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UGID:161850     UniGene Hs.198998     Homo sapiens (human)   CHUK
Conserved helix-loop-helix ubiquitous kinase (CHUK)

Human protein-coding gene CHUK. Represented by 152 ESTs from 105 cDNA libraries. Corresponds to reference sequence NM_001278.3. [UniGene 161850 - Hs.198998]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001167720.1 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 2 P. troglodytes 100.0 744
NP_001269.3 CHUK gene product H. sapiens 100.0 744
XP_001107171.1 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 3 M. mulatta 99.9 744
XP_003904165.1 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit alpha P. anubis 99.7 744
NP_031726.2 Chuk gene product M. musculus 98.3 744
NP_001086127.1 inhibitor of nuclear factor kappa-B kinase subunit alpha X. laevis 81.7 742
NP_956611.1 chuk gene product D. rerio 71.4 745
Other hits (2 of 24) [Show all]SpeciesId(%)Len(aa)
XP_534990.2 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 C. lupus familiaris 98.8 744
NP_776446.1 CHUK gene product B. taurus 98.8 739

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; intestine; liver; uncharacterized tissue; lung; mammary gland; skin; salivary gland; bone marrow; spleen; testis; lymph node; kidney; placenta; heart; stomach; pancreas; uterus; cervix; blood; muscle; eye; trachea; thymus; larynx; bladder; bone; parathyroid; pharynx; nerve; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24-q25
UniSTS entry: Chr 10 RH15687 [Map Viewer]
UniSTS entry: Chr 1 L29953
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 GDB:335751
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AF080157.1 Homo sapiens IkB kinase-a (IKK-alpha) mRNA, complete cds PA
NM_001278.3 Homo sapiens conserved helix-loop-helix ubiquitous kinase (CHUK), mRNA PA
AY952888.2 Homo sapiens antigen MMSA-7 mRNA sequence PA
AB209028.1 Homo sapiens mRNA for conserved helix-loop-helix ubiquitous kinase variant protein P
BC092514.1 Homo sapiens conserved helix-loop-helix ubiquitous kinase, mRNA (cDNA clone MGC:104955 IMAGE:3063613), complete cds PA
BC034796.1 Homo sapiens conserved helix-loop-helix ubiquitous kinase, mRNA (cDNA clone IMAGE:4826379) A
U22512.1 Human helix-loop-helix protein CHUK mRNA, complete cds P
AF012890.1 Homo sapiens IKK-a kinase (IKK-a) mRNA, complete cds P
AF009225.1 Homo sapiens IkB kinase alpha subunit (IKK alpha) mRNA, complete cds P

EST sequences (10 of 152) [Show all sequences]

R22180.1 Clone IMAGE:130817 placenta 5' read
AI148163.1 Clone IMAGE:1704091 brain 3' read A
BX105039.1 Clone IMAGp998G11236_;_IMAGE:152098 placenta
CB159659.1 Clone L18POOL1n1-25-D11 liver 5' read P
CB152455.1 Clone C1SNU17-39-E05 cervix 5' read P
CB216143.1 Clone IMAGE:5937980 uterus 5' read P
AI630705.1 Clone ad14f08 blood A
AI763039.1 Clone IMAGE:2398103 kidney 3' read
AI829429.1 Clone IMAGE:2425200 uterus 3' read A
T11344.1 Clone hbc1207 pancreas 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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