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UGID:168360     UniGene Hs.244139     Homo sapiens (human)   FAS
Fas (TNF receptor superfamily, member 6) (FAS)

Human protein-coding gene FAS. Represented by 200 ESTs from 112 cDNA libraries. Corresponds to 8 reference sequences (different isoforms). [UniGene 168360 - Hs.244139]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000034.1 FAS gene product H. sapiens 100.0 334
NP_032013.2 Fas gene product M. musculus 54.6 326
Other hits (2 of 10) [Show all]SpeciesId(%)Len(aa)
XP_003312790.1 PREDICTED: uncharacterized protein LOC738331 P. troglodytes 99.5 361
XP_003904018.1 PREDICTED: tumor necrosis factor receptor superfamily member 6 isoform 1 P. anubis 89.7 330

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: eye; brain; blood; mixed; uncharacterized tissue; adipose tissue; lung; placenta; muscle; uterus; kidney; lymph node; vascular; pharynx; skin; prostate; pancreas; bladder; adrenal gland; connective tissue; heart; intestine; testis; spleen; mouth; thymus; liver; trachea; cervix; lymph; stomach; ovary; mammary gland; bone marrow; bone; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24.1
UniSTS entry: Chr 10 RH91808
UniSTS entry: Chr 10 PMC96480P1
UniSTS entry: Chr 10 RH11007 [Map Viewer]
UniSTS entry: GDB:362780
UniSTS entry: GDB:362783
UniSTS entry: Chr 10 D10S2281
UniSTS entry: GDB:362785
UniSTS entry: GDB:682143
UniSTS entry: Chr 10 SHGC-30908 [Map Viewer]
UniSTS entry: GDB:681362
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (36)

NM_000043.4 Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 1, mRNA PA
CR450307.1 Homo sapiens full open reading frame cDNA clone RZPDo834E051D for gene TNFRSF6, tumor necrosis factor receptor superfamily, member 6; complete cds; without stopcodon P
AB209361.1 Homo sapiens mRNA for tumor necrosis factor receptor superfamily, member 6 isoform 1 precursor variant protein P
M67454.1 Human Fas antigen (fas) mRNA, complete cds P
BC012479.1 Homo sapiens Fas (TNF receptor superfamily, member 6), mRNA (cDNA clone MGC:21432 IMAGE:4514272), complete cds PA
Z47993.1 H.sapiens FASTM Del mRNA P
Z47994.1 H.sapiens FAS Del 2 mRNA P
Z47995.1 H.sapiens FAS Del3 mRNA P
AK290978.1 Homo sapiens cDNA FLJ77106 complete cds, highly similar to Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 1, mRNA P
Z70520.1 H.sapiens FAS/Apo 1 mRNA for FAS soluble protein (clone FAS Exo4,6Del) P
Z70519.1 H.sapiens FAS/Apo 1 mRNA for FAS soluble protein (clone FAS Exo4Del) P
AY495076.1 Homo sapiens Fas AMA mRNA, complete cds P
AK311499.1 Homo sapiens cDNA, FLJ18541 P
AK311424.1 Homo sapiens cDNA, FLJ18466 P
AK311164.1 Homo sapiens cDNA, FLJ18206 P
X63717.1 H.sapiens mRNA for APO-1 cell surface antigen P
FM246459.1 Homo sapiens mRNA for truncated tumor necrosis factor receptor superfamily member 6 protein (TNFRSF6 gene), patient JBB P
FM246458.1 Homo sapiens mRNA for tumor necrosis factor receptor superfamily member 6 (TNFRSF6 gene), patient MRR P
FM246457.1 Homo sapiens TNFRSF6 pseudogene mRNA, patient BHR P
Z66556.1 H.sapiens FASExo8Del mRNA P
X83492.1 H.sapiens mRNA for Fas/Apo-1 (clone pCRTM11-Fasdelta(4,7)) P
X83491.1 H.sapiens mRNA for Fas/Apo-1 (clone pCRTM11-Fasdelta(3,4,6)) P
X83490.1 H.sapiens mRNA for Fas/Apo-1 (clone pCRTM11-Fasdelta(3,4)) P
X83493.1 H.sapiens mRNA for Fas/Apo-1 (clone pCRTM11-FasdeltaTM) P
FJ373046.1 Homo sapiens FAS variant (FAS) mRNA, complete cds P
FJ373045.1 Homo sapiens FAS variant (FAS) mRNA, complete cds P
EU481974.1 Homo sapiens FAS 827dupA variant (FAS) mRNA, complete cds P
X89101.1 H.sapiens mRNA for Fas (Apo-1, CD95) P
NM_152872.2 Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 3, mRNA PA
NM_152871.2 Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 2, mRNA PA
NR_028036.2 Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 7, non-coding RNA PA
NR_028034.2 Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 5, non-coding RNA PA
NR_028035.2 Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 6, non-coding RNA PA
NR_028033.2 Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 4, non-coding RNA PA
NR_028371.1 Homo sapiens FAS antisense RNA 1 (FAS-AS1), non-coding RNA A
FJ200481.1 Homo sapiens FAS receptor variant 9 mRNA, complete cds

EST sequences (10 of 200) [Show all sequences]

AA903256.1 Clone IMAGE:1517281 uncharacterized tissue 3' read A
AI082029.1 Clone IMAGE:1678610 mixed 3' read A
BX113824.1 Clone IMAGp998G141855_;_IMAGE:754597 mixed
CB158553.1 Clone L18POOL1n1-11-F02 liver 5' read P
CB135078.1 Clone L14ChoiCK0-19-D11 liver 5' read
AI278441.1 Clone IMAGE:1892470 placenta 3' read A
AI309268.1 Clone IMAGE:1914173 kidney 3' read
AI333110.1 Clone IMAGE:1933701 mixed 3' read A
AI337873.1 Clone IMAGE:1949870 uterus 3' read A
AI422313.1 Clone IMAGE:2104676 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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