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UGID:172418     UniGene Hs.268530     Homo sapiens (human)   GPS1
G protein pathway suppressor 1 (GPS1)

Human protein-coding gene GPS1. Represented by 1126 ESTs from 373 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 172418 - Hs.268530]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003913646.1 PREDICTED: COP9 signalosome complex subunit 1 P. anubis 100.0 526
NP_997657.1 GPS1 gene product H. sapiens 100.0 526
XP_001113420.1 PREDICTED: COP9 signalosome complex subunit 1-like M. mulatta 100.0 432
NP_663345.2 Gps1 gene product M. musculus 98.7 525
NP_001084802.1 COP9 signalosome complex subunit 1 X. laevis 96.5 486
NP_001071227.1 gps1 gene product D. rerio 96.3 486
NP_524152.2 COP9 complex homolog subunit 1 b D. melanogaster 74.9 521
NP_567109.1 COP9 signalosome complex subunit 1 A. thaliana 53.9 410
XP_001702205.1 hypothetical protein CHLREDRAFT_194712 C. reinhardtii 49.1 326
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_001491682.3 PREDICTED: COP9 signalosome complex subunit 1-like isoform 2 E. caballus 98.7 477
NP_446421.3 COP9 signalosome complex subunit 1 R. norvegicus 98.7 525

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; intestine; lung; testis; placenta; mixed; uterus; adrenal gland; eye; kidney; skin; prostate; lymph; pituitary gland; spleen; cervix; bladder; mouth; blood; mammary gland; liver; thyroid; heart; pancreas; ovary; umbilical cord; connective tissue; embryonic tissue; salivary gland; stomach; muscle; lymph node; thymus; tonsil; bone; ascites; esophagus; vascular; pharynx; adipose tissue; trachea; bone marrow; larynx; ganglia; nerve; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q25.3
UniSTS entry: Chr 17 RH98836
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BT009834.1 Homo sapiens G protein pathway suppressor 1 mRNA, complete cds P
NM_004127.4 Homo sapiens G protein pathway suppressor 1 (GPS1), transcript variant 2, mRNA PA
BC064503.1 Homo sapiens G protein pathway suppressor 1, mRNA (cDNA clone MGC:71287 IMAGE:6572943), complete cds PA
NM_212492.1 Homo sapiens G protein pathway suppressor 1 (GPS1), transcript variant 1, mRNA PA
AB209596.1 Homo sapiens mRNA for G protein pathway suppressor 1 isoform 2 variant protein P
AK222508.1 Homo sapiens mRNA, G protein pathway suppressor 1 isoform 2 variant, clone: adKA03519 PA
AK026610.1 Homo sapiens cDNA: FLJ22957 fis, clone KAT09963, highly similar to HSU20285 Human Gps1 (GPS1) mRNA PA
BC000155.2 Homo sapiens G protein pathway suppressor 1, mRNA (cDNA clone MGC:5330 IMAGE:2900944), complete cds PA
AK225248.1 Homo sapiens mRNA for G protein pathway suppressor 1 isoform 2 variant, clone: DMC00580 PA
U20285.2 Human Gps1 (GPS1) mRNA, complete cds P
AK289435.1 Homo sapiens cDNA FLJ75157 complete cds, highly similar to Homo sapiens G protein pathway suppressor 1, transcript variant 1, mRNA P
AK093283.1 Homo sapiens cDNA FLJ35964 fis, clone TESTI2012592, highly similar to G PROTEIN PATHWAY SUPPRESSOR 1 P
AK297872.1 Homo sapiens cDNA FLJ55804 complete cds, highly similar to COP9 signalosome complex subunit 1 P

EST sequences (10 of 1126) [Show all sequences]

AA865730.1 Clone IMAGE:1469236 uncharacterized tissue 3' read A
AA969251.1 Clone IMAGE:1560776 mixed 3' read A
AA972517.1 Clone IMAGE:1575759 intestine 3' read P
AA974663.1 Clone IMAGE:1574459 kidney 3' read A
AA988395.1 Clone IMAGE:1593568 kidney 3' read A
AA988396.1 Clone IMAGE:1593570 kidney 3' read A
AA993663.1 Clone IMAGE:1623611 embryonic tissue 3' read A
AA994504.1 Clone IMAGE:1628886 mixed 3' read A
AA994505.1 Clone IMAGE:1628888 mixed 3' read A
AI056387.1 Clone IMAGE:1669100 brain 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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