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UGID:135350     UniGene Hs.27059     Homo sapiens (human)   GMPPA
GDP-mannose pyrophosphorylase A (GMPPA)

Human protein-coding gene GMPPA. Represented by 485 ESTs from 242 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 135350 - Hs.27059]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_516110.3 PREDICTED: mannose-1-phosphate guanyltransferase alpha isoform 3 P. troglodytes 100.0 419
NP_037467.2 GMPPA gene product H. sapiens 100.0 419
XP_001104343.1 PREDICTED: mannose-1-phosphate guanyltransferase alpha isoform 1 M. mulatta 99.8 419
NP_001162569.1 mannose-1-phosphate guanyltransferase alpha P. anubis 99.8 419
NP_598469.1 Gmppa gene product M. musculus 98.8 419
NP_001086043.1 mannose-1-phosphate guanyltransferase alpha-A X. laevis 79.1 420
NP_001002196.1 gmppaa gene product D. rerio 78.0 421
NP_611051.2 CG8207 D. melanogaster 64.4 437
NP_491349.1 Protein Y47D9A.1, isoform a C. elegans 55.5 397
NP_849887.1 ADP-glucose pyrophosphorylase-like protein A. thaliana 50.3 358
XP_958781.1 hypothetical protein NCU05937 N. crassa 48.8 438
Other hits (2 of 50) [Show all]SpeciesId(%)Len(aa)
NP_001020227.1 Gmppa gene product R. norvegicus 98.1 419
NP_001193104.1 mannose-1-phosphate guanyltransferase alpha B. taurus 97.6 419

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; bone marrow; uncharacterized tissue; blood; thyroid; skin; prostate; adrenal gland; placenta; embryonic tissue; lymph; lung; kidney; uterus; mammary gland; mixed; esophagus; eye; intestine; connective tissue; liver; heart; pharynx; pancreas; bone; ovary; trachea; bladder; cervix; pineal gland; larynx; parathyroid; ascites; stomach; testis; spleen; muscle; lymph node; thymus; mouth; epididymis; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q35
UniSTS entry: Chr 2 RH98301
UniSTS entry: Chr 2 A007H40 [Map Viewer]
UniSTS entry: Chr 2 stSG633042
UniSTS entry: Chr 2 REN53124
UniSTS entry: Chr 2 REN53097
UniSTS entry: Chr 2 D2S1608E
UniSTS entry: Chr 2 REN53109
UniSTS entry: Chr 2 REN53125
UniSTS entry: Chr 2 ECD23665
UniSTS entry: Chr 2 ECD09727
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_205847.2 Homo sapiens GDP-mannose pyrophosphorylase A (GMPPA), transcript variant 2, mRNA PA
AK000999.1 Homo sapiens cDNA FLJ10137 fis, clone HEMBA1003136, weakly similar to MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE (EC 2.7.7.13) P
AF135422.1 Homo sapiens GDP-mannose pyrophosphorylase A (GMPPA) mRNA, complete cds PA
AB209592.1 Homo sapiens mRNA for GDP-mannose pyrophosphorylase A variant protein P
AK222951.1 Homo sapiens mRNA for GDP-mannose pyrophosphorylase A variant, clone: HRC10067 PA
AK022578.1 Homo sapiens cDNA FLJ12516 fis, clone NT2RM2001782, highly similar to Homo sapiens GDP-mannose pyrophosphorylase A (GMPPA), transcript variant 2, mRNA P
NM_013335.3 Homo sapiens GDP-mannose pyrophosphorylase A (GMPPA), transcript variant 1, mRNA PA
BC007456.2 Homo sapiens GDP-mannose pyrophosphorylase A, mRNA (cDNA clone MGC:995 IMAGE:2989461), complete cds PA
AK290671.1 Homo sapiens cDNA FLJ78735 complete cds, highly similar to Homo sapiens GDP-mannose pyrophosphorylase A (GMPPA), transcript variant 2, mRNA PA
AK296193.1 Homo sapiens cDNA FLJ56917 complete cds, moderately similar to Homo sapiens GDP-mannose pyrophosphorylase A (GMPPA), transcript variant 2, mRNA P
BC014266.2 Homo sapiens GDP-mannose pyrophosphorylase A, mRNA (cDNA clone IMAGE:4684860), partial cds PA

EST sequences (10 of 485) [Show all sequences]

AI023862.1 Clone IMAGE:1652048 mixed 3' read A
AI041028.1 Clone IMAGE:1642564 testis 3' read PA
AI041533.1 Clone IMAGE:1643795 testis 3' read A
AI088615.1 Clone IMAGE:1696266 uterus 3' read PA
AI092342.1 Clone IMAGE:1692947 heart 3' read PA
CB053817.1 Clone IMAGE:3291033 uncharacterized tissue 5' read P
AI086630.1 Clone IMAGE:1681302 skin 3' read PA
AI160486.1 Clone IMAGE:1705360 heart 3' read A
BX114812.1 Clone IMAGp998H13780_;_IMAGE:341820 heart PA
CB152096.1 Clone B1T694954-18-C12 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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