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UGID:194530     UniGene Hs.352611     Homo sapiens (human)   NLRP6
NLR family, pyrin domain containing 6 (NLRP6)

Human protein-coding gene NLRP6. Represented by 18 ESTs from 8 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 194530 - Hs.352611]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_612202.1 NLRP6 gene product H. sapiens 100.0 891
NP_001074858.1 Nlrp6 gene product M. musculus 76.6 880
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_003909353.1 PREDICTED: NACHT, LRR and PYD domains-containing protein 6 P. anubis 96.2 892
XP_521701.3 PREDICTED: NACHT, LRR and PYD domains-containing protein 6 P. troglodytes 96.1 880

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; intestine; kidney; blood; testis; eye; thymus; trachea
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AY154461.1 Homo sapiens NALP6 (NALP6) mRNA, complete cds P
AK292668.1 Homo sapiens cDNA FLJ77198 complete cds, highly similar to Homo sapiens NACHT, leucine rich repeat and PYD containing 6 (NALP6), mRNA P
AF479748.1 Homo sapiens PYRIN-containing APAF1-like protein 5 mRNA, complete cds P
NM_138329.2 Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 1, mRNA P
NM_001276700.1 Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA

EST sequences (10 of 18) [Show all sequences]

AI344276.1 Clone IMAGE:2062740 intestine 3' read P
CD677002.1 Clone ho09h08 eye 5' read
CD636366.1 uncharacterized tissue P
CD636367.1 uncharacterized tissue P
CD636368.1 uncharacterized tissue P
CD636369.1 uncharacterized tissue P
CD636370.1 uncharacterized tissue P
CD636371.1 uncharacterized tissue P
CD636372.1 uncharacterized tissue P
CD636373.1 uncharacterized tissue P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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