NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:169739     UniGene Hs.250712     Homo sapiens (human)   CACNB3
Calcium channel, voltage-dependent, beta 3 subunit (CACNB3)

Human protein-coding gene CACNB3. Represented by 275 ESTs from 151 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 169739 - Hs.250712]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_509034.3 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform 2 P. troglodytes 100.0 483
NP_000716.2 CACNB3 gene product H. sapiens 100.0 483
XP_543689.3 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform 2 C. lupus familiaris 100.0 483
XP_001504155.2 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform 1 E. caballus 100.0 482
NP_031607.2 voltage-dependent L-type calcium channel subunit beta-3 isoform 1 M. musculus 99.8 483
NP_036960.1 Cacnb3 gene product R. norvegicus 99.8 483
XP_001103098.1 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform 3 M. mulatta 99.8 483
XP_003906348.1 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform 1 P. anubis 99.8 483
XP_003481614.1 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 S. scrofa 99.6 490
NP_776934.1 CACNB3 gene product B. taurus 99.6 483
XP_004006441.1 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform 1 O. aries 99.6 483
NP_001079266.1 calcium channel, voltage-dependent, beta 3 subunit X. laevis 89.3 483
NP_001035408.2 cacnb4b gene product D. rerio 79.8 488
NP_523546.1 Ca2+-channel-protein-beta-subunit, isoform E D. melanogaster 72.6 424
NP_491193.2 Protein CCB-1 C. elegans 66.7 498
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
NP_001095185.1 voltage-dependent L-type calcium channel subunit beta-3 O. cuniculus 99.4 476
XP_001364465.1 PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform 1 M. domestica 97.7 481

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; mammary gland; pituitary gland; embryonic tissue; uterus; intestine; stomach; eye; lung; kidney; testis; mixed; pancreas; prostate; skin; mouth; esophagus; umbilical cord; nerve; thymus; ovary; placenta; connective tissue; blood; liver; lymph node; ascites; muscle; heart; bone; vascular; bone marrow; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13
UniSTS entry: Chr 12 IB1472 [Map Viewer]
UniSTS entry: Chr 12 D12S2032 [Map Viewer]
UniSTS entry: Chr 12 WI-18779 [Map Viewer]
UniSTS entry: Chr 12 CACNB3_499
UniSTS entry: RH11169
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_000725.3 Homo sapiens calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1, mRNA PA
L27584.1 Homo sapiens Ca channel B3 subunit gene, complete cds P
U07139.1 Human voltage-gated calcium channel beta subunit mRNA, complete cds P
AK289709.1 Homo sapiens cDNA FLJ75579 complete cds, highly similar to Homo sapiens calcium channel, voltage-dependent, beta 3 subunit (CACNB3), mRNA P
X76555.1 H.sapiens CAB3a mRNA for calcium channel beta3 subunit P
X76556.1 H.sapiens CAB3b mRNA for calcium channel beta3 subunit P
AK074551.1 Homo sapiens cDNA FLJ90070 fis, clone HEMBA1004007
AK316323.1 Homo sapiens cDNA, FLJ79222 complete cds, highly similar to Voltage-dependent L-type calcium channel subunit beta-3 P
AK304537.1 Homo sapiens cDNA FLJ58411 complete cds, highly similar to Voltage-dependent L-type calcium channel subunit beta-3 P
AK297639.1 Homo sapiens cDNA FLJ57401 complete cds, highly similar to Voltage-dependent L-type calcium channel subunit beta-3 P
NM_001206917.1 Homo sapiens calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 4, mRNA PA
NM_001206916.1 Homo sapiens calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 3, mRNA PA
NM_001206915.1 Homo sapiens calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 2, mRNA PA
BC041811.1 Homo sapiens calcium channel, voltage-dependent, beta 3 subunit, mRNA (cDNA clone MGC:41895 IMAGE:5315091), complete cds PA

EST sequences (10 of 275) [Show all sequences]

AA947814.1 Clone IMAGE:1374955 ovary A
AA962067.1 Clone IMAGE:1592609 kidney 3' read A
T05783.1 Clone HFBDG35 brain
AA928344.1 Clone IMAGE:1559988 intestine 3' read A
T06059.1 Clone HFBDN67 brain
R20849.1 Clone IMAGE:31239 brain 5' read
AI086918.1 Clone IMAGE:1680706 skin 3' read
AI214829.1 Clone IMAGE:1840051 testis 3' read A
AI251769.1 Clone IMAGE:1978010 brain 3' read A
CB156070.1 Clone L18POOL1n1-1-C03 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help