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UGID:134240     UniGene Hs.21374     Homo sapiens (human)   SNCA
Synuclein, alpha (non A4 component of amyloid precursor) (SNCA)

Human protein-coding gene SNCA. Represented by 292 ESTs from 102 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 134240 - Hs.21374]

SELECTED PROTEIN SIMILARITIES
GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; connective tissue; mixed; heart; lung; uncharacterized tissue; skin; pancreas; intestine; ear; ovary; testis; uterus; prostate; placenta; blood; embryonic tissue; eye; mammary gland; liver; bladder; nerve; vascular; bone; kidney; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q21
UniSTS entry: Chr 4 GDB:593720
UniSTS entry: Chr 4 D4S3159 [Map Viewer]
UniSTS entry: Chr 4 D4S3299
UniSTS entry: Chr 4 SHGC-50183
UniSTS entry: Chr 4 GDB:593735
UniSTS entry: Chr 4 SNCA_s25
UniSTS entry: Chr 4 SHGC-67637 [Map Viewer]
UniSTS entry: Chr 4 RH102522
UniSTS entry: Chr 4 D4S2505E [Map Viewer]
UniSTS entry: PMC153617P2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

NM_000345.3 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1, mRNA PA
NM_007308.2 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 4, mRNA PA
CR457058.1 Homo sapiens full open reading frame cDNA clone RZPDo834A087D for gene SNCA, synuclein, alpha (non A4 component of amyloid precursor); complete cds, incl. stopcodon P
CR541653.1 Homo sapiens full open reading frame cDNA clone RZPDo834A0827D for gene SNCA, synuclein, alpha (non A4 component of amyloid precursor); complete cds, without stopcodon P
BC108275.1 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor), mRNA (cDNA clone MGC:110988 IMAGE:6147966), complete cds PA
L08850.1 Human AD amyloid mRNA, complete cds P
L36674.1 Human (clone 2-5) synuclein (NACP) mRNA, complete cds P
L36675.1 Human (clone 2-4) synuclein (NACP) mRNA, complete cds P
BC013293.2 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor), mRNA (cDNA clone MGC:3484 IMAGE:3604532), complete cds PA
AY049786.1 Homo sapiens synuclein alpha (SNCA) mRNA, complete cds P
AK290169.1 Homo sapiens cDNA FLJ76529 complete cds, highly similar to Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant NACP140, mRNA P
D31839.1 Homo sapiens alternatively spliced mRNA for NACP (precursor of non-A beta component of Alzheimer's disease amyloid), complete cds P
NM_001146055.1 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 3, mRNA PA
NM_001146054.1 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 2, mRNA PA
HQ830269.1 Homo sapiens clone asynex1`` synuclein alpha-140 (NACP) mRNA, 5' UTR and partial cds, alternatively spliced P
HQ830268.1 Homo sapiens clone asynex1` synuclein alpha-140 (NACP) mRNA, 5' UTR and partial cds, alternatively spliced P
HQ830267.1 Homo sapiens clone asynex1 synuclein alpha-140 (NACP) mRNA, 5' UTR and partial cds, alternatively spliced P

EST sequences (10 of 292) [Show all sequences]

R16018.1 Clone IMAGE:66473 mixed 5' read
AI033292.1 Clone IMAGE:1652561 mixed 3' read A
AI052682.1 Clone IMAGE:1676438 embryonic tissue 3' read A
R20629.1 Clone IMAGE:26298 brain 3' read A
AI147286.1 Clone IMAGE:1703074 brain 3' read
AI160944.1 Clone IMAGE:1704958 heart 3' read A
BX101850.1 Clone IMAGp998M14139_;_IMAGE:26298 brain A
AI269192.1 Clone IMAGE:1857527 mixed 3' read A
R31354.1 Clone IMAGE:135534 placenta 5' read
AA911019.1 Clone IMAGE:1518456 uncharacterized tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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