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UGID:173112     UniGene Hs.270833     Homo sapiens (human)   AREG
Amphiregulin (AREG)

Human protein-coding gene AREG. Represented by 87 ESTs from 50 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_001657.2. [UniGene 173112 - Hs.270833]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001125684.1 PREDICTED: amphiregulin H. sapiens 100.0 251
NP_033834.1 Areg gene product M. musculus 74.2 247
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001101978.1 PREDICTED: amphiregulin M. mulatta 98.4 251
XP_003898807.1 PREDICTED: amphiregulin-like P. anubis 98.4 251

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; liver; stomach; lung; intestine; skin; mixed; mammary gland; uncharacterized tissue; blood; esophagus; uterus; bone marrow; trachea; prostate; cervix; brain; lymph node; vascular; testis
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q13.3
UniSTS entry: Chr 4 SHGC-59548 [Map Viewer]
UniSTS entry: Chr 4 D4S3138 [Map Viewer]
UniSTS entry: Chr 4 SHGC-59491
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_001657.2 Homo sapiens amphiregulin (AREG), mRNA PA
M30704.1 Human amphiregulin (AR) mRNA, complete cds, clones lambda-AR1 and lambda-AR2 P
BT019866.1 Homo sapiens amphiregulin (schwannoma-derived growth factor) mRNA, complete cds P
BC009799.1 Homo sapiens amphiregulin, mRNA (cDNA clone MGC:13647 IMAGE:4277616), complete cds PA
BC146967.1 Homo sapiens amphiregulin, mRNA (cDNA clone MGC:182070 IMAGE:9056895), complete cds P
BC146953.1 Homo sapiens amphiregulin, mRNA (cDNA clone MGC:182056 IMAGE:9056881), complete cds P

EST sequences (10 of 87) [Show all sequences]

AA975933.1 Clone IMAGE:1568010 lung 3' read
CB158756.1 Clone L18POOL1n1-14-B07 liver 5' read PA
CB160040.1 Clone L18POOL1n1-47-A03 liver 5' read P
CB160087.1 Clone L18POOL1n1-47-E11 liver 5' read P
AI269804.1 Clone IMAGE:1871846 intestine 3' read A
CB127573.1 Clone C1SNU17-21-F07 cervix 5' read
CB134173.1 Clone L14ChoiCK0-16-E09 liver 5' read PA
CB134555.1 Clone L14ChoiCK0-13-A05 liver 5' read P
CB134071.1 Clone L14ChoiCK0-5-A12 liver 5' read PA
CB135707.1 Clone L14ChoiCK0-30-F12 liver 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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