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UGID:190779     UniGene Hs.335061     Homo sapiens (human)   COPS7B
COP9 signalosome subunit 7B (COPS7B)

Human protein-coding gene COPS7B. Represented by 479 ESTs from 200 cDNA libraries. Corresponds to reference sequence NM_022730.1. [UniGene 190779 - Hs.335061]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003908127.1 PREDICTED: COP9 signalosome complex subunit 7b isoform 2 P. anubis 100.0 272
XP_001113929.1 PREDICTED: COP9 signalosome complex subunit 7b-like isoform 10 M. mulatta 100.0 263
XP_001145849.1 PREDICTED: COP9 signalosome complex subunit 7b isoform 13 P. troglodytes 100.0 263
NP_073567.1 COPS7B gene product H. sapiens 100.0 263
XP_852665.1 PREDICTED: COP9 signalosome complex subunit 7b isoform 2 C. lupus familiaris 100.0 263
NP_001040077.1 COPS7B gene product B. taurus 100.0 263
XP_002712568.1 PREDICTED: COP9 constitutive photomorphogenic homolog subunit 7B O. cuniculus 100.0 263
XP_001498559.1 PREDICTED: COP9 signalosome complex subunit 7b-like E. caballus 99.6 263
NP_001156034.1 COPS7B gene product O. aries 99.6 263
NP_766562.1 COP9 signalosome complex subunit 7b M. musculus 98.9 263
NP_001089653.1 COP9 constitutive photomorphogenic homolog subunit 7B X. laevis 89.0 263
NP_610379.2 COP9 complex homolog subunit 7 D. melanogaster 52.5 244
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
NP_001102277.1 Cops7b gene product R. norvegicus 95.9 316
XP_001362958.1 PREDICTED: COP9 signalosome complex subunit 7b-like M. domestica 95.8 263

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; thymus; adrenal gland; umbilical cord; skin; cervix; spleen; heart; connective tissue; uterus; bladder; lung; embryonic tissue; muscle; intestine; placenta; kidney; blood; mixed; prostate; salivary gland; esophagus; vascular; trachea; liver; eye; ovary; mammary gland; mouth; pancreas; ascites; bone; thyroid; tonsil; bone marrow; stomach; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q37.1
UniSTS entry: Chr 2 RH45929
UniSTS entry: Chr 2 AB060239
UniSTS entry: Chr 2 RH47930
UniSTS entry: Chr 2 COPS7B_v483
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 1 D8S2278
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK126326.1 Homo sapiens cDNA FLJ44352 fis, clone TRACH3006412, highly similar to Homo sapiens COP9 constitutive photomorphogenic homolog subunit 7B P
AK124133.1 Homo sapiens cDNA FLJ42139 fis, clone TESTI2039025, highly similar to COP9 signalosome complex subunit 7b P
BC091493.1 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis), mRNA (cDNA clone MGC:111077 IMAGE:30387712), complete cds PA
AK222879.1 Homo sapiens mRNA for COP9 constitutive photomorphogenic homolog subunit 7B variant, clone: HEP18884 PA
AK022674.1 Homo sapiens cDNA FLJ12612 fis, clone NT2RM4001582, highly similar to Mus musculus COP9 complex subunit 7b (COPS7b) mRNA P
AK024273.1 Homo sapiens cDNA FLJ14211 fis, clone NT2RP3003411, highly similar to Mus musculus COP9 complex subunit 7b (COPS7b) mRNA P
NM_022730.1 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) (COPS7B), mRNA P
BC010739.1 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis), mRNA (cDNA clone IMAGE:3893022), partial cds PA
AK307486.1 Homo sapiens cDNA, FLJ97434 P
AK098334.1 Homo sapiens cDNA FLJ41015 fis, clone UTERU2018712, highly similar to COP9 signalosome complex subunit 7b P

EST sequences (10 of 479) [Show all sequences]

AA976575.1 Clone IMAGE:1558667 lung 3' read A
AA976999.1 Clone IMAGE:1558691 lung 3' read A
AA887519.1 Clone IMAGE:1500521 lung 3' read P
AI122711.1 Clone IMAGE:1672101 uncharacterized tissue 3' read A
AI150525.1 Clone IMAGE:1752622 testis 3' read A
AI167181.1 Clone IMAGE:1509150 mixed 3' read
BX098394.1 Clone IMAGp998O241937_;_IMAGE:786287 embryonic tissue A
CB117191.1 Clone L4SNU368-29-C10 liver 5' read
CB152931.1 Clone B1T694954-16-E10 brain 5' read P
CB154666.1 Clone B2N807043-29-H09 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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