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UGID:176250     UniGene Hs.282624     Homo sapiens (human)   CYP2C9
Cytochrome P450, family 2, subfamily C, polypeptide 9 (CYP2C9)

Human protein-coding gene CYP2C9. Represented by 189 ESTs from 27 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_000771.3. [UniGene 176250 - Hs.282624]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000762.2 CYP2C9 gene product H. sapiens 100.0 489
XP_003339236.1 PREDICTED: cytochrome P450 2C9-like isoform 1 P. troglodytes 99.6 489
NP_031841.3 Cyp2c29 gene product M. musculus 81.0 489
NP_001085245.1 cytochrome P450, family 2, subfamily C, polypeptide 18 X. laevis 58.6 486
XP_001923597.2 PREDICTED: cytochrome P450 2G1-like D. rerio 52.5 488
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
NP_001035301.1 CYP2C75 gene product M. mulatta 95.7 489
XP_001502280.1 PREDICTED: cytochrome P450 2C27-like isoform 1 E. caballus 85.5 489

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; connective tissue; mammary gland; uncharacterized tissue; muscle; mixed; intestine; kidney; uterus; lung
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24
UniSTS entry: Chr 10 GDB:193845
UniSTS entry: Chr 10 RH45236
UniSTS entry: Chr 10 SGC35305 [Map Viewer]
UniSTS entry: Chr 10 D10S2360
UniSTS entry: D10S2358
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC070317.1 Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9, mRNA (cDNA clone IMAGE:4722940), complete cds PA
M15331.1 Human liver cytochrome P-450 S-mephenytoin 4-hydroxylase (P-450mp) mRNA, partial cds P
M21940.1 Human cytochrome P-450 S-mephenytoin 4-hydroxylase (P-450mp) mRNA, 3' end, clone MP-4 P
D00173.1 Homo sapiens mRNA for cytochrome P-450, partial cds P
NM_000771.3 Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 (CYP2C9), mRNA PA
BC125054.1 Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9, mRNA (cDNA clone MGC:149605 IMAGE:40116637), complete cds P
BC020754.1 Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9, mRNA (cDNA clone IMAGE:4766890), complete cds PA
AK289420.1 Homo sapiens cDNA FLJ75561 complete cds, highly similar to Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 (CYP2C9), mRNA PA
AK298458.1 Homo sapiens cDNA FLJ58095 complete cds, highly similar to Cytochrome P450 2C9 (EC 1.14.13.80) P
M21939.1 Human cytochrome P-450 S-mephenytoin 4-hydroxylase (P-450mp) mRNA, 3' end, clone MP-8 P
M61855.1 Human cytochrome P4502C9 (CYP2C9) mRNA, clone 25 PA
M61857.1 Human cytochrome P4502C9 (CYP2C9) mRNA, clone 65 P
S46963.1 putative CYPC2C9 gene [human, liver, mRNA, 1814 nt] PA

EST sequences (10 of 189) [Show all sequences]

BX095470.1 Clone IMAGp998P17372_;_IMAGE:195712 mixed
CB148958.1 Clone L17N670205-1-A06 liver 5' read P
CB148984.1 Clone L17N670205-1-E03 liver 5' read P
CB148999.1 Clone L17N670205-1-G09 liver 5' read P
CB154328.1 Clone L17N670205-10-B06 liver 5' read P
CB161229.1 Clone L17N670205n1-18-F12 liver 5' read P
CB161481.1 Clone L17N670205n1-34-C02 liver 5' read A
CB161916.1 Clone L17N670205n1-41-H06 liver 5' read P
CB162071.1 Clone L17N670205n1-16-H08 liver 5' read P
CB162668.1 Clone L17N670205n1-45-H01 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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