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UGID:177032     UniGene Hs.284255     Homo sapiens (human)   ALPP
Alkaline phosphatase, placental (ALPP)

Human protein-coding gene ALPP. Represented by 109 ESTs from 35 cDNA libraries. EST representation biased toward placenta; adult. Corresponds to reference sequence NM_001632.3. [UniGene 177032 - Hs.284255]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_002721502.1 PREDICTED: intestinal alkaline phosphatase O. cuniculus 76.0 237
NP_001623.3 ALPP gene product H. sapiens 75.9 417
XP_001495497.2 PREDICTED: intestinal-type alkaline phosphatase-like E. caballus 75.8 161
NP_031459.3 alkaline phosphatase, placental-like precursor M. musculus 71.2 160
NP_001091135.1 alkaline phosphatase, intestinal, gene 1 precursor X. laevis 57.9 159
NP_957301.1 alpl gene product D. rerio 56.0 159
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_001146156.2 PREDICTED: alkaline phosphatase, placental type isoform 1 P. troglodytes 75.2 417
XP_003359722.1 PREDICTED: intestinal-type alkaline phosphatase-like S. scrofa 75.0 148

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: placenta [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; esophagus; amniotic fluid; intestine; mixed; heart; uterus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q37
UniSTS entry: Chr 2 A002R47
UniSTS entry: Chr 2 GDB:216786
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_001632.3 Homo sapiens alkaline phosphatase, placental (ALPP), mRNA
M12551.1 Human placental alkaline phosphatase (PLAP) mRNA, complete cds
M14169.1 Human placental alkaline phosphatase type 1 mRNA
M14170.1 Human placental alkaline phosphatase type 3 mRNA
BC068501.1 Homo sapiens alkaline phosphatase, placental (Regan isozyme), mRNA (cDNA clone MGC:87242 IMAGE:30349481), complete cds A
BC094743.1 Homo sapiens alkaline phosphatase, placental (Regan isozyme), mRNA (cDNA clone MGC:104591 IMAGE:30330997), complete cds A
AF217992.1 Homo sapiens clone PP1740 unknown mRNA A
BC009647.1 Homo sapiens alkaline phosphatase, placental (Regan isozyme), mRNA (cDNA clone MGC:5096 IMAGE:3460735), complete cds A
AK075432.1 Homo sapiens cDNA PSEC0123 fis, clone PLACE1003344, highly similar to ALKALINE PHOSPHATASE, PLACENTAL TYPE 1 PRECURSOR (EC 3.1.3.1)

EST sequences (10 of 109) [Show all sequences]

R23943.1 Clone IMAGE:131419 placenta 3' read
BX095665.1 Clone IMAGp998I20182_;_IMAGE:131419 placenta A
R26571.1 Clone IMAGE:131772 placenta 3' read
R31098.1 Clone IMAGE:134234 placenta 3' read
R31146.1 Clone IMAGE:134234 placenta 5' read
R31392.1 Clone IMAGE:135602 placenta 5' read
R32889.1 Clone IMAGE:135602 placenta 3' read A
AI457757.1 Clone IMAGE:2144836 mixed 3' read
AI538358.1 Clone IMAGE:2204097 uterus 3' read
CB959579.1 Clone IMAGE:30345939 placenta 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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