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UGID:134203     UniGene Hs.21213     Homo sapiens (human)   MYO5A
Myosin VA (heavy chain 12, myoxin) (MYO5A)

Human protein-coding gene MYO5A. Represented by 369 ESTs from 168 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 134203 - Hs.21213]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_510412.2 PREDICTED: unconventional myosin-Va isoform 7 P. troglodytes 100.0 1854
NP_000250.3 MYO5A gene product H. sapiens 100.0 1854
XP_003901000.1 PREDICTED: unconventional myosin-Va isoform 2 P. anubis 99.6 1854
NP_034994.2 Myo5a gene product M. musculus 98.6 1852
NP_001080717.1 myosin VA X. laevis 93.7 585
NP_001074428.1 myosin-Va D. rerio 87.6 1843
NP_724570.1 dilute class unconventional myosin, isoform B D. melanogaster 59.7 1164
NP_505433.3 Protein HUM-2, isoform a C. elegans 54.3 1059
NP_009373.1 myosin 4 S. cerevisiae 54.1 808
NP_175453.2 P-loop containing nucleoside triphosphate hydrolase-like protein A. thaliana 53.4 515
XP_001728528.1 hypothetical protein NCU11354 N. crassa 52.6 852
XP_001696752.1 hypothetical protein CHLREDRAFT_119317 C. reinhardtii 49.0 479
Other hits (2 of 58) [Show all]SpeciesId(%)Len(aa)
XP_001084476.1 PREDICTED: myosin-Va M. mulatta 99.3 1834
XP_001926803.4 PREDICTED: myosin-Va S. scrofa 99.1 1854

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; uncharacterized tissue; mixed; uterus; intestine; thyroid; pharynx; blood; eye; kidney; stomach; mammary gland; embryonic tissue; lung; lymph node; pancreas; prostate; vascular; muscle; testis; nerve; liver; mouth; connective tissue; spleen; thymus; bladder; epididymis; bone marrow; salivary gland; heart; adrenal gland; bone; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q21
UniSTS entry: Chr 15 WI-12413 [Map Viewer]
UniSTS entry: Chr 15 A004G21
UniSTS entry: Chr 15 RH66379 [Map Viewer]
UniSTS entry: Chr 15 WI-19762 [Map Viewer]
UniSTS entry: Chr 15 RH69927
UniSTS entry: Chr 15 MYO5A
UniSTS entry: Chr 15 STS-R41828
UniSTS entry: MARC_17607-17608:1018452356:1
UniSTS entry: Chr 15 AB060208
UniSTS entry: Chr 15 RH103873
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

U90942.1 Human myosin heavy chain 12 (MYO5A) mRNA, complete cds P
AK124898.1 Homo sapiens cDNA FLJ42908 fis, clone BRHIP3018797 A
AB209505.1 Homo sapiens mRNA for Myosin Va variant protein P
AB209487.1 Homo sapiens mRNA for Myosin Va variant protein P
NM_000259.3 Homo sapiens myosin VA (heavy chain 12, myoxin) (MYO5A), transcript variant 1, mRNA PA
AK057146.1 Homo sapiens cDNA FLJ32584 fis, clone SPLEN2000350
AB290180.1 Homo sapiens mRNA for MYO5A variant protein, complete cds PA
AK307600.1 Homo sapiens cDNA, FLJ97548 P
AK090859.1 Homo sapiens cDNA FLJ33540 fis, clone BRAMY2007613 A
AK303660.1 Homo sapiens cDNA FLJ50342 partial cds, highly similar to Myosin-5A P
EU921839.1 Homo sapiens myosin Va mRNA, exons A, C, E, and partial cds, alternatively spliced P
AF055459.1 Homo sapiens myosin Va (MYR12) mRNA, alternatively spliced, partial cds P
AF090428.1 Homo sapiens alternatively spliced myosin V mRNA, partial cds P
AF090427.1 Homo sapiens alternatively spliced myosin V mRNA, partial cds P
AF090426.1 Homo sapiens alternatively spliced myosin V mRNA, partial cds P
AF090425.1 Homo sapiens alternatively spliced myosin V mRNA, partial cds P
AF090424.1 Homo sapiens alternatively spliced myosin V mRNA, partial cds P
S74799.1 MYH12=myosin heavy chain 12 [human, brain, mRNA Partial, 1235 nt] P
NM_001142495.1 Homo sapiens myosin VA (heavy chain 12, myoxin) (MYO5A), transcript variant 2, mRNA PA
Y07759.1 H.sapiens mRNA for myosin heavy chain 12 P

EST sequences (10 of 369) [Show all sequences]

AA902442.1 Clone IMAGE:1521281 lung 3' read A
AI094198.1 Clone IMAGE:1688181 mixed 3' read A
T06241.1 Clone HFBDQ75 brain
BX094384.1 Clone IMAGp998N24648 skin 5' read
BX104390.1 Clone IMAGp998K19649_;_IMAGE:291594 skin
BX104592.1 Clone IMAGp998I16328_;_IMAGE:178647 brain A
BX115258.1 Clone IMAGp998F155716_;_IMAGE:2306702 uncharacterized tissue
BX089798.1 Clone IMAGp998D24582_;_IMAGE:265703 skin P
AI266419.1 Clone IMAGE:1899764 kidney 3' read
CB137614.1 Clone L5HLK1-35-G07 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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