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UGID:170498     UniGene Hs.254113     Homo sapiens (human)   POLRMT
Polymerase (RNA) mitochondrial (DNA directed) (POLRMT)

Human protein-coding gene POLRMT. Represented by 248 ESTs from 96 cDNA libraries. Corresponds to reference sequence NM_005035.3. [UniGene 170498 - Hs.254113]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005026.3 POLRMT gene product H. sapiens 100.0 1229
NP_766139.2 Polrmt gene product M. musculus 75.6 1206
NP_608565.1 mitochondrial RNA polymerase, isoform A D. melanogaster 60.6 621
NP_001080987.1 polymerase (RNA) mitochondrial (DNA directed) X. laevis 60.4 1192
XP_685138.4 PREDICTED: DNA-directed RNA polymerase, mitochondrial D. rerio 59.0 1225
NP_001190318.1 DNA-directed RNA polymerase 2 A. thaliana 51.9 428
NP_116617.1 Rpo41p S. cerevisiae 50.4 395
NP_001122531.1 Protein Y105E8A.23, isoform a C. elegans 49.2 416
XP_962570.2 hypothetical protein NCU06308 N. crassa 47.2 182
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
XP_003316023.1 PREDICTED: DNA-directed RNA polymerase, mitochondrial P. troglodytes 96.2 1255
XP_003914585.1 PREDICTED: DNA-directed RNA polymerase, mitochondrial P. anubis 91.1 1225

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; embryonic tissue; eye; uncharacterized tissue; kidney; liver; prostate; ovary; placenta; mixed; lung; mammary gland; cervix; uterus; intestine; bone; lymph; heart; pancreas; muscle; stomach; ascites; connective tissue; spleen; lymph node; parathyroid; thyroid
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_005035.3 Homo sapiens polymerase (RNA) mitochondrial (DNA directed) (POLRMT), nuclear gene encoding mitochondrial protein, mRNA P
BC070057.1 Homo sapiens cDNA clone IMAGE:5296766, containing frame-shift errors PA
AB209920.1 Homo sapiens mRNA for DNA-directed RNA polymerase variant protein P
BC098387.1 Homo sapiens polymerase (RNA) mitochondrial (DNA directed), mRNA (cDNA clone MGC:104585 IMAGE:5264127), complete cds PA
AK225865.1 Homo sapiens mRNA for mitochondrial DNA-directed RNA polymerase precursor variant, clone: FCC124G05 PA
AK225723.1 Homo sapiens mRNA for mitochondrial DNA-directed RNA polymerase precursor variant, clone: TST02840 PA
AK307525.1 Homo sapiens cDNA, FLJ97473 P
AK302877.1 Homo sapiens cDNA FLJ58806 complete cds, highly similar to DNA-directed RNA polymerase, mitochondrial precursor (EC PA
BC030829.1 Homo sapiens cDNA clone IMAGE:4799009 PA
BC024170.2 Homo sapiens polymerase (RNA) mitochondrial (DNA directed), mRNA (cDNA clone IMAGE:2820301) PA
U75370.1 Human mitochondrial RNA polymerase mRNA, nuclear gene encoding mitochondrial protein, complete cds PA

EST sequences (10 of 248) [Show all sequences]

AI023790.1 Clone IMAGE:1655730 mixed 3' read PA
BX107393.1 Clone IMAGp998B17837_;_IMAGE:363568 eye A
R31115.1 Clone IMAGE:134269 placenta 3' read A
AI279683.1 Clone IMAGE:1891536 placenta 3' read P
AI284331.1 Clone IMAGE:1864343 kidney 3' read P
AI287533.1 Clone IMAGE:1891570 placenta 3' read P
AI394276.1 Clone IMAGE:2108280 uncharacterized tissue 3' read P
AI473314.1 Clone IMAGE:2125265 mixed 3' read P
AI539005.1 Clone IMAGE:2204728 uterus 3' read PA
AI633080.1 Clone IMAGE:2287358 uterus 3' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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