NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:172983     UniGene Hs.270303     Homo sapiens (human)   PAX6
Paired box 6 (PAX6)

Human protein-coding gene PAX6. Represented by 254 ESTs from 86 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 172983 - Hs.270303]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001231127.1 Pax6 gene product M. musculus 100.0 435
NP_990397.1 PAX6 gene product G. gallus 100.0 435
XP_003910125.1 PREDICTED: paired box protein Pax-6 isoform 4 P. anubis 100.0 435
NP_001245391.1 PAX6 gene product H. sapiens 100.0 435
NP_001091013.1 PAX6 gene product C. lupus familiaris 100.0 435
XP_004016422.1 PREDICTED: paired box protein Pax-6 isoform 5 O. aries 100.0 435
NP_001075686.1 PAX6 gene product O. cuniculus 100.0 435
NP_037133.1 Pax6 gene product R. norvegicus 100.0 421
NP_001231101.1 paired box protein Pax-6 isoform 1 S. scrofa 100.0 421
NP_001035735.1 PAX6 gene product B. taurus 100.0 421
XP_003954413.1 PREDICTED: LOW QUALITY PROTEIN: paired box protein Pax-6 P. troglodytes 100.0 391
XP_001084865.2 PREDICTED: paired box protein Pax-6 isoform 1 M. mulatta 99.8 456
XP_003214737.1 PREDICTED: paired box protein Pax-6-like isoform 3 A. carolinensis 99.8 435
XP_001368528.2 PREDICTED: paired box protein Pax-6 isoform 1 M. domestica 99.7 552
NP_001079413.1 paired box 6 X. laevis 98.4 426
NP_571379.1 pax6a gene product D. rerio 97.0 431
NP_524638.3 twin of eyeless, isoform A D. melanogaster 69.4 516
NP_001024570.1 Protein VAB-3, isoform a C. elegans 64.8 421
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_001918200.2 PREDICTED: paired box protein Pax-6 E. caballus 99.2 394
XP_003206127.1 PREDICTED: paired box protein Pax-6-like M. gallopavo 99.2 243

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; eye; intestine; stomach; mixed; pineal gland; kidney; testis; uncharacterized tissue; lung; uterus; pituitary gland; skin; embryonic tissue; mouth; bone; muscle; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p13
UniSTS entry: Chr 11 GDB:197570
UniSTS entry: RH79881
UniSTS entry: Chr 11 GDB:316221
UniSTS entry: Chr 11 GDB:344354
UniSTS entry: RH78222
UniSTS entry: Chr 11 D12Bir2
UniSTS entry: Chr 11 Pax6
UniSTS entry: Pax6
UniSTS entry: Chr 11 RH46063
UniSTS entry: Chr 11 GDB:344736
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

M93650.1 Human paired box gene (PAX6) homologue, complete cds PA
BX640762.1 Homo sapiens mRNA; cDNA DKFZp686B14266 (from clone DKFZp686B14266) PA
NM_000280.4 Homo sapiens paired box 6 (PAX6), transcript variant 1, mRNA PA
NM_001604.5 Homo sapiens paired box 6 (PAX6), transcript variant 2, mRNA PA
AY707088.1 Homo sapiens paired box gene 6 isoform a mRNA, complete cds P
BC011953.1 Homo sapiens paired box 6, mRNA (cDNA clone MGC:17209 IMAGE:3880468), complete cds PA
AY047583.1 Homo sapiens paired box protein PAX6 (PAX6) mRNA, complete cds P
AK314470.1 Homo sapiens cDNA, FLJ95274 P
NM_001127612.1 Homo sapiens paired box 6 (PAX6), transcript variant 3, mRNA PA
AK094249.1 Homo sapiens cDNA FLJ36930 fis, clone BRACE2005251, highly similar to PAIRED BOX PROTEIN PAX-6 P
AK074881.1 Homo sapiens cDNA FLJ90400 fis, clone NT2RP2005941, highly similar to Paired box protein Pax-6 P
M77844.1 Homo sapiens oculorhombin (PAX6) mRNA, complete cds, alternatively spliced PA
GQ141695.1 Homo sapiens paired box protein 6 isoform c (PAX6) mRNA, complete cds, alternatively spliced PA
AB593094.1 Homo sapiens PAX6 mRNA for paired box protein Pax-6, complete cds, clone: HP06376-ARi61A11 PA
AB593093.1 Homo sapiens PAX6 mRNA for paired box protein Pax-6, complete cds, clone: HP06376-ARh11B12 PA
AB593092.1 Homo sapiens PAX6 mRNA for paired box protein Pax-6, complete cds, clone: HP06376-ARe92D06 PA
NM_001258465.1 Homo sapiens paired box 6 (PAX6), transcript variant 7, mRNA PA
NM_001258463.1 Homo sapiens paired box 6 (PAX6), transcript variant 5, mRNA PA
NM_001258464.1 Homo sapiens paired box 6 (PAX6), transcript variant 6, mRNA PA
NM_001258462.1 Homo sapiens paired box 6 (PAX6), transcript variant 4, mRNA PA

EST sequences (10 of 254) [Show all sequences]

R17650.1 Clone IMAGE:32366 brain 5' read
BX114225.1 Clone IMAGp998N244247_;_IMAGE:1673303 mixed
BX089704.1 Clone IMAGp998L13153_;_IMAGE:32366 brain A
AI337595.1 Clone IMAGE:1998409 brain 3' read P
AI522146.1 Clone IMAGE:2138160 kidney 3' read
R43366.1 Clone IMAGE:32366 brain 3' read A
AI652359.1 Clone IMAGE:2310081 uncharacterized tissue 3' read P
T09185.1 Clone HIBBQ26 brain 5' read P
BX281768.1 Clone IMAGp998O1410106_;_IMAGE:4400869 intestine P
AI921916.1 Clone IMAGE:2452729 uterus 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help