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UGID:172506     UniGene Hs.268785     Homo sapiens (human)   ACSL4
Acyl-CoA synthetase long-chain family member 4 (ACSL4)

Human protein-coding gene ACSL4. Represented by 388 ESTs from 188 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 172506 - Hs.268785]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_075266.1 ACSL4 gene product H. sapiens 100.0 710
XP_003317677.1 PREDICTED: long-chain-fatty-acid--CoA ligase 4 isoform 1 P. troglodytes 100.0 669
XP_001099465.1 PREDICTED: long-chain-fatty-acid--CoA ligase 4-like isoform 2 M. mulatta 99.9 710
NP_997508.1 Acsl4 gene product M. musculus 98.5 710
NP_001124420.1 acyl-CoA synthetase long-chain family member 4 X. laevis 86.9 669
NP_956943.1 acsl4a gene product D. rerio 80.6 705
NP_177882.1 long chain acyl-CoA synthetase 9 A. thaliana 56.8 687
NP_724696.1 Acyl-CoA synthetase long-chain, isoform C D. melanogaster 53.7 697
NP_508993.2 Protein ACS-17 C. elegans 53.6 698
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_003365885.1 PREDICTED: long-chain-fatty-acid--CoA ligase 4 isoform 2 E. caballus 99.4 710
XP_002720237.1 PREDICTED: acyl-CoA synthetase long-chain family member 4 O. cuniculus 99.2 710

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; testis; mouth; bone marrow; bladder; adrenal gland; kidney; uncharacterized tissue; spleen; pancreas; prostate; thyroid; larynx; trachea; liver; uterus; lung; lymph node; vascular; embryonic tissue; cervix; skin; eye; thymus; salivary gland; connective tissue; heart; mixed; blood; muscle; ovary; esophagus; adipose tissue; stomach; intestine; mammary gland; lymph; nerve; bone; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xq22.3-q23
UniSTS entry: Chr X DXS7039E
UniSTS entry: Chr X STS-N30273 [Map Viewer]
UniSTS entry: Chr X DXS6987E
UniSTS entry: Chr X ACSL4
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AF030555.1 Homo sapiens acyl-CoA synthetase 4 (ACS4) mRNA, complete cds PA
NM_004458.2 Homo sapiens acyl-CoA synthetase long-chain family member 4 (ACSL4), transcript variant 1, mRNA PA
NM_022977.2 Homo sapiens acyl-CoA synthetase long-chain family member 4 (ACSL4), transcript variant 2, mRNA PA
AK054631.1 Homo sapiens cDNA FLJ30069 fis, clone ASTRO1000096
AK292070.1 Homo sapiens cDNA FLJ78368 complete cds, highly similar to Homo sapiens acyl-CoA synthetase long-chain family member 4 (ACSL4), transcript variant 1, mRNA P
AK307566.1 Homo sapiens cDNA, FLJ97514 P
AB061714.1 Homo sapiens FACL4 mRNA for Acyl-CoA synthetase 4, complete cds, short 3'-UTR cDNA P
AB061713.1 Homo sapiens FACL4 mRNA for Acyl-CoA synthetase 4, complete cds, full-length cDNA P
AK294915.1 Homo sapiens cDNA FLJ57028 complete cds, highly similar to Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) P
Y13058.1 Homo sapiens mRNA for acyl-CoA synthetase-like protein, alternative spliced product, partial
AK294197.1 Homo sapiens cDNA FLJ52622 complete cds
BC034959.2 Homo sapiens acyl-CoA synthetase long-chain family member 4, mRNA (cDNA clone MGC:26481 IMAGE:4824121), complete cds PA
Y12777.1 Homo sapiens mRNA for acyl-CoA synthetase-like protein P

EST sequences (10 of 388) [Show all sequences]

AA921702.1 Clone IMAGE:1536909 kidney 3' read A
AI124853.1 Clone IMAGE:1539643 brain 3' read
BX092925.1 Clone IMAGp998N18186_;_IMAGE:133073 placenta
R26216.1 Clone IMAGE:133073 placenta 5' read
R26217.1 Clone IMAGE:133073 placenta 3' read A
R28548.1 Clone IMAGE:133988 placenta 5' read
R28686.1 Clone IMAGE:133988 placenta 3' read A
CB154092.1 Clone L17N670205-3-B08 liver 5' read P
CB161272.1 Clone L17N670205n1-20-D12 liver 5' read
CB159241.1 Clone L18POOL1n1-34-B12 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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