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UGID:180316     UniGene Hs.295917     Homo sapiens (human)   ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ATP6V1B2)

Human protein-coding gene ATP6V1B2. Represented by 1028 ESTs from 288 cDNA libraries. Corresponds to reference sequence NM_001693.3. [UniGene 180316 - Hs.295917]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001100869.1 PREDICTED: v-type proton ATPase subunit B, brain isoform M. mulatta 100.0 533
XP_003902538.1 PREDICTED: V-type proton ATPase subunit B, brain isoform P. anubis 100.0 533
XP_519638.2 PREDICTED: V-type proton ATPase subunit B, brain isoform P. troglodytes 100.0 510
NP_001684.2 ATP6V1B2 gene product H. sapiens 100.0 510
XP_003483427.1 PREDICTED: V-type proton ATPase subunit B, brain isoform S. scrofa 100.0 510
NP_788844.2 ATP6V1B2 gene product B. taurus 100.0 510
XP_004004266.1 PREDICTED: V-type proton ATPase subunit B, brain isoform O. aries 100.0 510
NP_031535.2 Atp6v1b2 gene product M. musculus 99.8 510
NP_476561.1 Atp6v1b2 gene product R. norvegicus 99.8 510
XP_543263.2 PREDICTED: V-type proton ATPase subunit B, brain isoform isoform 1 C. lupus familiaris 99.8 510
XP_002716916.1 PREDICTED: ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 O. cuniculus 99.8 510
XP_001489715.2 PREDICTED: v-type proton ATPase subunit B, brain isoform-like E. caballus 99.6 482
NP_001080613.1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 X. laevis 98.2 510
NP_878299.1 atp6v1b2 gene product D. rerio 97.6 508
NP_476908.1 vacuolar H[+]-ATPase 55kD B subunit, isoform B D. melanogaster 95.5 488
NP_508711.1 Protein VHA-12 C. elegans 92.7 477
NP_009685.3 Vma2p S. cerevisiae 88.5 477
NP_173451.5 V-type proton ATPase subunit B3 A. thaliana 87.9 486
XP_963165.1 vacuolar ATP synthase subunit B N. crassa 86.9 481
XP_001701846.1 vacuolar ATP synthase subunit B C. reinhardtii 86.8 485
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_424534.3 PREDICTED: V-type proton ATPase subunit B, brain isoform G. gallus 99.0 505
XP_003212467.1 PREDICTED: v-type proton ATPase subunit B, brain isoform-like M. gallopavo 99.0 484

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; eye; skin; pancreas; kidney; mixed; lung; mammary gland; embryonic tissue; blood; adipose tissue; pituitary gland; placenta; ovary; heart; uterus; intestine; connective tissue; bone marrow; liver; thymus; nerve; prostate; thyroid; vascular; spleen; esophagus; trachea; bladder; lymph; ascites; stomach; muscle; mouth; bone; lymph node; parathyroid; pharynx; cervix; pineal gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21.3
UniSTS entry: Chr 8 RH118507
UniSTS entry: Chr 8 D8S1949
UniSTS entry: Chr 8 ATP6V1B2_8221
UniSTS entry: Chr 8 RH44158 [Map Viewer]
UniSTS entry: Chr 8 WI-19010 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_001693.3 Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ATP6V1B2), mRNA PA
L35249.1 Homo sapiens vacuolar H+-ATPase Mr 56,000 subunit (HO57) mRNA, complete cds P
BC003100.1 Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, mRNA (cDNA clone MGC:1797 IMAGE:3502278), complete cds PA
BC007309.1 Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, mRNA (cDNA clone IMAGE:3352651), partial cds PA
AK312372.1 Homo sapiens cDNA, FLJ92695, Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1subunit B, isoform 2 (ATP6V1B2), mRNA P
BC030640.2 Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, mRNA (cDNA clone MGC:26702 IMAGE:4821062), complete cds PA
AK294163.1 Homo sapiens cDNA FLJ51779 complete cds, highly similar to Vacuolar ATP synthase subunit B, brain isoform (EC 3.6.3.14) P
AK298819.1 Homo sapiens cDNA FLJ53854 complete cds, highly similar to Vacuolar ATP synthase subunit B, brain isoform (EC 3.6.3.14) P
X62949.1 H.sapiens mRNA for isoform 2 of vacuolar H+ATPase Mr 56,000 subunit P

EST sequences (10 of 1028) [Show all sequences]

AA961952.1 Clone IMAGE:1593789 kidney 3' read
R16582.1 Clone IMAGE:129661 mixed 3' read
AI000609.1 Clone IMAGE:1610056 mammary gland 3' read A
AA904598.1 Clone IMAGE:1503822 mixed 3' read A
AI003179.1 Clone IMAGE:1699642 kidney 3' read A
AI027782.1 Clone IMAGE:1645481 testis 3' read A
AI034280.1 Clone IMAGE:1663532 skin 3' read A
AI039172.1 Clone IMAGE:1657952 embryonic tissue 3' read A
AI056349.1 Clone IMAGE:1669050 brain 3' read A
AI076136.1 Clone IMAGE:1673313 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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