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UGID:188411     UniGene Hs.329327     Homo sapiens (human)   TNKS2
Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2)

Human protein-coding gene TNKS2. Represented by 280 ESTs from 167 cDNA libraries. Corresponds to reference sequence NM_025235.3. [UniGene 188411 - Hs.329327]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003312726.2 PREDICTED: LOW QUALITY PROTEIN: tankyrase-2 P. troglodytes 100.0 1289
NP_079511.1 TNKS2 gene product H. sapiens 100.0 1165
XP_002805803.1 PREDICTED: tankyrase-2-like M. mulatta 99.9 1165
XP_003904040.1 PREDICTED: tankyrase-2 P. anubis 99.9 1165
XP_001926591.3 PREDICTED: tankyrase-2 S. scrofa 99.9 1165
XP_001502731.2 PREDICTED: tankyrase-2 E. caballus 99.6 1166
XP_003640030.1 PREDICTED: tankyrase-2-like C. lupus familiaris 99.6 1165
NP_001157107.1 Tnks2 gene product M. musculus 98.3 1165
XP_687410.2 PREDICTED: tankyrase-1 D. rerio 87.2 1197
NP_001088420.1 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 X. laevis 86.2 1213
NP_651410.1 tankyrase, isoform A D. melanogaster 73.0 1152
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_002718552.1 PREDICTED: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2-like O. cuniculus 99.3 1165
XP_002698425.1 PREDICTED: tankyrase-2 B. taurus 99.2 1148

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; mixed; uncharacterized tissue; prostate; amniotic fluid; mouth; intestine; pancreas; mammary gland; larynx; adrenal gland; pharynx; adipose tissue; vascular; testis; embryonic tissue; lung; liver; eye; kidney; thymus; uterus; muscle; stomach; lymph node; trachea; bone; blood; skin; ear; lymph; ascites; connective tissue; thyroid; ovary; spleen; nerve; pituitary gland; heart
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.3
UniSTS entry: Chr 10 D10S2170
UniSTS entry: Chr 10 R58932
UniSTS entry: Chr 10 RH45093
UniSTS entry: Chr 10 WI-16054 [Map Viewer]
UniSTS entry: Chr 10 RH68352
UniSTS entry: Chr 10 NIB351 [Map Viewer]
UniSTS entry: Chr 10 RH78232
UniSTS entry: D11S2591
UniSTS entry: D11S2920
UniSTS entry: Chr 10 SHGC-53837
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK023746.1 Homo sapiens cDNA FLJ13684 fis, clone PLACE2000021, moderately similar to Homo sapiens TRF1-interacting ankyrin-related ADP-ribose polymerase mRNA P
AF305081.1 Homo sapiens tankyrase-related protein mRNA, partial cds PA
AF264912.1 Homo sapiens tankyrase-like protein (TNKL) mRNA, complete cds PA
AF342982.1 Homo sapiens tankyrase 2 mRNA, complete cds P
NM_025235.3 Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2), mRNA P
AF329696.1 Homo sapiens tankyrase 2 mRNA, complete cds P
AF309033.1 Homo sapiens tankyrase-2 (TNKS-2) mRNA, complete cds P
AF438201.1 Homo sapiens tankyrase II mRNA, complete cds PA
AK314612.1 Homo sapiens cDNA, FLJ95451, highly similar to Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2), mRNA P
AL833676.1 Homo sapiens mRNA; cDNA DKFZp667A1222 (from clone DKFZp667A1222) PA
BC023218.1 Homo sapiens, clone IMAGE:4933444, mRNA PA

EST sequences (10 of 280) [Show all sequences]

R14158.1 Clone IMAGE:28616 brain 5' read
AA864829.1 Clone IMAGE:1460064 kidney 3' read A
AA970617.1 Clone IMAGE:1579351 mixed 3' read
AA995110.1 Clone IMAGE:1625812 mixed 3' read
AI003014.1 Clone IMAGE:1684248 brain 3' read
AI040839.1 Clone IMAGE:1657579 embryonic tissue 3' read
R19912.1 Clone IMAGE:34716 brain 5' read
CB048534.1 Clone IMAGE:3270948 prostate 5' read
CB048533.1 Clone IMAGE:3270948 prostate 3' read A
BX103336.1 Clone IMAGp998K11202_;_IMAGE:139138 placenta

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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