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UGID:184126     UniGene Hs.313056     Homo sapiens (human)   TWF1
Twinfilin, actin-binding protein, homolog 1 (Drosophila) (TWF1)

Human protein-coding gene TWF1. Represented by 151 ESTs from 84 cDNA libraries. EST representation biased toward neonate. [UniGene 184126 - Hs.313056]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001165727.2 PREDICTED: twinfilin-1 isoform 5 P. troglodytes 100.0 383
NP_002813.3 TWF1 gene product H. sapiens 100.0 349
NP_032997.3 Twf1 gene product M. musculus 96.3 349
NP_001087483.1 twinfilin-1 X. laevis 82.3 349
NP_001002304.1 twf1b gene product D. rerio 78.5 344
NP_650338.1 twinfilin D. melanogaster 49.4 342
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_003906279.1 PREDICTED: twinfilin-1 isoform 1 P. anubis 99.5 383
XP_543726.2 PREDICTED: twinfilin-1 isoform 1 C. lupus familiaris 98.9 349

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; intestine; esophagus; adrenal gland; kidney; uterus; skin; pancreas; eye; mammary gland; mouth; placenta; vascular; pharynx; blood; connective tissue; lymph node; embryonic tissue; uncharacterized tissue; mixed; thymus; lung; cervix; trachea; liver; ascites; heart; pituitary gland; nerve; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 12q12
UniSTS entry: RH143291
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

CR541761.1 Homo sapiens full open reading frame cDNA clone RZPDo834D0130D for gene PTK9, PTK9 protein tyrosine kinase 9; complete cds, without stopcodon P
CR541736.1 Homo sapiens full open reading frame cDNA clone RZPDo834F0129D for gene PTK9, PTK9 protein tyrosine kinase 9; complete cds, incl. stopcodon P
BT019691.1 Homo sapiens PTK9 protein tyrosine kinase 9 mRNA, complete cds P
AK291223.1 Homo sapiens cDNA FLJ77129 complete cds, highly similar to Homo sapiens PTK9 protein tyrosine kinase 9 mRNA P

EST sequences (10 of 151) [Show all sequences]

AI279167.1 Clone IMAGE:1882234 lung 3' read P
AI290846.1 Clone IMAGE:1881226 lung 3' read P
AI400130.1 Clone IMAGE:2113361 mixed 3' read PA
AU280521.1 Clone N1ESE2002394 uncharacterized tissue 5' read P
AL036933.3 Clone DKFZp564C1264 brain 5' read P
AL036939.3 Clone DKFZp564C1864 brain 5' read P
AL048603.1 Clone DKFZp586N102 uterus P
CB990270.1 Clone IMAGE:30346906 placenta 5' read P
CB990367.1 Clone IMAGE:30340604 placenta 5' read P
CD513129.1 Clone IMAGE:30394028 pituitary gland 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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