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UGID:171602     UniGene Hs.258551     Homo sapiens (human)   DNPEP
Aspartyl aminopeptidase (DNPEP)

Human protein-coding gene DNPEP. Represented by 577 ESTs from 270 cDNA libraries. Corresponds to reference sequence NM_012100.2. [UniGene 171602 - Hs.258551]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_036232.2 DNPEP gene product H. sapiens 100.0 484
XP_001163014.2 PREDICTED: aspartyl aminopeptidase isoform 7 P. troglodytes 99.8 492
NP_001104301.1 Dnpep gene product M. musculus 92.6 474
NP_001085525.1 aspartyl aminopeptidase X. laevis 77.9 478
NP_956447.1 dnpep gene product D. rerio 76.3 468
NP_498265.1 Protein DNPP-1 C. elegans 60.0 465
NP_200824.1 aspartyl aminopeptidase A. thaliana 57.8 471
XP_957246.2 aspartyl aminopeptidase N. crassa 56.9 535
XP_001690598.1 aspartyl aminopeptidase-like protein C. reinhardtii 53.5 512
NP_011981.1 Ape4p S. cerevisiae 51.6 487
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_001103498.1 PREDICTED: aspartyl aminopeptidase isoform 7 M. mulatta 99.2 492
NP_001162487.1 aspartyl aminopeptidase P. anubis 99.2 492

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; uncharacterized tissue; testis; placenta; lung; mixed; ovary; skin; embryonic tissue; kidney; uterus; eye; blood; pancreas; vascular; spleen; liver; mammary gland; connective tissue; muscle; mouth; heart; bone; bone marrow; trachea; tonsil; lymph; ascites; prostate; cervix; thyroid; bladder; stomach; amniotic fluid; salivary gland; adrenal gland; lymph node; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q35
UniSTS entry: Chr 2 SHGC-32022 [Map Viewer]
UniSTS entry: Chr 2 SHGC-114
UniSTS entry: Chr 1 D10S275
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 1 D11S2560
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF005050.2 Homo sapiens aspartyl aminopeptidase mRNA, complete cds PA
NM_012100.2 Homo sapiens aspartyl aminopeptidase (DNPEP), mRNA P
AK001777.1 Homo sapiens cDNA FLJ10915 fis, clone OVARC1000288, weakly similar to VACUOLAR AMINOPEPTIDASE I PRECURSOR (EC 3.4.11.22) P
AK001977.1 Homo sapiens cDNA FLJ11115 fis, clone PLACE1005955, weakly similar to VACUOLAR AMINOPEPTIDASE I PRECURSOR (EC 3.4.11.22) P
AK021871.1 Homo sapiens cDNA FLJ11809 fis, clone HEMBA1006309, highly similar to Homo sapiens aspartyl aminopeptidase mRNA P
AK023005.1 Homo sapiens cDNA FLJ12943 fis, clone NT2RP2005162, highly similar to Homo sapiens aspartyl aminopeptidase mRNA P
BC003040.1 Homo sapiens aspartyl aminopeptidase, mRNA (cDNA clone IMAGE:2822867), containing frame-shift errors PA
BC000653.2 Homo sapiens aspartyl aminopeptidase, mRNA (cDNA clone MGC:899 IMAGE:3343505), complete cds PA
BC004854.2 Homo sapiens aspartyl aminopeptidase, mRNA (cDNA clone IMAGE:3926570), partial cds PA
AK302809.1 Homo sapiens cDNA FLJ58475 complete cds, highly similar to Aspartyl aminopeptidase (EC 3.4.11.21) P
AK301919.1 Homo sapiens cDNA FLJ56420 complete cds, highly similar to Aspartyl aminopeptidase (EC 3.4.11.21) P

EST sequences (10 of 577) [Show all sequences]

AA962692.1 Clone IMAGE:1575474 intestine 3' read
AA974349.1 Clone IMAGE:1586342 uncharacterized tissue 3' read PA
AA991368.1 Clone IMAGE:1608924 mammary gland 3' read
AI066726.1 Clone IMAGE:1682363 skin 3' read
AI097079.1 Clone IMAGE:1676070 embryonic tissue 3' read PA
AI128158.1 Clone IMAGE:1712350 uterus 3' read PA
AI142736.1 Clone IMAGE:1634199 mixed 3' read PA
CB052927.1 Clone IMAGE:3290414 uncharacterized tissue 5' read
BX094231.1 Clone IMAGp998I21388_;_IMAGE:201692 mixed P
AI184598.1 Clone IMAGE:1753042 testis 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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