NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:194530     UniGene Hs.352611     Homo sapiens (human)   NLRP6
NLR family, pyrin domain containing 6 (NLRP6)

Human protein-coding gene NLRP6. Represented by 18 ESTs from 8 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 194530 - Hs.352611]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_612202.1 NLRP6 gene product H. sapiens 100.0 891
NP_001074858.1 Nlrp6 gene product M. musculus 76.6 880
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_003909353.1 PREDICTED: NACHT, LRR and PYD domains-containing protein 6 P. anubis 96.2 892
XP_521701.3 PREDICTED: NACHT, LRR and PYD domains-containing protein 6 P. troglodytes 96.1 880

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; intestine; kidney; blood; testis; eye; thymus; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AY154461.1 Homo sapiens NALP6 (NALP6) mRNA, complete cds P
AK292668.1 Homo sapiens cDNA FLJ77198 complete cds, highly similar to Homo sapiens NACHT, leucine rich repeat and PYD containing 6 (NALP6), mRNA P
AF479748.1 Homo sapiens PYRIN-containing APAF1-like protein 5 mRNA, complete cds P
NM_138329.2 Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 1, mRNA P
NM_001276700.1 Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 2, mRNA

EST sequences (10 of 18) [Show all sequences]

AI344276.1 Clone IMAGE:2062740 intestine 3' read P
CD677002.1 Clone ho09h08 eye 5' read
CD636366.1 uncharacterized tissue P
CD636367.1 uncharacterized tissue P
CD636368.1 uncharacterized tissue P
CD636369.1 uncharacterized tissue P
CD636370.1 uncharacterized tissue P
CD636371.1 uncharacterized tissue P
CD636372.1 uncharacterized tissue P
CD636373.1 uncharacterized tissue P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help