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UGID:164647     UniGene Hs.212774     Homo sapiens (human)   UBA6
Ubiquitin-like modifier activating enzyme 6 (UBA6)

Human protein-coding gene UBA6. Represented by 262 ESTs from 142 cDNA libraries. Corresponds to reference sequence NM_018227.5. [UniGene 164647 - Hs.212774]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_060697.4 UBA6 gene product H. sapiens 100.0 1051
XP_001164227.2 PREDICTED: ubiquitin-like modifier activating enzyme 6 P. troglodytes 99.9 1051
NP_766300.1 Uba6 gene product M. musculus 92.2 1052
XP_695755.3 PREDICTED: ubiquitin-like modifier-activating enzyme 6-like D. rerio 72.8 1029
NP_477310.2 ubiquitin activating enzyme 1, isoform A D. melanogaster 53.8 379
NP_001033405.1 Protein UBA-1, isoform b C. elegans 53.0 328
NP_568168.1 ubiquitin-activating enzyme E1 2 A. thaliana 52.9 255
NP_012712.1 E1 ubiquitin-activating protein UBA1 S. cerevisiae 51.7 736
NP_001128500.1 ubiquitin-like modifier activating enzyme 1 X. laevis 51.5 982
XP_956143.1 ubiquitin-activating enzyme E1 1 N. crassa 50.7 641
XP_001695180.1 ubiquitin-activating enzyme E1 C. reinhardtii 49.4 261
Other hits (2 of 59) [Show all]SpeciesId(%)Len(aa)
XP_003898886.1 PREDICTED: ubiquitin-like modifier-activating enzyme 6 P. anubis 99.2 1009
XP_002804149.1 PREDICTED: ubiquitin-like modifier-activating enzyme 6-like M. mulatta 99.0 1053

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; embryonic tissue; lung; pancreas; uterus; lymph node; placenta; eye; intestine; bladder; bone marrow; testis; mixed; mouth; kidney; skin; muscle; ovary; stomach; cervix; mammary gland; liver; spleen; trachea; thymus; prostate; thyroid; pharynx; blood; salivary gland; connective tissue; larynx; spinal cord; ear; nerve; heart; bone; ganglia; adrenal gland
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q13.2
UniSTS entry: Chr 4 SHGC-52778 [Map Viewer]
UniSTS entry: Chr 4 RH93660
UniSTS entry: Chr 4 RH98488
UniSTS entry: Chr 4 D4S2752
UniSTS entry: Chr 2 ha3312
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AY359880.1 Homo sapiens hypothetical protein FLJ10808 isoform mRNA, complete cds PA
AK126301.1 Homo sapiens cDNA FLJ44322 fis, clone TRACH3001550
AK001670.1 Homo sapiens cDNA FLJ10808 fis, clone NT2RP4000879, weakly similar to UBIQUITIN-ACTIVATING ENZYME E1 P
NM_018227.5 Homo sapiens ubiquitin-like modifier activating enzyme 6 (UBA6), mRNA PA
AK027020.1 Homo sapiens cDNA: FLJ23367 fis, clone HEP15725 PA
AB014773.1 Homo sapiens mRNA for MOP-4, complete cds P
BC126486.1 Homo sapiens ubiquitin-like modifier activating enzyme 6, mRNA (cDNA clone MGC:161764 IMAGE:8992202), complete cds P
BC126484.1 Homo sapiens ubiquitin-like modifier activating enzyme 6, mRNA (cDNA clone MGC:161762 IMAGE:8992200), complete cds P
EF623993.1 Homo sapiens ubiquitin-activating enzyme 6 mRNA, complete cds P
AK314371.1 Homo sapiens cDNA, FLJ95140 P
BC031637.1 Homo sapiens ubiquitin-like modifier activating enzyme 6, mRNA (cDNA clone IMAGE:5172175), complete cds PA
AK094969.1 Homo sapiens cDNA FLJ37650 fis, clone BRHIP2000553, weakly similar to UBIQUITIN-ACTIVATING ENZYME E1 1 P
AK094164.1 Homo sapiens cDNA FLJ36845 fis, clone ASTRO2013050, weakly similar to UBIQUITIN-ACTIVATING ENZYME E1 P
AL832458.2 Homo sapiens mRNA; cDNA DKFZp451P021 (from clone DKFZp451P021); complete cds PA
AL832015.2 Homo sapiens mRNA; cDNA DKFZp451F154 (from clone DKFZp451F154); complete cds PA

EST sequences (10 of 262) [Show all sequences]

AA978308.1 Clone IMAGE:1568030 lung 3' read
AI005202.1 Clone IMAGE:1632210 mammary gland 3' read A
AI039310.1 Clone IMAGE:1658377 embryonic tissue 3' read
AI142670.1 Clone IMAGE:1509660 mixed 3' read
BX103988.1 Clone IMAGp998M151898_;_IMAGE:771254 ovary A
AI262109.1 Clone IMAGE:2028700 kidney 3' read
CB150657.1 Clone C1SNU17-32-F12 cervix 5' read
AI334711.1 Clone IMAGE:1998363 brain 3' read A
AI342190.1 Clone IMAGE:1950238 lung 3' read
AI374617.1 Clone IMAGE:2047929 embryonic tissue 3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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