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UGID:189096     UniGene Hs.331420     Homo sapiens (human)   PPAT
Phosphoribosyl pyrophosphate amidotransferase (PPAT)

Human protein-coding gene PPAT. Represented by 289 ESTs from 161 cDNA libraries. Corresponds to reference sequence NM_002703.4. [UniGene 189096 - Hs.331420]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002694.3 PPAT gene product H. sapiens 100.0 516
XP_001085606.1 PREDICTED: amidophosphoribosyltransferase M. mulatta 99.8 516
XP_003898910.1 PREDICTED: amidophosphoribosyltransferase P. anubis 99.8 516
XP_001140991.1 PREDICTED: amidophosphoribosyltransferase isoform 2 P. troglodytes 99.8 516
NP_742158.1 phosphoribosyl pyrophosphate amidotransferase M. musculus 95.2 516
NP_001083491.1 phosphoribosyl pyrophosphate amidotransferase X. laevis 87.0 507
NP_001076346.2 ppat gene product D. rerio 80.7 507
NP_524271.2 phosphoribosylamidotransferase, isoform A D. melanogaster 66.0 523
NP_497958.1 Protein T04A8.5 C. elegans 50.6 478
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_002717208.1 PREDICTED: phosphoribosyl pyrophosphate amidotransferase O. cuniculus 97.3 515
XP_004009890.1 PREDICTED: amidophosphoribosyltransferase O. aries 96.7 520

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mixed; placenta; uncharacterized tissue; ovary; embryonic tissue; lung; eye; uterus; muscle; skin; pancreas; kidney; lymph node; mammary gland; mouth; bladder; thyroid; esophagus; trachea; lymph; thymus; prostate; connective tissue; liver; blood; intestine; bone; bone marrow; vascular; ear; salivary gland; stomach; heart; cervix
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q12
UniSTS entry: Chr 3 WI-20631 [Map Viewer]
UniSTS entry: Chr 4 D4S3143 [Map Viewer]
UniSTS entry: Chr 3 RH70521
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_002703.4 Homo sapiens phosphoribosyl pyrophosphate amidotransferase (PPAT), mRNA PA
AB209246.1 Homo sapiens mRNA for phosphoribosyl pyrophosphate amidotransferase proprotein variant protein P
AK222759.1 Homo sapiens mRNA for phosphoribosyl pyrophosphate amidotransferase proprotein variant, clone: HEP00145 P
BC004200.2 Homo sapiens phosphoribosyl pyrophosphate amidotransferase, mRNA (cDNA clone MGC:3674 IMAGE:3533162), complete cds PA
AK290942.1 Homo sapiens cDNA FLJ78123 complete cds, highly similar to Homo sapiens phosphoribosyl pyrophosphate amidotransferase (PPAT), mRNA P
U00238.1 Homo sapiens glutamine PRPP amidotransferase (GPAT) mRNA, complete cds PA
AK312297.1 Homo sapiens cDNA, FLJ92602, highly similar to Homo sapiens phosphoribosyl pyrophosphate amidotransferase (PPAT), mRNA P
D13757.1 Homo sapiens mRNA for amidophosphoribosyltransferase, complete cds P

EST sequences (10 of 289) [Show all sequences]

R14451.1 Clone IMAGE:29038 brain 5' read
R14868.1 Clone IMAGE:129528 mixed 3' read
R16818.1 Clone IMAGE:128700 mixed 3' read
AA927872.1 Clone IMAGE:1541361 mixed 3' read A
AI025457.1 Clone IMAGE:1641421 testis 3' read
R21723.1 Clone IMAGE:130354 placenta 3' read
CB044540.1 Clone IMAGE:3217852 intestine 3' read A
CB044541.1 Clone IMAGE:3217852 intestine 5' read P
R24877.1 Clone IMAGE:131982 placenta 5' read
BX100085.1 Clone IMAGp998M07660_;_IMAGE:295854 mixed

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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