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UGID:133742     UniGene Hs.17860     Homo sapiens (human)   OGDHL
Oxoglutarate dehydrogenase-like (OGDHL)

Human protein-coding gene OGDHL. Represented by 377 ESTs from 82 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 133742 - Hs.17860]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_060715.2 OGDHL gene product H. sapiens 100.0 1009
XP_003903666.1 PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial isoform 1 P. anubis 99.6 1009
XP_001106974.2 PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial-like isoform 1 M. mulatta 99.5 1036
NP_001074599.1 2-oxoglutarate dehydrogenase-like, mitochondrial M. musculus 97.1 1028
NP_001087546.1 2-oxoglutarate dehydrogenase-like, mitochondrial precursor X. laevis 90.9 1017
XP_001338181.2 PREDICTED: si:ch211-229p19.3 isoform 1 D. rerio 85.6 1016
NP_730223.1 neural conserved at 73EF, isoform A D. melanogaster 73.6 984
NP_500617.1 Protein OGDH-1 C. elegans 64.9 1018
NP_191101.2 2-oxoglutarate dehydrogenase, E1 component A. thaliana 58.5 954
XP_001692870.1 2-oxoglutarate dehydrogenase, E1 subunit C. reinhardtii 56.9 1008
XP_963248.2 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor N. crassa 53.7 982
NP_012141.1 alpha-ketoglutarate dehydrogenase KGD1 S. cerevisiae 53.2 962
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
XP_003318014.1 PREDICTED: oxoglutarate dehydrogenase-like P. troglodytes 99.1 952
XP_003133157.2 PREDICTED: LOW QUALITY PROTEIN: oxoglutarate dehydrogenase-like S. scrofa 98.5 1009

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; uncharacterized tissue; pancreas; eye; testis; mixed; embryonic tissue; uterus; lung; pituitary gland; salivary gland; umbilical cord; liver; ovary; thymus; trachea; thyroid; nerve; muscle; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q11.23
UniSTS entry: Chr 10 RH44536 [Map Viewer]
UniSTS entry: Chr 10 STS-T96627 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AB033116.3 Homo sapiens mRNA for KIAA1290 protein, partial cds P
AK001713.1 Homo sapiens cDNA FLJ10851 fis, clone NT2RP4001483, moderately similar to 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT PRECURSOR (EC 1.2.4.2) P
NM_018245.2 Homo sapiens oxoglutarate dehydrogenase-like (OGDHL), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
AK290226.1 Homo sapiens cDNA FLJ77902 complete cds PA
AK307759.1 Homo sapiens cDNA, FLJ97707 P
BC026320.1 Homo sapiens oxoglutarate dehydrogenase-like, mRNA (cDNA clone MGC:26169 IMAGE:4797814), complete cds PA
AK303729.1 Homo sapiens cDNA FLJ61528 complete cds, highly similar to Homo sapiens oxoglutarate dehydrogenase-like (OGDHL), mRNA PA
AK296551.1 Homo sapiens cDNA FLJ55334 complete cds, highly similar to Homo sapiens oxoglutarate dehydrogenase-like (OGDHL), mRNA P
NM_001143997.1 Homo sapiens oxoglutarate dehydrogenase-like (OGDHL), nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA PA
NM_001143996.1 Homo sapiens oxoglutarate dehydrogenase-like (OGDHL), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA PA

EST sequences (10 of 377) [Show all sequences]

AA834200.1 Clone IMAGE:1421191 kidney
AI269345.1 Clone IMAGE:1865216 kidney 3' read A
AA948651.1 Clone IMAGE:1588550 kidney 3' read A
AI289176.1 Clone IMAGE:1899309 kidney 3' read A
R59722.1 Clone IMAGE:42793 brain 3' read A
BX283119.1 Clone IMAGp958A21784_;_IMAGE:3937820 lung P
CD106750.1 Clone IMAGE:30366393 pituitary gland 5' read P
BX333646.2 Clone CS0DC028YD08 uncharacterized tissue 5' read P
BX332098.2 Clone CS0DC007YF21 uncharacterized tissue 5' read P
CD251600.1 Clone IMAGE:30384165 pituitary gland 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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