]
UniSTS entry: Chr 12 D12S1246E
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_173598.4 Homo sapiens kinase suppressor of ras 2 (KSR2), mRNA P
AY345972.1 Homo sapiens kinase suppressor of Ras-2 (KSR2) mRNA, complete cds P
BX648958.1 Homo sapiens mRNA; cDNA DKFZp686L0948 (from clone DKFZp686L0948) A
AF403225.1 Homo sapiens Shinc-4 mRNA, partial sequence
BC107106.1 Homo sapiens kinase suppressor of ras 2, mRNA (cDNA clone IMAGE:40019270), partial cds P
BC107107.1 Homo sapiens kinase suppressor of ras 2, mRNA (cDNA clone IMAGE:40019271), partial cds P
BC127603.1 Homo sapiens kinase suppressor of ras 2, mRNA (cDNA clone MGC:141700 IMAGE:40019272), complete cds P
AK098831.1 Homo sapiens cDNA FLJ25965 fis, clone TST04647 P

EST sequences (10 of 48) [Show all sequences]

R24848.1 Clone IMAGE:34114 brain 5' read
BX106702.1 Clone IMAGp998B16157_;_IMAGE:34114 brain A
AI292005.1 Clone IMAGE:1895787 lung 3' read
AI298955.1 Clone IMAGE:1896957 lung 3' read A
AI692426.1 Clone IMAGE:2336848 lung 3' read A
AI763301.1 Clone IMAGE:2385466 kidney 3' read
AI832042.1 Clone IMAGE:2410969 lymph node 3' read A
Z43303.1 Clone c-18f12 brain
F02737.1 Clone c-18f12 brain 3' read A
BX475247.1 Clone DKFZp686P19175 muscle 5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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