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UGID:188621     UniGene Hs.330386     Homo sapiens (human)   CHRNB1
Cholinergic receptor, nicotinic, beta 1 (muscle) (CHRNB1)

Human protein-coding gene CHRNB1. Represented by 99 ESTs from 63 cDNA libraries. Corresponds to reference sequence NM_000747.2. [UniGene 188621 - Hs.330386]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000738.2 CHRNB1 gene product H. sapiens 100.0 500
XP_511298.3 PREDICTED: acetylcholine receptor subunit beta isoform 2 P. troglodytes 99.6 500
NP_033731.3 Chrnb1 gene product M. musculus 92.2 500
XP_001341867.1 PREDICTED: acetylcholine receptor subunit beta D. rerio 64.9 472
NP_491533.2 Protein UNC-63 C. elegans 50.7 144
NP_523927.2 nicotinic acetylcholine receptor beta 64B, isoform A D. melanogaster 49.0 350
NP_001095267.1 acetylcholine receptor subunit delta precursor X. laevis 48.6 391
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003912300.1 PREDICTED: LOW QUALITY PROTEIN: acetylcholine receptor subunit beta P. anubis 98.2 501
XP_001108848.2 PREDICTED: acetylcholine receptor subunit beta M. mulatta 98.0 441

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; muscle; stomach; embryonic tissue; kidney; testis; mammary gland; mouth; pharynx; placenta; prostate; blood; heart; pancreas; uncharacterized tissue; uterus; intestine; amniotic fluid; thyroid; thymus; skin; eye; liver; mixed; lymph; spleen; ovary
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13.1
UniSTS entry: Chr 17 STS-X14830 [Map Viewer]
UniSTS entry: Chr 17 IB1796 [Map Viewer]
UniSTS entry: Chr 1 D11S2612
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_000747.2 Homo sapiens cholinergic receptor, nicotinic, beta 1 (muscle) (CHRNB1), mRNA P
BC011371.1 Homo sapiens cholinergic receptor, nicotinic, beta 1 (muscle), mRNA (cDNA clone MGC:9005 IMAGE:3874415), complete cds PA
AK308106.1 Homo sapiens cDNA, FLJ98054 P
X14830.1 Human mRNA for muscle acetylcholine receptor beta-subunit P
AK298938.1 Homo sapiens cDNA FLJ52354 complete cds, highly similar to Acetylcholine receptor protein subunit beta precursor P
BC023553.2 Homo sapiens cholinergic receptor, nicotinic, beta 1 (muscle), mRNA (cDNA clone MGC:19706 IMAGE:3531876), complete cds PA

EST sequences (10 of 99) [Show all sequences]

BX110786.1 Clone IMAGp998E13141_;_IMAGE:26992 brain A
CB141884.1 Clone L11SNU354s1-2-C08 liver 5' read
R36983.1 Clone IMAGE:26992 brain 3' read A
CB992791.1 Clone IMAGE:30333682 placenta 5' read P
CB994947.1 Clone IMAGE:30335132 placenta 5' read P
AI868407.1 Clone IMAGE:2146723 mixed 3' read
BX500607.1 Clone DKFZp779J2257 liver 5' read P
CD691168.1 pharynx P
CD699958.1 pharynx P
AW062966.1 stomach

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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