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UGID:159102     UniGene Hs.180346     Homo sapiens (human)   HOGA1
4-hydroxy-2-oxoglutarate aldolase 1 (HOGA1)

Human protein-coding gene HOGA1. Represented by 45 ESTs from 27 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 159102 - Hs.180346]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001164461.1 PREDICTED: probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform 2 P. troglodytes 100.0 326
NP_612422.2 HOGA1 gene product H. sapiens 100.0 326
NP_080428.1 Hoga1 gene product M. musculus 90.3 320
NP_001088351.1 probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial precursor X. laevis 75.9 295
NP_998035.1 hoga1 gene product D. rerio 71.5 297
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_003904131.1 PREDICTED: probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial P. anubis 99.1 326
NP_001177098.1 HOGA1 gene product S. scrofa 95.1 326

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; kidney; brain; prostate; bladder; liver; salivary gland; adrenal gland; pineal gland; skin; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24.2
UniSTS entry: Chr 10 RH94255
UniSTS entry: Chr 10 STS-R89840 [Map Viewer]
UniSTS entry: Chr 10 RH140725
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

BC045550.1 Homo sapiens chromosome 10 open reading frame 65, mRNA (cDNA clone MGC:57219 IMAGE:5274464), complete cds PA
BC057821.1 Homo sapiens chromosome 10 open reading frame 65, mRNA (cDNA clone MGC:71779 IMAGE:5263339), complete cds PA
BC011916.2 Homo sapiens chromosome 10 open reading frame 65, mRNA (cDNA clone MGC:20590 IMAGE:4310241), complete cds PA
AK289440.1 Homo sapiens cDNA FLJ75354 complete cds P
NM_138413.3 Homo sapiens 4-hydroxy-2-oxoglutarate aldolase 1 (HOGA1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
NM_001134670.1 Homo sapiens 4-hydroxy-2-oxoglutarate aldolase 1 (HOGA1), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA PA

EST sequences (10 of 45) [Show all sequences]

BX097583.1 Clone IMAGp998D14920_;_IMAGE:395485 pineal gland
AI241246.1 Clone IMAGE:1868171 kidney 3' read A
BX281317.1 Clone IMAGp998L1811459_;_IMAGE:5184161 mixed P
CF147355.1 Clone IMAGE:30571114 prostate 5' read
AW779690.1 Clone IMAGE:3034426 kidney 3' read A
BP197610.1 Clone ADG06406 adrenal gland 5' read
BP198092.1 Clone ADG07760 adrenal gland 5' read
BP334104.1 Clone SLV05460 salivary gland 5' read
BP275157.1 Clone KDN02957 kidney 5' read P
BP275296.1 Clone KDN03264 kidney 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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