NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:188411     UniGene Hs.329327     Homo sapiens (human)   TNKS2
Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2)

Human protein-coding gene TNKS2. Represented by 280 ESTs from 167 cDNA libraries. Corresponds to reference sequence NM_025235.3. [UniGene 188411 - Hs.329327]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003312726.2 PREDICTED: LOW QUALITY PROTEIN: tankyrase-2 P. troglodytes 100.0 1289
NP_079511.1 TNKS2 gene product H. sapiens 100.0 1165
XP_002805803.1 PREDICTED: tankyrase-2-like M. mulatta 99.9 1165
XP_003904040.1 PREDICTED: tankyrase-2 P. anubis 99.9 1165
XP_001926591.3 PREDICTED: tankyrase-2 S. scrofa 99.9 1165
XP_001502731.2 PREDICTED: tankyrase-2 E. caballus 99.6 1166
XP_003640030.1 PREDICTED: tankyrase-2-like C. lupus familiaris 99.6 1165
NP_001157107.1 Tnks2 gene product M. musculus 98.3 1165
XP_687410.2 PREDICTED: tankyrase-1 D. rerio 87.2 1197
NP_001088420.1 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 X. laevis 86.2 1213
NP_651410.1 tankyrase, isoform A D. melanogaster 73.0 1152
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_002718552.1 PREDICTED: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2-like O. cuniculus 99.3 1165
XP_002698425.1 PREDICTED: tankyrase-2 B. taurus 99.2 1148

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; mixed; uncharacterized tissue; prostate; amniotic fluid; mouth; intestine; pancreas; mammary gland; larynx; adrenal gland; pharynx; adipose tissue; vascular; testis; embryonic tissue; lung; liver; eye; kidney; thymus; uterus; muscle; stomach; lymph node; trachea; bone; blood; skin; ear; lymph; ascites; connective tissue; thyroid; ovary; spleen; nerve; pituitary gland; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.3
UniSTS entry: Chr 10 D10S2170
UniSTS entry: Chr 10 R58932
UniSTS entry: Chr 10 RH45093
UniSTS entry: Chr 10 WI-16054 [Map Viewer]
UniSTS entry: Chr 10 RH68352
UniSTS entry: Chr 10 NIB351 [Map Viewer]
UniSTS entry: Chr 10 RH78232
UniSTS entry: D11S2591
UniSTS entry: D11S2920
UniSTS entry: Chr 10 SHGC-53837
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK023746.1 Homo sapiens cDNA FLJ13684 fis, clone PLACE2000021, moderately similar to Homo sapiens TRF1-interacting ankyrin-related ADP-ribose polymerase mRNA P
AF305081.1 Homo sapiens tankyrase-related protein mRNA, partial cds PA
AF264912.1 Homo sapiens tankyrase-like protein (TNKL) mRNA, complete cds PA
AF342982.1 Homo sapiens tankyrase 2 mRNA, complete cds P
NM_025235.3 Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2), mRNA P
AF329696.1 Homo sapiens tankyrase 2 mRNA, complete cds P
AF309033.1 Homo sapiens tankyrase-2 (TNKS-2) mRNA, complete cds P
AF438201.1 Homo sapiens tankyrase II mRNA, complete cds PA
AK314612.1 Homo sapiens cDNA, FLJ95451, highly similar to Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2), mRNA P
AL833676.1 Homo sapiens mRNA; cDNA DKFZp667A1222 (from clone DKFZp667A1222) PA
BC023218.1 Homo sapiens, clone IMAGE:4933444, mRNA PA

EST sequences (10 of 280) [Show all sequences]

R14158.1 Clone IMAGE:28616 brain 5' read
AA864829.1 Clone IMAGE:1460064 kidney 3' read A
AA970617.1 Clone IMAGE:1579351 mixed 3' read
AA995110.1 Clone IMAGE:1625812 mixed 3' read
AI003014.1 Clone IMAGE:1684248 brain 3' read
AI040839.1 Clone IMAGE:1657579 embryonic tissue 3' read
R19912.1 Clone IMAGE:34716 brain 5' read
CB048534.1 Clone IMAGE:3270948 prostate 5' read
CB048533.1 Clone IMAGE:3270948 prostate 3' read A
BX103336.1 Clone IMAGp998K11202_;_IMAGE:139138 placenta


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help