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UGID:170095     UniGene Hs.253197     Homo sapiens (human)   PARN
Poly(A)-specific ribonuclease (PARN)

Human protein-coding gene PARN. Represented by 334 ESTs from 193 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 170095 - Hs.253197]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_510832.3 PREDICTED: poly(A)-specific ribonuclease PARN isoform 3 P. troglodytes 100.0 638
NP_002573.1 PARN gene product H. sapiens 100.0 638
XP_003916630.1 PREDICTED: poly(A)-specific ribonuclease PARN P. anubis 99.5 620
NP_083037.1 poly(A)-specific ribonuclease PARN M. musculus 93.1 623
NP_001081143.1 poly(A)-specific ribonuclease PARN X. laevis 85.3 630
NP_957382.1 parn gene product D. rerio 79.0 646
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_002808334.1 PREDICTED: LOW QUALITY PROTEIN: poly(A)-specific ribonuclease PARN-like M. mulatta 99.2 595
NP_001094588.1 PARN gene product B. taurus 98.3 637

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; vascular; lymph node; ovary; prostate; pharynx; uncharacterized tissue; mixed; kidney; connective tissue; eye; uterus; skin; intestine; mouth; muscle; adrenal gland; bladder; tonsil; blood; bone marrow; nerve; thymus; placenta; liver; lung; thyroid; mammary gland; esophagus; lymph; spleen; ascites; bone; pancreas; larynx; trachea; stomach; heart; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13
UniSTS entry: Chr 16 SHGC-64760
UniSTS entry: Chr 16 RH69315
UniSTS entry: Chr 16 D15S543
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BC044763.1 Homo sapiens poly(A)-specific ribonuclease (deadenylation nuclease), mRNA (cDNA clone IMAGE:4826198) PA
AJ005698.1 Homo sapiens mRNA for poly(A)-specific ribonuclease P
BC050029.1 Homo sapiens poly(A)-specific ribonuclease (deadenylation nuclease), mRNA (cDNA clone MGC:41881 IMAGE:4825218), complete cds PA
NM_002582.3 Homo sapiens poly(A)-specific ribonuclease (PARN), transcript variant 1, mRNA P
AK023866.1 Homo sapiens cDNA FLJ13804 fis, clone THYRO1000197, highly similar to Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) P
AK315020.1 Homo sapiens cDNA, FLJ95954, Homo sapiens poly(A)-specific ribonuclease (deadenylation nuclease)(PARN), mRNA P
AK301648.1 Homo sapiens cDNA FLJ57636 complete cds, highly similar to Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) P
AK293189.1 Homo sapiens cDNA FLJ58764 complete cds, highly similar to Poly(A)-specific ribonuclease PARN (EC3.1.13.4) P
AK299653.1 Homo sapiens cDNA FLJ58618 complete cds, highly similar to Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) P
AK303348.1 Homo sapiens cDNA FLJ57461 complete cds, highly similar to Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) P
NM_001134477.2 Homo sapiens poly(A)-specific ribonuclease (PARN), transcript variant 2, mRNA P
NM_001242992.1 Homo sapiens poly(A)-specific ribonuclease (PARN), transcript variant 3, mRNA P

EST sequences (10 of 334) [Show all sequences]

AI097558.1 Clone IMAGE:1685812 brain 3' read A
BX113575.1 Clone IMAGp998F11736_;_IMAGE:324874 skin
AI192142.1 Clone IMAGE:1721657 uterus 3' read
AI208459.1 Clone IMAGE:1837263 testis 3' read
CB135550.1 Clone L14ChoiCK0-31-E11 liver 5' read
CB143265.1 Clone L15CKK1-34-H03 liver 5' read P
AI308996.1 Clone IMAGE:1915752 kidney 3' read
AI309002.1 Clone IMAGE:1915768 kidney 3' read A
AI364427.1 Clone IMAGE:1993321 uterus 3' read
AI634785.1 Clone IMAGE:2295568 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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