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UGID:193709     UniGene Hs.349283     Homo sapiens (human)   CBX5
Chromobox homolog 5 (CBX5)

Human protein-coding gene CBX5. Represented by 965 ESTs from 372 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 193709 - Hs.349283]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001091785.2 PREDICTED: chromobox protein homolog 5-like isoform 1 M. mulatta 100.0 190
XP_003906542.1 PREDICTED: chromobox protein homolog 5 P. anubis 100.0 190
XP_522411.2 PREDICTED: chromobox protein homolog 5 isoform 2 P. troglodytes 100.0 190
NP_001120793.1 CBX5 gene product H. sapiens 100.0 190
XP_534787.3 PREDICTED: chromobox protein homolog 5 isoform 3 C. lupus familiaris 100.0 190
XP_001504610.1 PREDICTED: chromobox protein homolog 5-like isoform 2 E. caballus 100.0 190
XP_003126249.1 PREDICTED: chromobox protein homolog 5-like isoform 2 S. scrofa 100.0 190
NP_001180142.1 CBX5 gene product B. taurus 100.0 190
XP_002711080.1 PREDICTED: heterochromatin protein 1-alpha O. cuniculus 100.0 190
NP_001159662.1 CBX5 gene product O. aries 100.0 189
NP_001070257.1 chromobox protein homolog 5 M. musculus 99.0 190
NP_001080863.1 chromobox homolog 5 X. laevis 86.8 188
NP_001073653.1 cbx5 gene product D. rerio 70.8 202
NP_572521.2 heterochromatin protein 1b, isoform A D. melanogaster 52.6 175
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
NP_001100267.1 Cbx5 gene product R. norvegicus 99.0 190
XP_003216720.1 PREDICTED: chromobox protein homolog 5-like isoform 3 A. carolinensis 95.8 188

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; mixed; testis; uncharacterized tissue; eye; liver; lymph node; mammary gland; uterus; intestine; kidney; pancreas; lung; connective tissue; tonsil; bone marrow; bladder; blood; spinal cord; muscle; bone; amniotic fluid; ovary; pituitary gland; stomach; trachea; lymph; heart; prostate; thymus; placenta; pharynx; thyroid; skin; larynx; mouth; spleen; ascites; ganglia; salivary gland; cervix; parathyroid; nerve; esophagus; vascular; adrenal gland; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13.13
UniSTS entry: Chr 12 RH68193
UniSTS entry: Chr 12 D12S110E
UniSTS entry: Chr 12 WI-12071 [Map Viewer]
UniSTS entry: Chr 12 D12S1966 [Map Viewer]
UniSTS entry: Chr 12 RH64861
UniSTS entry: Chr 12 WI-15869 [Map Viewer]
UniSTS entry: Chr 12 RH102227
UniSTS entry: Chr 12 SGC34021 [Map Viewer]
UniSTS entry: Chr 1 D10S275
UniSTS entry: Chr 1 PMC156606P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BC047432.1 Homo sapiens cDNA clone IMAGE:5288883 A
NM_012117.2 Homo sapiens chromobox homolog 5 (CBX5), transcript variant 3, mRNA PA
CR457418.1 Homo sapiens full open reading frame cDNA clone RZPDo834G1110D for gene CBX5, chromobox homolog 5 (HP1 alpha homolog, Drosophila); complete cds, incl. stopcodon P
AK023520.1 Homo sapiens cDNA FLJ13458 fis, clone PLACE1003361
BC006821.1 Homo sapiens chromobox homolog 5 (HP1 alpha homolog, Drosophila), mRNA (cDNA clone MGC:4985 IMAGE:3448801), complete cds PA
AK056315.1 Homo sapiens cDNA FLJ31753 fis, clone NT2RI2007468
AK055641.1 Homo sapiens cDNA FLJ31079 fis, clone HSYRA2001595 A
AK313506.1 Homo sapiens cDNA, FLJ94062, Homo sapiens chromobox homolog 5 (HP1 alpha homolog, Drosophila)(CBX5), mRNA P
NM_001127322.1 Homo sapiens chromobox homolog 5 (CBX5), transcript variant 1, mRNA PA
NM_001127321.1 Homo sapiens chromobox homolog 5 (CBX5), transcript variant 2, mRNA PA
AK095108.1 Homo sapiens cDNA FLJ37789 fis, clone BRHIP3000081
BC030149.2 Homo sapiens cDNA clone IMAGE:4842353, partial cds A
AF147443.1 Homo sapiens full length insert cDNA clone ZC65B08
S62077.1 HP1Hs alpha=25 kda chromosomal autoantigen [human, mRNA, 876 nt] PA
U26311.1 Human heterochromatin protein HP1Hs-alpha mRNA, partial cds P
L07515.1 Human heterochromatin protein homologue (HP1) mRNA, complete cds P

EST sequences (10 of 965) [Show all sequences]

AA954164.1 Clone IMAGE:1591330 kidney 3' read
AA954203.1 Clone IMAGE:1575079 kidney 3' read A
AA948055.1 Clone IMAGE:1416070 lung 3' read
AA962433.1 Clone IMAGE:1553554 kidney 3' read
AA973157.1 Clone IMAGE:1564233 mixed 3' read
AA978268.1 Clone IMAGE:1579871 mixed 3' read A
AA983926.1 Clone IMAGE:1583325 mixed 3' read A
AA988044.1 Clone IMAGE:1605168 lung 3' read A
AA988340.1 Clone IMAGE:1605550 kidney 3' read
AI014770.1 Clone IMAGE:1611186 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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