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UGID:197027     UniGene Hs.365706     Homo sapiens (human)   MGP
Matrix Gla protein (MGP)

Human protein-coding gene MGP. Represented by 745 ESTs from 212 cDNA libraries. EST representation biased toward neonate. Corresponds to 2 reference sequences (different isoforms). [UniGene 197027 - Hs.365706]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001177768.1 MGP gene product H. sapiens 100.0 127
NP_032623.1 Mgp gene product M. musculus 85.4 103
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_003313567.1 PREDICTED: uncharacterized protein LOC465310 isoform 3 P. troglodytes 98.4 127
XP_001090877.1 PREDICTED: matrix Gla protein M. mulatta 97.1 102

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: vascular; brain; eye; mixed; connective tissue; mammary gland; prostate; pancreas; heart; uterus; kidney; esophagus; pharynx; liver; blood; cervix; stomach; umbilical cord; uncharacterized tissue; muscle; lung; larynx; intestine; ear; lymph node; testis; pituitary gland; thyroid; mouth; adrenal gland; placenta; ovary; skin; adipose tissue; bone; thymus; embryonic tissue; salivary gland; amniotic fluid; nerve; tonsil; pineal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p12.3
UniSTS entry: Chr 12 G44728
UniSTS entry: Chr 12 STS-X53331
UniSTS entry: Chr 12 D12S1925 [Map Viewer]
UniSTS entry: Chr 12 SHGC-12684
UniSTS entry: Chr 12 RH93429
UniSTS entry: Chr 1 D10S16
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BT006733.1 Homo sapiens matrix Gla protein mRNA, complete cds P
NM_000900.3 Homo sapiens matrix Gla protein (MGP), transcript variant 2, mRNA P
CR450358.1 Homo sapiens full open reading frame cDNA clone RZPDo834C013D for gene MGP, matrix Gla protein; complete cds; without stopcodon P
BC070314.1 Homo sapiens matrix Gla protein, mRNA (cDNA clone MGC:88316 IMAGE:6653229), complete cds PA
BC093078.1 Homo sapiens matrix Gla protein, mRNA (cDNA clone MGC:111227 IMAGE:30405585), complete cds PA
X07362.1 Human mRNA for matrix Gla protein (MGP) P
M58549.1 Human matrix Gla protein (MGP) mRNA, complete cds P
AY542304.1 Homo sapiens GIG36 mRNA, complete cds P
BC005272.1 Homo sapiens matrix Gla protein, mRNA (cDNA clone MGC:12316 IMAGE:3930143), complete cds PA
AK312029.1 Homo sapiens cDNA, FLJ92305, Homo sapiens matrix Gla protein (MGP), mRNA P
AK310040.1 Homo sapiens cDNA, FLJ17082
X53331.1 Human mRNA for matrix Gla protein P
NM_001190839.1 Homo sapiens matrix Gla protein (MGP), transcript variant 1, mRNA P

EST sequences (10 of 745) [Show all sequences]

AA836844.1 Clone IMAGE:1422694 kidney P
AA864282.1 Clone IMAGE:1460231 kidney 3' read P
AA962019.1 Clone IMAGE:1593844 kidney 3' read
AA968571.1 Clone IMAGE:1592185 kidney 3' read
AA969697.1 Clone IMAGE:1574725 kidney 3' read A
AA971294.1 Clone IMAGE:1574931 kidney 3' read PA
AA975721.1 Clone IMAGE:1591088 kidney 3' read A
AA983329.1 Clone IMAGE:1590954 kidney 3' read A
AA985478.1 Clone IMAGE:1594203 kidney 3' read A
AA985555.1 Clone IMAGE:1601184 lung 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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