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UGID:199182     UniGene Hs.371282     Homo sapiens (human)   TCF3
Transcription factor 3 (TCF3)

Human protein-coding gene TCF3. Represented by 649 ESTs from 215 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 199182 - Hs.371282]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003191.1 TCF3 gene product H. sapiens 100.0 653
NP_001157619.1 Tcf3 gene product M. musculus 87.3 651
NP_001079668.1 transcription factor E2-alpha X. laevis 72.6 657
NP_523376.1 ribosomal protein S19a, isoform A D. melanogaster 65.9 138
NP_001166154.1 zgc:113045 gene product D. rerio 64.4 651
NP_200925.1 40S ribosomal protein S19-3 A. thaliana 58.3 139
XP_962947.1 40S ribosomal protein S19 N. crassa 54.5 143
NP_492555.1 Protein RPS-19 C. elegans 53.6 140
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_003954574.1 PREDICTED: LOW QUALITY PROTEIN: transcription factor E2-alpha P. troglodytes 99.3 562
XP_003914643.1 PREDICTED: transcription factor E2-alpha P. anubis 98.6 650

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lymph node; uncharacterized tissue; brain; testis; lung; embryonic tissue; intestine; mixed; ovary; eye; uterus; mammary gland; lymph; tonsil; skin; adipose tissue; prostate; ascites; placenta; liver; pancreas; bladder; muscle; ear; kidney; cervix; blood; stomach; bone; heart; spleen; thymus; pharynx; mouth; connective tissue; bone marrow; parathyroid; salivary gland; adrenal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
UniSTS entry: Chr 19 RH12886
UniSTS entry: Chr 19 WI-18183 [Map Viewer]
UniSTS entry: Chr 19 STS-M65214
UniSTS entry: Chr 19 G15946
UniSTS entry: Chr 19 G29322
UniSTS entry: Chr 19 TCF3_4169
UniSTS entry: Chr 1 RH79941
UniSTS entry: Chr 1 MARC_24185-24186:1034710364:1
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

NM_003200.3 Homo sapiens transcription factor 3 (TCF3), transcript variant 1, mRNA PA
AY311345.1 Homo sapiens E2A/PBX1 fusion protein (E2A/PBX1 fusion) mRNA, partial cds; alternatively spliced
AL117663.1 Homo sapiens mRNA; cDNA DKFZp586L1824 (from clone DKFZp586L1824) A
M31222.1 Human e12 protein (E2A) mRNA, complete cds P
M65214.1 Human (HeLa) helix-loop-helix protein HE47 (E2A) mRNA, 3' end P
M24405.1 Homo sapiens (clone E12) kappa-E2-binding factor mRNA, 3' end P
BC110580.1 Homo sapiens transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), mRNA (cDNA clone MGC:129648 IMAGE:40007779), complete cds P
M31523.1 Human transcription factor (E2A) mRNA, complete cds P
BC005166.2 Homo sapiens transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), mRNA (cDNA clone IMAGE:3534334), partial cds A
BC009346.1 Homo sapiens cDNA clone IMAGE:4131112, **** WARNING: chimeric clone **** PA
BC011665.2 Homo sapiens transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), mRNA (cDNA clone IMAGE:4110737), partial cds PA
EU155120.1 Homo sapiens p120-E2A fusion (NOL1-TCF3 fusion) mRNA, partial sequence
BC014680.1 Homo sapiens transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), mRNA (cDNA clone IMAGE:3864558), with apparent retained intron A
NM_001136139.2 Homo sapiens transcription factor 3 (TCF3), transcript variant 2, mRNA PA
AK024806.1 Homo sapiens cDNA: FLJ21153 fis, clone CAS09631, highly similar to HUMTFAA Human transcription factor (E2A) mRNA A
M24404.1 Homo sapiens (clone E47) kappa-E2-binding factor mRNA, partial cds P
X52078.1 Human transcription factor (ITF-1) mRNA, 3' end P

EST sequences (10 of 649) [Show all sequences]

AA969858.1 Clone IMAGE:1579438 mixed 3' read A
AA971677.1 Clone IMAGE:1583637 mixed 3' read A
AA971973.1 Clone IMAGE:1582746 mixed 3' read
AA977695.1 Clone IMAGE:1558385 lung 3' read
R15325.1 Clone IMAGE:29796 brain 5' read
AA992325.1 Clone IMAGE:1620515 testis 3' read P
AA906873.1 Clone IMAGE:1524021 mixed 3' read P
AI018497.1 Clone IMAGE:1630934 mammary gland 3' read PA
AI023158.1 Clone IMAGE:1651757 skin 3' read P
AI027246.1 Clone IMAGE:1644463 testis 3' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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