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UGID:167438     UniGene Hs.235069     Homo sapiens (human)   RECQL
RecQ protein-like (DNA helicase Q1-like) (RECQL)

Human protein-coding gene RECQL. Represented by 317 ESTs from 164 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 167438 - Hs.235069]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_520788.3 PREDICTED: ATP-dependent DNA helicase Q1 P. troglodytes 100.0 648
NP_116559.1 RECQL gene product H. sapiens 100.0 648
XP_002798535.1 PREDICTED: ATP-dependent DNA helicase Q1 isoform 2 M. mulatta 99.5 648
NP_075529.2 Recql gene product M. musculus 90.6 647
NP_001089858.1 RecQ protein-like (DNA helicase Q1-like) X. laevis 80.8 641
NP_001038561.2 recql gene product D. rerio 66.8 636
XP_001690973.1 hypothetical protein CHLREDRAFT_128016 C. reinhardtii 55.0 484
NP_001022657.1 Protein K02F3.12, isoform b C. elegans 54.0 592
NP_001077639.1 ATP-dependent DNA helicase Q-like 2 A. thaliana 53.3 452
XP_964030.2 hypothetical protein NCU08598 N. crassa 49.9 421
NP_524319.2 bloom syndrome helicase ortholog D. melanogaster 49.4 356
NP_013915.1 Sgs1p S. cerevisiae 48.7 413
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_003906142.1 PREDICTED: ATP-dependent DNA helicase Q1 P. anubis 99.4 648
NP_001071459.1 RECQL gene product B. taurus 94.6 648

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mouth; testis; lung; skin; intestine; adrenal gland; placenta; eye; thyroid; pharynx; bladder; vascular; uncharacterized tissue; blood; connective tissue; lymph node; trachea; embryonic tissue; ovary; kidney; pancreas; thymus; uterus; mixed; heart; liver; muscle; prostate; stomach; bone marrow; spleen; cervix; lymph; mammary gland; ascites; bone; nerve; ear
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p12
UniSTS entry: Chr 11 RH39888
UniSTS entry: Chr 11 RH79569
UniSTS entry: Chr 12 RH102863
UniSTS entry: Chr 11 RH80431
UniSTS entry: Chr 11 RH68343
UniSTS entry: Chr 11 G62019
UniSTS entry: Chr 12 RH39709
UniSTS entry: Chr 12 GDB:581119
UniSTS entry: Chr 11 RH93629
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AY157499.1 Homo sapiens truncated helicase isoform (RECQL) mRNA, complete cds PA
BT007119.1 Homo sapiens RecQ protein-like (DNA helicase Q1-like) mRNA, complete cds P
NM_002907.3 Homo sapiens RecQ protein-like (DNA helicase Q1-like) (RECQL), transcript variant 1, mRNA PA
D37984.1 Homo sapiens mRNA for DNA helicase Q1, partial cds P
L36140.1 Homo sapiens (clone 1311) DNA helicase (RECQL) mRNA, complete cds PA
BC001052.2 Homo sapiens RecQ protein-like (DNA helicase Q1-like), mRNA (cDNA clone MGC:1648 IMAGE:2823112), complete cds PA
NM_032941.2 Homo sapiens RecQ protein-like (DNA helicase Q1-like) (RECQL), transcript variant 2, mRNA PA
AK291627.1 Homo sapiens cDNA FLJ76305 complete cds, highly similar to Homo sapiens RecQ protein-like (DNA helicase Q1-like) (RECQL), transcript variant 1, mRNA P

EST sequences (10 of 317) [Show all sequences]

AA969326.1 Clone IMAGE:1580477 mixed 3' read A
AA948182.1 Clone IMAGE:1588143 uncharacterized tissue 3' read A
AI089200.1 Clone IMAGE:1634630 mixed 3' read A
AI090785.1 Clone IMAGE:1691684 heart 3' read A
AI138659.1 Clone IMAGE:1709903 heart 3' read A
BX093234.1 Clone IMAGp998C221964_;_IMAGE:796365 embryonic tissue
CB158017.1 Clone L18POOL1n1-7-A11 liver 5' read P
AI350978.1 Clone IMAGE:1934578 embryonic tissue 3' read A
AI474213.1 Clone IMAGE:2115407 mixed 3' read A
AI628807.1 Clone IMAGE:2284656 kidney 3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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