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UGID:131335     UniGene Hs.3003     Homo sapiens (human)   CD3E
CD3e molecule, epsilon (CD3-TCR complex) (CD3E)

Human protein-coding gene CD3E. Represented by 111 ESTs from 53 cDNA libraries. EST representation biased toward juvenile. Corresponds to reference sequence NM_000733.3. [UniGene 131335 - Hs.3003]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000724.1 CD3E gene product H. sapiens 100.0 206
XP_001160742.1 PREDICTED: T-cell surface glycoprotein CD3 epsilon chain isoform 3 P. troglodytes 99.5 206
NP_031674.1 Cd3e gene product M. musculus 73.0 188
Other hits (2 of 10) [Show all]SpeciesId(%)Len(aa)
XP_001097204.1 PREDICTED: t-cell surface glycoprotein CD3 epsilon chain M. mulatta 90.4 197
XP_003910825.1 PREDICTED: T-cell surface glycoprotein CD3 epsilon chain P. anubis 90.4 197

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: juvenile [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; thymus; lung; brain; heart; mixed; spleen; pharynx; liver; intestine; mouth; trachea; tonsil; pancreas; uterus; mammary gland; uncharacterized tissue; kidney; lymph node; placenta; eye; connective tissue
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23
UniSTS entry: Chr 11 D11S4380
UniSTS entry: Chr 11 RH18074
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

BC049847.1 Homo sapiens CD3e molecule, epsilon (CD3-TCR complex), mRNA (cDNA clone MGC:51948 IMAGE:5214563), complete cds PA
NM_000733.3 Homo sapiens CD3e molecule, epsilon (CD3-TCR complex) (CD3E), mRNA PA
AK292612.1 Homo sapiens cDNA FLJ76365 complete cds, highly similar to Homo sapiens CD3E antigen, epsilon polypeptide (TiT3 complex) (CD3E), mRNA PA
AK091285.1 Homo sapiens cDNA FLJ33966 fis, clone CTONG2019144 P
AK301255.1 Homo sapiens cDNA FLJ59770 complete cds, highly similar to T-cell surface glycoprotein CD3 epsilon chain precursor P
X03884.1 Human mRNA for T3 epsilon chain (20K) of T-cell receptor (from peripheral blood lymphocytes) P

EST sequences (10 of 111) [Show all sequences]

AA283293.1 thymus
AI300869.1 Clone IMAGE:1900479 kidney 3' read
BX362258.2 Clone CS0DJ012YI24 blood 5' read P
BX421687.2 Clone CS0DH003YM06 blood 5' read P
BX421803.2 Clone CS0DH004YD09 blood 5' read P
BX421625.2 Clone CS0DH002YD08 blood 5' read P
BX444247.2 Clone CS0DM014YI22 liver 5' read P
BX431986.2 Clone CS0DM014YI22 liver 5' read P
BX436406.1 Clone CS0CAP001YJ15 thymus 3' read
BX436407.2 Clone CS0CAP001YJ15 thymus 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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