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UGID:200061     UniGene Hs.372840     Homo sapiens (human)   APBB1
Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1)

Human protein-coding gene APBB1. Represented by 542 ESTs from 191 cDNA libraries. Corresponds to 11 reference sequences (different isoforms). [UniGene 200061 - Hs.372840]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001155.1 APBB1 gene product H. sapiens 100.0 709
XP_003312937.1 PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform 1 P. troglodytes 100.0 707
XP_002799719.1 PREDICTED: amyloid beta A4 precursor protein-binding family B member 1-like isoform 3 M. mulatta 100.0 486
XP_003910345.1 PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform 1 P. anubis 99.6 708
NP_001240814.1 Apbb1 gene product M. musculus 97.2 709
NP_001087003.1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) X. laevis 68.7 600
XP_693392.5 PREDICTED: amyloid beta A4 precursor protein-binding family B member 2-like D. rerio 63.4 562
Other hits (2 of 26) [Show all]SpeciesId(%)Len(aa)
NP_001068654.1 APBB1 gene product B. taurus 98.7 706
XP_534037.4 PREDICTED: LOW QUALITY PROTEIN: amyloid beta A4 precursor protein-binding family B member 1 C. lupus familiaris 98.6 709

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; eye; uncharacterized tissue; pancreas; mixed; uterus; skin; muscle; embryonic tissue; vascular; lung; prostate; blood; kidney; ovary; adrenal gland; mammary gland; thymus; stomach; liver; ascites; connective tissue; thyroid; lymph; nerve; bone; pituitary gland; lymph node; bone marrow; heart; salivary gland; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15
UniSTS entry: Chr 11 A002D29
UniSTS entry: RH125131
UniSTS entry: Apbb1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (42)

BX538185.1 Homo sapiens mRNA; cDNA DKFZp686G05200 (from clone DKFZp686G05200) PA
NM_001164.3 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 1, mRNA PA
EF103274.2 Homo sapiens amyloid beta A4 precursor protein-binding family B member 1 transcript variant 3 (APBB1) mRNA, complete cds, alternatively spliced PA
BC010854.2 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65), mRNA (cDNA clone MGC:9072 IMAGE:3905603), complete cds PA
AK311725.1 Homo sapiens cDNA, FLJ18767 P
AK309000.1 Homo sapiens cDNA, FLJ99041 P
AK308782.1 Homo sapiens cDNA, FLJ98823 P
AK311413.1 Homo sapiens cDNA, FLJ18455 P
AK308559.1 Homo sapiens cDNA, FLJ98600 P
AK311149.1 Homo sapiens cDNA, FLJ18191 P
AK311141.1 Homo sapiens cDNA, FLJ18183 P
AK311101.1 Homo sapiens cDNA, FLJ18143 P
AK311091.1 Homo sapiens cDNA, FLJ18133 P
AK309445.1 Homo sapiens cDNA, FLJ99486 P
AK309434.1 Homo sapiens cDNA, FLJ99475 P
AK098207.1 Homo sapiens cDNA FLJ40888 fis, clone UTERU2000844 P
NM_145689.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 2, mRNA PA
AF394214.1 Homo sapiens adaptor protein FE65a2 (APBB1) mRNA, APBB1-2 allele, partial cds; alternatively spliced PA
AK315965.1 Homo sapiens cDNA, FLJ78864 complete cds, highly similar to Amyloid beta A4 precursor protein-bindingfamily B member 1 PA
AK297550.1 Homo sapiens cDNA FLJ57330 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK297544.1 Homo sapiens cDNA FLJ58369 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK297542.1 Homo sapiens cDNA FLJ57329 complete cds, moderately similar to Amyloid beta A4 precursor protein-binding family B member 1
AK295837.1 Homo sapiens cDNA FLJ50968 complete cds, highly similar to Amyloid beta A4 precursor protein-bindingfamily B member 1 P
AK295425.1 Homo sapiens cDNA FLJ51859 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK295241.1 Homo sapiens cDNA FLJ57305 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK294495.1 Homo sapiens cDNA FLJ52204 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK293711.1 Homo sapiens cDNA FLJ53875 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK293643.1 Homo sapiens cDNA FLJ53829 complete cds, highly similar to Amyloid beta A4 precursor protein-bindingfamily B member 1 P
AK293613.1 Homo sapiens cDNA FLJ52221 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK293554.1 Homo sapiens cDNA FLJ54642 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK293550.1 Homo sapiens cDNA FLJ61679 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 P
AK293452.1 Homo sapiens cDNA FLJ53874 complete cds, highly similar to Amyloid beta A4 precursor protein-binding family B member 1 PA
NM_001257326.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 5, mRNA PA
NM_001257324.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 3, mRNA P
NM_001257322.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 10, mRNA P
NM_001257320.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 6, mRNA PA
NM_001257325.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 7, mRNA PA
NM_001257323.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 8, mRNA PA
NM_001257321.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 4, mRNA PA
NM_001257319.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 9, mRNA PA
NR_047512.1 Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 11, non-coding RNA PA
L77864.1 Homo sapiens stat-like protein (Fe65) mRNA, complete cds PA

EST sequences (10 of 542) [Show all sequences]

AA962581.1 Clone IMAGE:1597780 uncharacterized tissue 3' read A
AA970230.1 Clone IMAGE:1581362 mixed 3' read A
AI017891.1 Clone IMAGE:1628301 mixed 3' read A
AI033962.1 Clone IMAGE:1655866 mixed 3' read A
AI042602.1 Clone IMAGE:1665845 skin 3' read A
AI088830.1 Clone IMAGE:1686145 brain 3' read A
AI086807.1 Clone IMAGE:1679462 skin 3' read A
BX097347.1 Clone IMAGp998I15342_;_IMAGE:184022 brain P
AI218251.1 Clone IMAGE:1845507 mixed 3' read A
AI270653.1 Clone IMAGE:1979324 stomach 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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