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UGID:181829     UniGene Hs.303649     Homo sapiens (human)   CCL2
Chemokine (C-C motif) ligand 2 (CCL2)

Human protein-coding gene CCL2. Represented by 276 ESTs from 125 cDNA libraries. Corresponds to reference sequence NM_002982.3. [UniGene 181829 - Hs.303649]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001174551.1 PREDICTED: c-C motif chemokine 2 isoform 2 P. troglodytes 100.0 98
NP_002973.1 CCL2 gene product H. sapiens 100.0 98
Other hits (2 of 7) [Show all]SpeciesId(%)Len(aa)
NP_001027993.1 CCL2 gene product M. mulatta 99.0 98
NP_001167009.1 CCL2 gene product P. anubis 99.0 98

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; lung; mixed; blood; uncharacterized tissue; placenta; eye; kidney; brain; intestine; amniotic fluid; testis; vascular; pharynx; mammary gland; bladder; bone marrow; larynx; connective tissue; stomach; liver; adrenal gland; prostate; skin; muscle; heart; bone; embryonic tissue; adipose tissue; uterus; parathyroid; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q11.2-q12
UniSTS entry: Chr 17 D17S1269
UniSTS entry: Chr 17 GDB:607769
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BT007329.1 Homo sapiens chemokine (C-C motif) ligand 2 mRNA, complete cds P
NM_002982.3 Homo sapiens chemokine (C-C motif) ligand 2 (CCL2), mRNA PA
M28226.1 Human JE gene encoding a monocyte secretory protein mRNA, complete cds P
BC009716.1 Homo sapiens chemokine (C-C motif) ligand 2, mRNA (cDNA clone MGC:9434 IMAGE:3901489), complete cds PA
X14768.1 H.sapiens mRNA for monocyte chemoattractant protein 1 (MCP-1) P
AK311960.1 Homo sapiens cDNA, FLJ92229, Homo sapiens chemokine (C-C motif) ligand 2 (CCL2), mRNA P
AK311308.1 Homo sapiens cDNA, FLJ18350
M24545.1 Human monocyte chemotactic and activating factor (MCAF) mRNA, complete cds P
S71513.1 monocyte chemoattractant protein-1 [human, mRNA, 739 nt] PA
S69738.1 MCP-1=monocyte chemotactic protein [human, aortic endothelial cells, mRNA, 661 nt] P

EST sequences (10 of 276) [Show all sequences]

AA961456.1 Clone IMAGE:1599597 uncharacterized tissue 3' read A
AA972758.1 Clone IMAGE:1585081 lung 3' read A
AA973071.1 Clone IMAGE:1578498 mixed 3' read A
AA991932.1 Clone IMAGE:1613451 uncharacterized tissue 3' read PA
AI042416.1 Clone IMAGE:1665017 skin 3' read A
AI075862.1 Clone IMAGE:1676343 embryonic tissue 3' read A
AI097531.1 Clone IMAGE:1707127 heart 3' read A
BX113566.1 Clone IMAGp998L2280_;_IMAGE:108837 mixed P
AI263030.1 Clone IMAGE:2028838 kidney 3' read A
R31199.1 Clone IMAGE:134367 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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