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UGID:201298     UniGene Hs.375836     Homo sapiens (human)   KSR2
Kinase suppressor of ras 2 (KSR2)

Human protein-coding gene KSR2. Represented by 48 ESTs from 26 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_173598.4. [UniGene 201298 - Hs.375836]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001145739.3 PREDICTED: kinase suppressor of Ras 2 isoform 1 P. troglodytes 100.0 937
NP_775869.3 KSR2 gene product H. sapiens 100.0 920
XP_003907272.1 PREDICTED: LOW QUALITY PROTEIN: kinase suppressor of Ras 2 P. anubis 99.8 937
XP_001083311.2 PREDICTED: kinase suppressor of Ras 2 M. mulatta 99.6 900
NP_001108017.2 Ksr2 gene product M. musculus 95.8 948
NP_001137513.1 kinase suppressor of Ras 2 D. rerio 84.7 926
NP_524236.2 kinase suppressor of ras D. melanogaster 50.3 300
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
NP_001193791.1 kinase suppressor of Ras 2 B. taurus 98.8 937
XP_003132939.3 PREDICTED: kinase suppressor of Ras 2, partial S. scrofa 98.7 790

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; muscle; mixed; uncharacterized tissue; lymph node; pancreas; pituitary gland; kidney; eye
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24.22-q24.23
UniSTS entry: Chr 12 D12S1780 [Map Viewer]
UniSTS entry: Chr 12 D12S1246E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_173598.4 Homo sapiens kinase suppressor of ras 2 (KSR2), mRNA P
AY345972.1 Homo sapiens kinase suppressor of Ras-2 (KSR2) mRNA, complete cds P
BX648958.1 Homo sapiens mRNA; cDNA DKFZp686L0948 (from clone DKFZp686L0948) A
AF403225.1 Homo sapiens Shinc-4 mRNA, partial sequence
BC107106.1 Homo sapiens kinase suppressor of ras 2, mRNA (cDNA clone IMAGE:40019270), partial cds P
BC107107.1 Homo sapiens kinase suppressor of ras 2, mRNA (cDNA clone IMAGE:40019271), partial cds P
BC127603.1 Homo sapiens kinase suppressor of ras 2, mRNA (cDNA clone MGC:141700 IMAGE:40019272), complete cds P
AK098831.1 Homo sapiens cDNA FLJ25965 fis, clone TST04647 P

EST sequences (10 of 48) [Show all sequences]

R24848.1 Clone IMAGE:34114 brain 5' read
BX106702.1 Clone IMAGp998B16157_;_IMAGE:34114 brain A
AI292005.1 Clone IMAGE:1895787 lung 3' read
AI298955.1 Clone IMAGE:1896957 lung 3' read A
AI692426.1 Clone IMAGE:2336848 lung 3' read A
AI763301.1 Clone IMAGE:2385466 kidney 3' read
AI832042.1 Clone IMAGE:2410969 lymph node 3' read A
Z43303.1 Clone c-18f12 brain
F02737.1 Clone c-18f12 brain 3' read A
BX475247.1 Clone DKFZp686P19175 muscle 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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