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UGID:195570     UniGene Hs.356697     Homo sapiens (human)   COX18
Cytochrome c oxidase assembly homolog 18 (yeast) (COX18)

Human protein-coding gene COX18. Represented by 142 ESTs from 73 cDNA libraries. Corresponds to reference sequence NM_173827.2. [UniGene 195570 - Hs.356697]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_517237.2 PREDICTED: mitochondrial inner membrane protein COX18 isoform 2 P. troglodytes 100.0 332
NP_776188.1 COX18 gene product H. sapiens 100.0 332
NP_001156928.1 mitochondrial inner membrane protein COX18 isoform 1 M. musculus 81.6 331
NP_001107941.1 zgc:174864 gene product D. rerio 62.2 286
NP_001090111.1 cytochrome c oxidase assembly homolog 18 X. laevis 62.0 320
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_003898830.1 PREDICTED: mitochondrial inner membrane protein COX18-like P. anubis 94.9 333
XP_001104459.2 PREDICTED: mitochondrial inner membrane protein COX18-like M. mulatta 94.6 333

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; testis; salivary gland; brain; intestine; blood; ovary; uterus; pancreas; bladder; mixed; placenta; prostate; lung; embryonic tissue; stomach; uncharacterized tissue; kidney; mouth; heart; eye; vascular; bone; nerve; ganglia; pineal gland; parathyroid; skin
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q13.3
UniSTS entry: Chr 1 D7S3207
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 4 STS-R43034 [Map Viewer]
UniSTS entry: Chr 1 GDB:631802
UniSTS entry: Chr 1 L17971
UniSTS entry: Chr 1 D8S2279
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_173827.2 Homo sapiens cytochrome c oxidase assembly homolog 18 (yeast) (COX18), nuclear gene encoding mitochondrial protein, mRNA P
BC071812.1 Homo sapiens COX18 cytochrome c oxidase assembly homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:6452620), partial cds PA
BC101684.1 Homo sapiens COX18 cytochrome c oxidase assembly homolog (S. cerevisiae), mRNA (cDNA clone MGC:126733 IMAGE:8069190), complete cds P
AM055752.1 Homo sapiens partial mRNA for Cox18Hs3 protein (COX18HS gene) P
AM055751.1 Homo sapiens partial mRNA for Cox18Hs2 protein (COX18HS gene) P
AM055750.1 Homo sapiens partial mRNA for Cox18Hs1 protein (COX18HS gene) P
AK096310.2 Homo sapiens cDNA FLJ38991 fis, clone NT2RI2008622 P
AK092641.1 Homo sapiens cDNA FLJ35322 fis, clone PROST2012157
BC143642.1 Homo sapiens COX18 cytochrome c oxidase assembly homolog (S. cerevisiae), mRNA (cDNA clone MGC:177173 IMAGE:9052156), complete cds P

EST sequences (10 of 142) [Show all sequences]

AA886866.1 Clone IMAGE:1493244 kidney 3' read A
AA973129.1 Clone IMAGE:1579821 mixed 3' read
R17830.1 Clone IMAGE:31673 brain 5' read
AI024757.1 Clone IMAGE:1643289 testis 3' read A
AI042199.1 Clone IMAGE:1660748 mixed 3' read A
BX116684.1 Clone IMAGp998I05113_;_IMAGE:121420 mixed
AI208464.1 Clone IMAGE:1837274 testis 3' read A
AI215593.1 Clone IMAGE:1845001 mixed 3' read P
AI302410.1 Clone IMAGE:1901750 kidney 3' read A
AI304708.1 Clone IMAGE:1913340 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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