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UGID:161156     UniGene Hs.194148     Homo sapiens (human)   YES1
V-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1)

Human protein-coding gene YES1. Represented by 294 ESTs from 163 cDNA libraries. Corresponds to reference sequence NM_005433.3. [UniGene 161156 - Hs.194148]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001148240.1 PREDICTED: tyrosine-protein kinase Yes isoform 9 P. troglodytes 100.0 542
NP_005424.1 YES1 gene product H. sapiens 100.0 542
XP_001087926.1 PREDICTED: proto-oncogene tyrosine-protein kinase Yes isoform 3 M. mulatta 99.8 542
XP_003914257.1 PREDICTED: tyrosine-protein kinase Yes P. anubis 99.8 542
NP_001192061.1 Yes1 gene product M. musculus 98.9 540
NP_001079938.1 tyrosine-protein kinase Yes X. laevis 95.9 536
NP_001013288.2 yes1 gene product D. rerio 94.1 545
NP_476849.1 Src oncogene at 42A, isoform A D. melanogaster 65.7 462
NP_490866.4 Protein SRC-1 C. elegans 59.6 530
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
XP_001492386.1 PREDICTED: tyrosine-protein kinase Yes E. caballus 99.5 540
NP_001094530.1 YES1 gene product B. taurus 99.3 540

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; uncharacterized tissue; brain; placenta; vascular; mixed; intestine; muscle; mouth; uterus; liver; pancreas; lung; ear; esophagus; embryonic tissue; kidney; mammary gland; bone marrow; trachea; skin; stomach; thyroid; pituitary gland; thymus; adrenal gland; ovary; bone; prostate; eye; heart; bladder; salivary gland; ascites; ganglia; adipose tissue; parathyroid
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18p11.31-p11.21
UniSTS entry: Chr 22 RH69573
UniSTS entry: Chr 3 STS-R69158 [Map Viewer]
UniSTS entry: Chr 18 RH69080
UniSTS entry: Chr 18 STS-M15990
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 22 D22S1032
UniSTS entry: Chr 1 L18426
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

BC048960.1 Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1, mRNA (cDNA clone MGC:57116 IMAGE:5260751), complete cds PA
NM_005433.3 Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1), mRNA P
AK314063.1 Homo sapiens cDNA, FLJ94729, highly similar to Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1(YES1), mRNA P
BC031080.1 Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1, mRNA (cDNA clone IMAGE:5296819), with apparent retained intron PA
M15990.1 Human c-yes-1 mRNA P

EST sequences (10 of 294) [Show all sequences]

AA885621.1 Clone IMAGE:1499943 lung 3' read A
AI122986.1 Clone IMAGE:1509866 mixed 3' read A
AI124049.1 Clone IMAGE:1694457 heart 3' read P
BX110440.1 Clone IMAGp998K03208_;_IMAGE:141434 placenta
R25397.1 Clone IMAGE:133178 placenta 3' read A
R28423.1 Clone IMAGE:133178 placenta 5' read
CB145677.1 Clone L16HLK3-9-C08 liver 5' read
R34633.1 Clone IMAGE:36795 brain 5' read
AI299096.1 Clone IMAGE:1898246 lung 3' read
AI352088.1 Clone IMAGE:1940439 embryonic tissue 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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