NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:164369     UniGene Hs.211594     Homo sapiens (human)   PSMC4
Proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4)

Human protein-coding gene PSMC4. Represented by 948 ESTs from 308 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 164369 - Hs.211594]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_036004.2 Psmc4 gene product M. musculus 100.0 417
NP_476463.1 Psmc4 gene product R. norvegicus 100.0 417
XP_003341107.1 PREDICTED: 26S protease regulatory subunit 6B-like isoform 1 M. domestica 100.0 417
XP_001090787.1 PREDICTED: 26S protease regulatory subunit 6B isoform 4 M. mulatta 100.0 417
XP_003915578.1 PREDICTED: 26S protease regulatory subunit 6B isoform 1 P. anubis 100.0 417
XP_001141307.1 PREDICTED: 26S protease regulatory subunit 6B isoform 5 P. troglodytes 100.0 417
NP_006494.1 PSMC4 gene product H. sapiens 100.0 417
XP_003638879.1 PREDICTED: 26S protease regulatory subunit 6B-like C. lupus familiaris 100.0 417
XP_001498459.1 PREDICTED: 26S protease regulatory subunit 6B isoform 1 E. caballus 100.0 417
NP_001030255.1 PSMC4 gene product B. taurus 100.0 417
XP_004015299.1 PREDICTED: 26S protease regulatory subunit 6B isoform 1 O. aries 100.0 417
XP_002723309.1 PREDICTED: proteasome 26S ATPase subunit 4 isoform 1 O. cuniculus 100.0 417
XP_003227715.1 PREDICTED: 26S protease regulatory subunit 6B-like isoform 1 A. carolinensis 99.8 417
XP_003977146.1 PREDICTED: 26S protease regulatory subunit 6B-like isoform 1 T. rubripes 99.8 416
XP_004078465.1 PREDICTED: 26S protease regulatory subunit 6B-like isoform 1 O. latipes 99.8 416
XP_003451328.1 PREDICTED: 26S protease regulatory subunit 6B O. niloticus 99.8 415
XP_001518401.2 PREDICTED: 26S protease regulatory subunit 6B-like O. anatinus 99.7 355
NP_956044.2 psmc4 gene product D. rerio 99.5 417
NP_001188178.1 26S protease regulatory subunit 6b I. punctatus 99.5 417
NP_001140138.1 26S protease regulatory subunit 6B S. salar 99.5 417
NP_001083300.1 proteasome 26S ATPase subunit 4 isoform 1 X. laevis 99.3 419
NP_572686.1 regulatory particle triple-A ATPase 3 D. melanogaster 95.4 411
NP_200637.1 regulatory particle triple-A ATPase 3 A. thaliana 91.0 401
NP_498429.1 Protein RPT-3 C. elegans 89.0 409
XP_959904.1 26S protease regulatory subunit 6B N. crassa 87.3 415
NP_010682.3 proteasome regulatory particle base subunit RPT3 S. cerevisiae 81.1 427
XP_001690446.1 26S proteasome regulatory subunit C. reinhardtii 64.3 373
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
NP_001121376.1 uncharacterized protein LOC100158464 X. tropicalis 99.3 417
XP_002158042.1 PREDICTED: 26S protease regulatory subunit 6B-like H. magnipapillata 96.6 384

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; ovary; brain; skin; placenta; testis; uncharacterized tissue; lung; embryonic tissue; mixed; uterus; eye; lymph; intestine; liver; bone; blood; adrenal gland; stomach; bone marrow; mammary gland; kidney; connective tissue; cervix; prostate; tonsil; spleen; salivary gland; heart; muscle; pharynx; lymph node; bladder; ear; ascites; mouth; thyroid; umbilical cord; adipose tissue; nerve; vascular; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.11-q13.13
UniSTS entry: Chr 19 RH98237
UniSTS entry: Chr 19 STS-T26522 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AF020736.1 Homo sapiens ATPase homolog mRNA, complete cds PA
BT007232.1 Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 mRNA, complete cds P
NM_006503.3 Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), transcript variant 1, mRNA P
U27515.1 Human MIP224 (MIP224) mRNA, complete cds PA
BC000343.2 Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4, mRNA (cDNA clone MGC:8570 IMAGE:2823007), complete cds PA
BC010396.1 Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4, mRNA (cDNA clone MGC:13687 IMAGE:4046205), complete cds PA
BC014488.1 Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4, mRNA (cDNA clone MGC:23214 IMAGE:4899042), complete cds PA
AK290285.1 Homo sapiens cDNA FLJ78505 complete cds, highly similar to Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), transcript variant 1, mRNA PA
AK313183.1 Homo sapiens cDNA, FLJ93682, Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4(PSMC4), transcript variant 1, mRNA P
BC018811.2 Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4, mRNA (cDNA clone IMAGE:2961362) PA
AF038965.1 Homo sapiens 26S proteasome ATPase subunit mRNA, complete cds PA
NM_153001.2 Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), transcript variant 2, mRNA P

EST sequences (10 of 948) [Show all sequences]

AA972844.1 Clone IMAGE:1578720 mixed 3' read A
AA992298.1 Clone IMAGE:1620463 testis 3' read A
AA928519.1 Clone IMAGE:1541343 mixed 3' read PA
AA922017.1 Clone IMAGE:1543606 mixed 3' read A
T26522.1 Clone LLAB292H12 brain 3' read A
T26523.1 Clone LLAB292H12 brain 5' read P
T26524.1 Clone LLAB292H12R brain P
AI056221.1 Clone IMAGE:1673114 mixed 3' read PA
AI131162.1 Clone IMAGE:1709666 heart 3' read PA
AI141856.1 Clone IMAGE:1691736 heart 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help