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UGID:198092     UniGene Hs.369448     Homo sapiens (human)   FRAS1
Fraser syndrome 1 (FRAS1)

Human protein-coding gene FRAS1. Represented by 160 ESTs from 91 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 198092 - Hs.369448]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_079350.5 FRAS1 gene product H. sapiens 100.0 4011
NP_780682.3 Fras1 gene product M. musculus 89.3 4009
NP_001124312.1 extracellular matrix protein FRAS1 D. rerio 71.9 3933
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_517202.2 PREDICTED: extracellular matrix protein FRAS1 P. troglodytes 99.4 4011
XP_003898773.1 PREDICTED: extracellular matrix protein FRAS1 P. anubis 95.9 3838

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; embryonic tissue; mixed; uncharacterized tissue; placenta; intestine; testis; muscle; ovary; vascular; stomach; eye; kidney; mammary gland; mouth; thyroid; uterus; heart; liver; pituitary gland; connective tissue; bone; adrenal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q21.21
UniSTS entry: Chr 4 SHGC-16556
UniSTS entry: Chr 4 RH15875 [Map Viewer]
UniSTS entry: Chr 4 SHGC4-1840
UniSTS entry: Chr 4 D4S2602E
UniSTS entry: Chr 4 SGC32653 [Map Viewer]
UniSTS entry: Chr 4 SHGC-60067
UniSTS entry: Chr 4 G34409
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

BC052281.1 Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:3926947), partial cds PA
BX647949.1 Homo sapiens mRNA; cDNA DKFZp686E1251 (from clone DKFZp686E1251) PA
BX647420.1 Homo sapiens mRNA; cDNA DKFZp686P08111 (from clone DKFZp686P08111) PA
BC064487.1 Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:3834928), partial cds PA
AL157471.1 Homo sapiens mRNA; cDNA DKFZp761P1423 (from clone DKFZp761P1423) PA
CR627393.1 Homo sapiens mRNA; cDNA DKFZp686I05113 (from clone DKFZp686I05113) PA
AB040933.2 Homo sapiens mRNA for KIAA1500 protein, partial cds P
BC094853.1 Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:5020583) PA
AK025684.1 Homo sapiens cDNA: FLJ22031 fis, clone HEP08734 PA
NM_025074.6 Homo sapiens Fraser syndrome 1 (FRAS1), transcript variant 1, mRNA PA
AK027833.1 Homo sapiens cDNA FLJ14927 fis, clone PLACE1009094, weakly similar to FURIN-LIKE PROTEASE 2 PRECURSOR (EC P
BC131821.1 Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:40126801), complete cds P
BC131820.1 Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:40126796), complete cds P
AK096838.1 Homo sapiens cDNA FLJ39519 fis, clone PUAEN2001260
AK092082.1 Homo sapiens cDNA FLJ34763 fis, clone NT2NE2002186 P
AL833581.1 Homo sapiens mRNA; cDNA DKFZp686M0356 (from clone DKFZp686M0356) PA
AL831853.1 Homo sapiens mRNA; cDNA DKFZp761C1517 (from clone DKFZp761C1517) PA
BC020192.1 Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:4111654), partial cds PA
BC009254.2 Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:3028776), partial cds PA
NM_001166133.1 Homo sapiens Fraser syndrome 1 (FRAS1), transcript variant 2, mRNA PA

EST sequences (10 of 160) [Show all sequences]

R14543.1 Clone IMAGE:29217 brain 5' read
R16418.1 Clone IMAGE:129320 mixed 5' read
AI001790.1 Clone IMAGE:1619377 testis 3' read A
R19232.1 Clone IMAGE:33027 brain 5' read
AA928909.1 Clone IMAGE:1568287 lung 3' read
R19840.1 Clone IMAGE:33837 brain 5' read
AI300987.1 Clone IMAGE:1908385 lung 3' read A
AI358195.1 Clone IMAGE:1989454 uterus 3' read A
R46219.1 Clone IMAGE:152498 mammary gland 3' read
R45939.1 Clone IMAGE:33837 brain 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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